New insights into the variability of lactic acid production in Lachancea thermotolerans at the phenotypic and genomic level.
Binding Sites
Biological Variation, Population
Fungal Proteins
/ genetics
Gene Expression Regulation, Fungal
Genome, Fungal
L-Lactate Dehydrogenase
/ genetics
Lactic Acid
/ biosynthesis
Molecular Sequence Annotation
Phylogeny
Promoter Regions, Genetic
Saccharomycetales
/ genetics
Whole Genome Sequencing
Wine
/ microbiology
Biological acidification
Gene expression
Intraspecific variability
L(+)-Lactic acid
Lachancea thermotolerans
Whole-genome sequencing
Journal
Microbiological research
ISSN: 1618-0623
Titre abrégé: Microbiol Res
Pays: Germany
ID NLM: 9437794
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
15
04
2020
revised:
03
06
2020
accepted:
05
06
2020
pubmed:
28
6
2020
medline:
24
3
2021
entrez:
28
6
2020
Statut:
ppublish
Résumé
Non-conventional yeasts are increasingly applied in fermented beverage industry to obtain distinctive products with improved quality. Among these yeasts, Lachancea thermotolerans has multiple features of industrial relevance, especially the production of l(+)-lactic acid (LA), useful for the biological acidification of wine and beer. Since few information is available on this peculiar activity, the current study aimed to explore the physiological and genetic variability among L. thermotolerans strains. From a strain collection, mostly isolated from wine, a huge phenotypic diversity was acknowledged and allowed the selection of a high (SOL13) and a low (COLC27) LA producer. Comparative whole-genome sequencing of these two selected strains and the type strain CBS 6340
Identifiants
pubmed: 32593090
pii: S0944-5013(20)30393-1
doi: 10.1016/j.micres.2020.126525
pii:
doi:
Substances chimiques
Fungal Proteins
0
Lactic Acid
33X04XA5AT
L-Lactate Dehydrogenase
EC 1.1.1.27
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
126525Informations de copyright
Copyright © 2020 Elsevier GmbH. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no conflict of interest.