M Vikkula

Affiliations
  • Human Molecular Genetics, de Duve Institute, University of Louvain, Brussels, Belgium.
  • VASCERN VASCA European Reference Centre, Center for Vascular Anomalies, Division of Plastic Surgery, University Clinics Saint-Luc, University of Louvain, Brussels, Belgium.
  • Walloon Excellence in Lifesciences and Biotechnology (WELBIO), de Duve Institute, University of Louvain, Brussels, Belgium.

Publications (67)

First International Conference on RASopathies and Neurofibromatoses in Asia: Identification and advances of new therapeutics.

American journal of medical genetics. Part A
Avec: Katherine A Rauen , Abeer Alsaegh , Shay Ben-Shachar , Yemima Berman , Jaishri Blakeley , Isabel Cordeiro , Ype Elgersma , D Gareth Evans , Michael J Fisher , Ian M Frayling , Joshi George , Susan M Huson , Bronwyn Kerr , Uday Khire , Bruce Korf , Eric Legius , Ludwine Messiaen , Rick van Minkelen , Sheela Nampoothiri , Joanne Ngeow , Luis F Parada , Shubha Phadke , Ashok Pillai , Scott R Plotkin , Ratna Puri , Anup Raji , Vijaya Ramesh , Nancy Ratner , Suma P Shankar , Sheetal Sharda , Anant Tambe , Miikka Vikkula , Brigitte C Widemann , Pierre Wolkenstein , Meena Upadhyaya

Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases.

Nature communications
Avec: Adrien Georges , Min-Lee Yang , Takiy-Eddine Berrandou , Mark K Bakker , Ozan Dikilitas , Soto Romuald Kiando , Lijiang Ma , Benjamin A Satterfield , Sebanti Sengupta , Mengyao Yu , Jean-François Deleuze , Delia Dupré , Kristina L Hunker , Sergiy Kyryachenko , Lu Liu , Ines Sayoud-Sadeg , Laurence Amar , Chad M Brummett , Dawn M Coleman , Valentina d'Escamard , Peter de Leeuw , Natalia Fendrikova-Mahlay , Daniella Kadian-Dodov , Jun Z Li , Aurélien Lorthioir , Marco Pappaccogli , Aleksander Prejbisz , Witold Smigielski , James C Stanley , Matthew Zawistowski , Xiang Zhou , Sebastian Zöllner , Auteur inconnu , Auteur inconnu , Auteur inconnu , Philippe Amouyel , Marc L De Buyzere , Stéphanie Debette , Piotr Dobrowolski , Wojciech Drygas , Heather L Gornik , Jeffrey W Olin , Jerzy Piwonski , Ernst R Rietzschel , Ynte M Ruigrok , Miikka Vikkula , Ewa Warchol Celinska , Andrzej Januszewicz , Iftikhar J Kullo , Michel Azizi , Auteur inconnu , Xavier Jeunemaitre , Alexandre Persu , Jason C Kovacic , Santhi K Ganesh , Nabila Bouatia-Naji

Efficacy of Sirolimus in Patients Requiring Tracheostomy for Life-Threatening Lymphatic Malformation of the Head and Neck: A Report From the European Reference Network.

Frontiers in pediatrics
Avec: Annegret Holm , Maroeska Te Loo , Leo Schultze Kool , Päivi Salminen , Veronica Celis , Eulalia Baselga , Sophie Duignan , Veronika Dvorakova , Alan D Irvine , Laurence M Boon , Miikka Vikkula , Nader Ghaffarpour , Charlotte M Niemeyer , Jochen Rössler , Friedrich G Kapp

Dysregulation of Rho GTPases in orofacial cleft patients-derived primary cells leads to impaired cell migration, a potential cause of cleft/lip palate development.

Cells & development
Avec: Mirvat El-Sibai , Joelle El Hajj , Maria Al Haddad , Nada El Baba , Mounir Al Saneh , Wassim Daoud Khatoun , Raphaël Helaers , Miikka Vikkula , Oula El Atat , Joseph Sabbagh , Naji Abou Chebel , Michella Ghassibe-Sabbagh

A review of mechanisms of disease across PIK3CA-related disorders with vascular manifestations.

Orphanet journal of rare diseases
Avec: Guillaume Canaud , Adrienne M Hammill , Denise Adams , Miikka Vikkula , Kim M Keppler-Noreuil

GNA11-mutated Sturge-Weber syndrome has distinct neurological and dermatological features.

European journal of neurology
Avec: Anne Dompmartin , Carine J M van der Vleuten , Valérie Dekeuleneer , Thierry Duprez , Nicole Revencu , Julie Désir , D Maroeska W M Te Loo , Uta Flucke , Astrid Eijkelenboom , Leo Schultze Kool , Miikka Vikkula , Laurence Boon

Excalibur: A new ensemble method based on an optimal combination of aggregation tests for rare-variant association testing for sequencing data.

PLoS computational biology
Avec: Simon Boutry , Raphaël Helaers , Tom Lenaerts , Miikka Vikkula

The VASCERN-VASCA working group diagnostic and management pathways for lymphatic malformations.

European journal of medical genetics
Avec: Nader Ghaffarpour , Eulalia Baselga , Laurence M Boon , Andrea Diociaiuti , Anne Dompmartin , Veronika Dvorakova , May El Hachem , Paolo Gasparella , Emir Haxhija , Kristiina Kyrklund , Alan D Irvine , Friedrich G Kapp , Jochen Rößler , Päivi Salminen , Caroline van den Bosch , Carine van der Vleuten , Leo Schultze Kool , Miikka Vikkula

An endothelial SOX18-mevalonate pathway axis enables repurposing of statins for infantile hemangioma.

bioRxiv : the preprint server for biology
Avec: Annegret Holm , Matthew S Graus , Jill Wylie-Sears , Luke Borgelt , Jerry Wei Heng Tan , Sana Nasim , Long Chung , Ashish Jain , Mingwei Sun , Liang Sun , Pascal Brouillard , Ramrada Lekwuttikarn , Harry Kozakewich , Jacob Yanfei Qi , Joyce C Teng , John B Mulliken , Miikka Vikkula , Mathias Francois , Joyce Bischoff

Analysing ambiguities in trypanosomatids taxonomy by barcoding.

Memorias do Instituto Oswaldo Cruz
Avec: Carolina Boucinha , Amanda R Caetano , Helena Lc Santos , Raphael Helaers , Miikka Vikkula , Marta Helena Branquinha , André Luis Souza Dos Santos , Philippe Grellier , Karina Alessandra Morelli , Claudia Masini d'Avila-Levy

Aberrant Membrane Composition and Biophysical Properties Impair Erythrocyte Morphology and Functionality in Elliptocytosis.

Biomolecules
Avec: Hélène Pollet , Anne-Sophie Cloos , Amaury Stommen , Juliette Vanderroost , Louise Conrard , Adrien Paquot , Marine Ghodsi , Mélanie Carquin , Catherine Léonard , Manuel Guthmann , Maxime Lingurski , Christiane Vermylen , Theodore Killian , Laurent Gatto , Mark Rider , Sébastien Pyr Dit Ruys , Didier Vertommen , Miikka Vikkula , Pascal Brouillard , Patrick Van Der Smissen , Giulio G Muccioli , Donatienne Tyteca

Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations.

Structure (London, England : 1993)
Avec: Patrick Hansmann , Anne Brückner , Stephan Kiontke , Bianca Berkenfeld , Guiscard Seebohm , Pascal Brouillard , Miikka Vikkula , Floor E Jansen , Mark Nellist , Andrea Oeckinghaus , Daniel Kümmel

DNA alteration-based classification of uveal melanoma gives better prognostic stratification than immune infiltration, which has a neutral effect in high-risk group.

Cancer medicine
Avec: Deepti Narasimhaiah , Catherine Legrand , Diane Damotte , Romain Remark , Marco Munda , Patrick De Potter , Pierre G Coulie , Miikka Vikkula , Catherine Godfraind

Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation.

Nature communications
Avec: Ines Martinez-Corral , Yan Zhang , Milena Petkova , Henrik Ortsäter , Sofie Sjöberg , Sandra D Castillo , Pascal Brouillard , Louis Libbrecht , Dieter Saur , Mariona Graupera , Kari Alitalo , Laurence Boon , Miikka Vikkula , Taija Mäkinen

Increased Collagen Turnover Is a Feature of Fibromuscular Dysplasia and Associated With Hypertrophic Radial Remodeling: A Pilot, Urine Proteomic Study.

Hypertension (Dallas, Tex. : 1979)
Avec: Agnieszka Latosinska , Rosa Maria Bruno , Marco Pappaccogli , Alessandra Bacca , Christophe Beauloye , Pierre Boutouyrie , Hakim Khettab , Jan A Staessen , Stefano Taddei , Laurent Toubiana , Miikka Vikkula , Harald Mischak , Alexandre Persu

Genetic Basis and Therapies for Vascular Anomalies.

Circulation research
Avec: Angela Queisser , Emmanuel Seront , Laurence M Boon , Miikka Vikkula

Pathogenic variants in

Science translational medicine
Avec: Alicia B Byrne , Pascal Brouillard , Drew L Sutton , Jan Kazenwadel , Saba Montazaribarforoushi , Genevieve A Secker , Anna Oszmiana , Milena Babic , Kelly L Betterman , Peter J Brautigan , Melissa White , Sandra G Piltz , Paul Q Thomas , Christopher N Hahn , Matthias Rath , Ute Felbor , G Christoph Korenke , Christopher L Smith , Kathleen H Wood , Sarah E Sheppard , Denise M Adams , Ariana Kariminejad , Raphael Helaers , Laurence M Boon , Nicole Revencu , Lynette Moore , Christopher Barnett , Eric Haan , Peer Arts , Miikka Vikkula , Hamish S Scott , Natasha L Harvey

Human chromosome map of lymphedema-lymphangiogenesis genes: Template for current and future discovery.

Lymphology
Avec: M H Witte , R P Erickson , L Luy , P Brouillard , M Vikkula

Molecular pathways and possible therapies for head and neck vascular anomalies.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology
Avec: Julien Coulie , Laurence Boon , Miikka Vikkula

Clinical phenotype of adolescent and adult patients with extracranial vascular malformation.

Journal of vascular surgery. Venous and lymphatic disorders
Avec: Aleksandra Tuleja , Sarah Bernhard , Györgyi Hamvas , Themis-Areti Andreoti , Jochen Rössler , Laurence Boon , Miikka Vikkula , Rafael Kammer , Fabian Haupt , Yvonne Döring , Iris Baumgartner

Epilepsy with faint capillary malformation or reticulated telangiectasia associated with mosaic AKT3 pathogenic variants.

American journal of medical genetics. Part A
Avec: Martina De Bortoli , Marta Ivars , Nicole Revencu , Marie-Cécile Nassogne , Cinzia Lavarino , Sonia Paco , Martin Lammens , Anne Renders , Dana Dumitriu , Raphaël Helaers , Laurence M Boon , Eulalia Baselga , Miikka Vikkula

Somatic loss-of-function PIK3R1 and activating non-hotspot PIK3CA mutations associated with Capillary Malformation with Dilated Veins (CMDV).

The Journal of investigative dermatology
Avec: Martina De Bortoli , Angela Queisser , Van Cuong Pham , Anne Dompmartin , Raphaël Helaers , Simon Boutry , Cathy Claus , An-Katrien De Roo , Frank Hammer , Pascal Brouillard , Salim Abdelilah-Seyfried , Laurence M Boon , Miikka Vikkula

Targeted treatment in complex lymphatic anomaly: a case of synergistic efficacy of trametinib and sirolimus.

Orphanet journal of rare diseases
Avec: Emmanuel Seront , Antoine Froidure , Nicole Revencu , Valerie Dekeuleneer , Philippe Clapuyt , Dana Dumitriu , Miikka Vikkula , Laurence M Boon

A case report of sirolimus use in early fetal management of lymphatic malformation.

Nature cardiovascular research
Avec: Emmanuel Seront , Jean Marc Biard , An Van Damme , Nicole Revencu , Benoit Lengelé , Sandra Schmitz , Caroline de Toeuf , Philippe Clapuyt , Francis Veyckemans , Caroline Prégardien , Miikka Vikkula , Pierre Bernard , Laurence M Boon

Theranostic Advances in Vascular Malformations.

The Journal of investigative dermatology
Avec: Valérie Dekeuleneer , Emmanuel Seront , An Van Damme , Laurence M Boon , Miikka Vikkula

Journal of medical genetics
Avec: Nicole Revencu , Elodie Fastre , Marie Ravoet , Raphaël Helaers , Pascal Brouillard , Annouk Bisdorff-Bresson , Clara W T Chung , Marion Gerard , Veronika Dvorakova , Alan D Irvine , Laurence M Boon , Miikka Vikkula

Biallelic

Journal of medical genetics
Avec: Marie F Smeland , Pascal Brouillard , Trine Prescott , Laurence M Boon , Bodil Hvingel , Cecilie V Nordbakken , Mona Nystad , Øystein L Holla , Miikka Vikkula

Genetics of vascular anomalies.

Seminars in pediatric surgery
Avec: Ha-Long Nguyen , Laurence M Boon , Miikka Vikkula

Lymphatic Malformations: Genetics, Mechanisms and Therapeutic Strategies.

Circulation research
Avec: Taija Mäkinen , Laurence M Boon , Miikka Vikkula , Kari Alitalo

KRAS-driven model of Gorham-Stout disease effectively treated with trametinib.

JCI insight
Avec: Nassim Homayun-Sepehr , Anna L McCarter , Raphaël Helaers , Christine Galant , Laurence M Boon , Pascal Brouillard , Miikka Vikkula , Michael T Dellinger

Preliminary results of the European multicentric phase III trial regarding sirolimus in slow-flow vascular malformations.

JCI insight
Avec: Emmanuel Seront , An Van Damme , Catherine Legrand , Annouk Bisdorff-Bresson , Philippe Orcel , Thomas Funck-Brentano , Marie-Antoinette Sevestre , Anne Dompmartin , Isabelle Quere , Pascal Brouillard , Nicole Revencu , Martina De Bortoli , Frank Hammer , Philippe Clapuyt , Dana Dumitriu , Miikka Vikkula , Laurence M Boon

Transcriptional drifts associated with environmental changes in endothelial cells.

eLife
Avec: Yalda Afshar , Feyiang Ma , Austin Quach , Anhyo Jeong , Hannah L Sunshine , Vanessa Freitas , Yasaman Jami-Alahmadi , Raphael Helaers , Xinmin Li , Matteo Pellegrini , James A Wohlschlegel , Casey E Romanoski , Miikka Vikkula , M Luisa Iruela-Arispe

Assessment of gene-disease associations and recommendations for genetic testing for somatic variants in vascular anomalies by VASCERN-VASCA.

Orphanet journal of rare diseases
Avec: Nicole Revencu , Astrid Eijkelenboom , Claire Bracquemart , Pia Alhopuro , Judith Armstrong , Eulalia Baselga , Claudia Cesario , Maria Lisa Dentici , Melanie Eyries , Sofia Frisk , Helena Gásdal Karstensen , Nagore Gene-Olaciregui , Sirpa Kivirikko , Cinzia Lavarino , Inger-Lise Mero , Rodolphe Michiels , Elisa Pisaneschi , Bitten Schönewolf-Greulich , Ilse Wieland , Martin Zenker , Miikka Vikkula

Association of PDGFRB Mutations With Pediatric Myofibroma and Myofibromatosis.

JAMA dermatology
Avec: Guillaume Dachy , Ronald R de Krijger , Sylvie Fraitag , Ivan Théate , Bénédicte Brichard , Suma B Hoffman , Louis Libbrecht , Florence A Arts , Pascal Brouillard , Miikka Vikkula , Nisha Limaye , Jean-Baptiste Demoulin

New and Emerging Targeted Therapies for Vascular Malformations.

American journal of clinical dermatology
Avec: An Van Damme , Emmanuel Seront , Valérie Dekeuleneer , Laurence M Boon , Miikka Vikkula

Liquid biopsy for mutational profiling of locoregional recurrent and/or metastatic head and neck squamous cell carcinoma.

Oral oncology
Avec: Rachel Galot , Cédric van Marcke , Raphaël Helaers , Antonella Mendola , Rose-Marie Goebbels , Xavier Caignet , Jérôme Ambroise , Kyril Wittouck , Miikka Vikkula , Nisha Limaye , Jean-Pascal H Machiels

Non-hotspot PIK3CA mutations are more frequent in CLOVES than in common or combined lymphatic malformations.

Orphanet journal of rare diseases
Avec: Pascal Brouillard , Matthieu J Schlögel , Nassim Homayun Sepehr , Raphaël Helaers , Angela Queisser , Elodie Fastré , Simon Boutry , Sandra Schmitz , Philippe Clapuyt , Frank Hammer , Anne Dompmartin , Annamaria Weitz-Tuoretmaa , Jussi Laranne , Louise Pasquesoone , Catheline Vilain , Laurence M Boon , Miikka Vikkula

EPHB4 mutation causes adult and adolescent-onset primary lymphedema.

American journal of medical genetics. Part A
Avec: Arin K Greene , Pascal Brouillard , Christopher L Sudduth , Patrick J Smits , Dennis J Konczyk , Miikka Vikkula

Arteriovenous Cerebral High Flow Shunts in Children: From Genotype to Phenotype.

Frontiers in pediatrics
Avec: Berivan Tas , Daniele Starnoni , Stanislas Smajda , Alexandre J Vivanti , Catherine Adamsbaum , Mélanie Eyries , Judith Melki , Marcel Tawk , Augustin Ozanne , Nicole Revencu , Florent Soubrier , Selima Siala , Miikka Vikkula , Kumaran Deiva , Guillaume Saliou

The VASCERN-VASCA working group diagnostic and management pathways for severe and/or rare infantile hemangiomas.

European journal of medical genetics
Avec: Andrea Diociaiuti , Eulalia Baselga , Laurence M Boon , Anne Dompmartin , Veronika Dvorakova , May El Hachem , Paolo Gasparella , Emir Haxhija , Nader Ghaffarpour , Kristiina Kyrklund , Alan D Irvine , Friedrich G Kapp , Jochen Rößler , Päivi Salminen , Caroline van den Bosch , Carine van der Vleuten , Leo Schultze Kool , Miikka Vikkula

Trametinib as a promising therapeutic option in alleviating vascular defects in an endothelial KRAS-induced mouse model.

Human molecular genetics
Avec: Ha-Long Nguyen , Laurence M Boon , Miikka Vikkula

Ureteropelvic junction obstruction with primary lymphoedema associated with

Journal of medical genetics
Avec: Murat Alpaslan , Sandrine Mestré-Godin , Aurélie Lay , Guido Giacalone , Raphaël Helaers , Salma Adham , Hélène Kovacsik , Sophie Guillemard , Erick Mercier , Laurence Boon , Nicole Revencu , Pascal Brouillard , Isabelle Quere , Miikka Vikkula

Toward reporting standards for the pathogenicity of variant combinations involved in multilocus/oligogenic diseases.

HGG advances
Avec: Sofia Papadimitriou , Barbara Gravel , Charlotte Nachtegael , Elfride De Baere , Bart Loeys , Miikka Vikkula , Guillaume Smits , Tom Lenaerts

The VASCERN-VASCA Working Group Diagnostic and Management Pathways for Venous Malformations.

Journal of vascular anomalies
Avec: Anne Dompmartin , Eulalia Baselga , Laurence M Boon , Andrea Diociaiuti , Veronika Dvorakova , May El Hachem , Paolo Gasparella , Emir Haxhija , Nader Ghaffarpour , Kristiina Kyrklund , Alan D Irvine , Friedrich G Kapp , Jochen Rößler , Päivi Salminen , Caroline van den Bosch , Carine van der Vleuten , Leo Schultze Kool , Miikka Vikkula

Loss-of-function mutations of the TIE1 receptor tyrosine kinase cause late-onset primary lymphedema.

The Journal of clinical investigation
Avec: Pascal Brouillard , Aino Murtomäki , Veli-Matti Leppänen , Marko Hyytiäinen , Sandrine Mestre , Lucas Potier , Laurence M Boon , Nicole Revencu , Arin K Greene , Andrey Anisimov , Miia H Salo , Reetta Hinttala , Lauri Eklund , Isabelle Quéré , Kari Alitalo , Miikka Vikkula

Case report study of thalidomide therapy in 18 patients with severe arteriovenous malformations.

Nature cardiovascular research
Avec: Laurence M Boon , Valérie Dekeuleneer , Julien Coulie , Liliane Marot , Anne-Christine Bataille , Frank Hammer , Philippe Clapuyt , Anne Jeanjean , Anne Dompmartin , Miikka Vikkula

Non-Hotspot PIK3CA Variants Have Higher Variant Allele Frequency and are More Common in Syndromic Vascular Malformations.

American journal of medical genetics. Part A
Avec: Themis-Areti A Andreoti , Massimo Maiolo , Aleksandra Tuleja , Yvonne Döring , André Schaller , Erik Vassella , Laurence M Boon , Iris Baumgartner , Sarah M Bernhard , Christiane Zweier , Miikka Vikkula , Jochen Rössler

Hypotrichosis-lymphedema-telangiectasia syndrome: Report of ileal atresia associated with a SOX18 de novo pathogenic variant and review of the phenotypic spectrum.

American journal of medical genetics. Part A
Avec: Richard Coulie , Dmitriy M Niyazov , Michael J Gambello , Elodie Fastré , Pascal Brouillard , Miikka Vikkula

Lack of FAM20A, Ectopic Gingival Mineralization and Chondro/Osteogenic Modifications in Enamel Renal Syndrome.

Frontiers in cell and developmental biology
Avec: Victor Simancas Escorcia , Abdoulaziz Diarra , Adrien Naveau , Arnaud Dessombz , Rufino Felizardo , Vidjeacoumary Cannaya , Christos Chatziantoniou , Mickaël Quentric , Miikka Vikkula , Olivier Cases , Ariane Berdal , Muriel De La Dure-Molla , Renata Kozyraki

First Draft Genome of the Trypanosomatid

Tropical medicine and infectious disease
Avec: Claudia M d'Avila-Levy , Bertrand Bearzatto , Jérôme Ambroise , Raphaël Helaers , Anzhelika Butenko , Vyacheslav Yurchenko , Karina A Morelli , Helena L C Santos , Pascal Brouillard , Philippe Grellier , Jean-Luc Gala , Miikka Vikkula

Guidance for the Management of Patients with Vascular Disease or Cardiovascular Risk Factors and COVID-19: Position Paper from VAS-European Independent Foundation in Angiology/Vascular Medicine.

Thrombosis and haemostasis
Avec: Grigoris T Gerotziafas , Mariella Catalano , Mary-Paula Colgan , Zsolt Pecsvarady , Jean Claude Wautrecht , Bahare Fazeli , Dan-Mircea Olinic , Katalin Farkas , Ismail Elalamy , Anna Falanga , Jawed Fareed , Chryssa Papageorgiou , Rosella S Arellano , Petros Agathagelou , Darco Antic , Luciana Auad , Ljiljana Banfic , John R Bartolomew , Bela Benczur , Melissa B Bernardo , Francesco Boccardo , Renate Cifkova , Benilde Cosmi , Sergio De Marchi , Evangelos Dimakakos , Meletios A Dimopoulos , Gabriel Dimitrov , Isabelle Durand-Zaleski , Michael Edmonds , Essam Abo El Nazar , Dilek Erer , Omar L Esponda , Paolo Gresele , Michael Gschwandtner , Yongquan Gu , Mónica Heinzmann , Naomi M Hamburg , Amer Hamadé , Noor-Ahmed Jatoi , Oguz Karahan , Debora Karetova , Thomas Karplus , Peter Klein-Weigel , Endre Kolossvary , Matija Kozak , Eleftheria Lefkou , Gianfranco Lessiani , Aaron Liew , Antonella Marcoccia , Peter Marshang , George Marakomichelakis , Jiri Matuska , Luc Moraglia , Sergio Pillon , Pavel Poredos , Manlio Prior , David Raymund K Salvador , Oliver Schlager , Gerit Schernthaner , Alexander Sieron , Jonas Spaak , Alex Spyropoulos , Muriel Sprynger , Dusan Suput , Agata Stanek , Viera Stvrtinova , Andrzej Szuba , Alfonso Tafur , Patrick Vandreden , Panagiotis E Vardas , Dragan Vasic , Miikka Vikkula , Paul Wennberg , Zhenguo Zhai , Auteur inconnu

Likely Pathogenic Variants in One Third of Non-Syndromic Discontinuous Cleft Lip and Palate Patients.

Genes
Avec: Bénédicte Demeer , Nicole Revencu , Raphael Helaers , Cica Gbaguidi , Stéphanie Dakpe , Geneviève François , Bernard Devauchelle , Bénédicte Bayet , Miikka Vikkula

A Clinical Feasibility Study to Image Angiogenesis in Patients with Arteriovenous Malformations Using

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Avec: Daphne Lobeek , Frédérique C M Bouwman , Erik H J G Aarntzen , Janneke D M Molkenboer-Kuenen , Uta E Flucke , Ha-Long Nguyen , Miikka Vikkula , Laurence M Boon , Willemijn Klein , Peter Laverman , Wim J G Oyen , Otto C Boerman , Samantha Y A Terry , Leo J Schultze Kool , Mark Rijpkema

Rapamycin and treatment of venous malformations.

Current opinion in hematology
Avec: Emmanuel Seront , An Van Damme , Laurence M Boon , Miikka Vikkula

Mutations in Chromatin Modifier and Ephrin Signaling Genes in Vein of Galen Malformation.

Neuron
Avec: Daniel Duran , Xue Zeng , Sheng Chih Jin , Jungmin Choi , Carol Nelson-Williams , Bogdan Yatsula , Jonathan Gaillard , Charuta Gavankar Furey , Qiongshi Lu , Andrew T Timberlake , Weilai Dong , Michelle A Sorscher , Erin Loring , Jennifer Klein , August Allocco , Ava Hunt , Sierra Conine , Jason K Karimy , Mark W Youngblood , Jinwei Zhang , Michael L DiLuna , Charles C Matouk , Shrikant Mane , Irina R Tikhonova , Christopher Castaldi , Francesc López-Giráldez , James Knight , Shozeb Haider , Mariya Soban , Seth L Alper , Masaki Komiyama , Andrew F Ducruet , Joseph M Zabramski , Alan Dardik , Brian P Walcott , Christopher J Stapleton , Beverly Aagaard-Kienitz , Georges Rodesch , Eric Jackson , Edward R Smith , Darren B Orbach , Alejandro Berenstein , Kaya Bilguvar , Miikka Vikkula , Murat Gunel , Richard P Lifton , Kristopher T Kahle

Tumor sequencing is useful to refine the analysis of germline variants in unexplained high-risk breast cancer families.

Breast cancer research : BCR
Avec: Cédric Van Marcke , Raphaël Helaers , Anne De Leener , Ahmad Merhi , Céline A Schoonjans , Jérôme Ambroise , Christine Galant , Paul Delrée , Françoise Rothé , Isabelle Bar , Elsa Khoury , Pascal Brouillard , Jean-Luc Canon , Peter Vuylsteke , Jean-Pascal Machiels , Martine Berlière , Nisha Limaye , Miikka Vikkula , François P Duhoux

Characterization of

Science translational medicine
Avec: Veli-Matti Leppänen , Pascal Brouillard , Emilia A Korhonen , Tuomas Sipilä , Sawan Kumar Jha , Nicole Revencu , Veerle Labarque , Elodie Fastré , Matthieu Schlögel , Marie Ravoet , Amihood Singer , Claudia Luzzatto , Donatella Angelone , Giovanni Crichiutti , Angela D'Elia , Jaakko Kuurne , Harri Elamaa , Gou Young Koh , Pipsa Saharinen , Miikka Vikkula , Kari Alitalo

Primary lymphoedema.

Nature reviews. Disease primers
Avec: Pascal Brouillard , Marlys H Witte , Robert P Erickson , Robert J Damstra , Corinne Becker , Isabelle Quéré , Miikka Vikkula

Injectable chitosan hydrogel effectively controls lesion growth in a venous malformation murine model.

Diagnostic and interventional imaging
Avec: Ha-Long Nguyen , Ricardo Holderbaum Do Amaral , Sophie Lerouge , An-Katrien De Roo , Fatemeh Zehtabi , Miikka Vikkula , Gilles Soulez

Pathogenic variants in HGF give rise to childhood-to-late onset primary lymphoedema by loss of function.

Human molecular genetics
Avec: Murat Alpaslan , Elodie Fastré , Sandrine Mestre , Arie van Haeringen , Gabriela M Repetto , Kathelijn Keymolen , Laurence M Boon , Florence Belva , Guido Giacalone , Nicole Revencu , Yves Sznajer , Katie Riches , Vaughan Keeley , Sahar Mansour , Kristiana Gordon , Silvia Martin-Almedina , Sara Dobbins , Pia Ostergaard , Isabelle Quere , Pascal Brouillard , Miikka Vikkula

Direct oral anticoagulants and venous malformations: literature review and retrospective study of 29 patients.

Research and practice in thrombosis and haemostasis
Avec: Eugénie Lagneaux , Laurence M Boon , Nicole Revencu , Miikka Vikkula , Cedric Hermans

Targeted Treatments for Vascular Malformations: Current State of the Art.

Journal of thrombosis and haemostasis : JTH
Avec: Emmanuel Seront , Cedric Hermans , Laurence M Boon , Miikka Vikkula

Splenectomy improves erythrocyte functionality in spherocytosis based on septin abundance, but not maturation defects.

Blood advances
Avec: Anne-Sophie Cloos , Hélène Pollet , Amaury Stommen , Mauriane Maja , Maxime Lingurski , Bénédicte Brichard , Catherine Lambert , Patrick Henriet , Christophe Pierreux , Sébastien Pyr Dit Ruys , Patrick Van Der Smissen , Miikka Vikkula , Laurent Gatto , Manon Martin , Pascal Brouillard , Didier Vertommen , Donatienne Tyteca

Seven cases of hereditary haemorrhagic telangiectasia-like hepatic vascular abnormalities associated with

Journal of medical genetics
Avec: Alexandre Guilhem , Sophie Dupuis-Girod , Olivier Espitia , Sophie Rivière , Julie Seguier , Mallorie Kerjouan , Christian Lavigne , Hélène Maillard , Pascal Magro , Laurent Alric , Dan Lipsker , Antoine Parrot , Vanessa Leguy , Claire Vanlemmens , Laurent Guibaud , Miikka Vikkula , Melanie Eyries , Pierre-Jean Valette , Sophie Giraud

Rare variant association on unrelated individuals in case-control studies using aggregation tests: existing methods and current limitations.

Briefings in bioinformatics
Avec: Simon Boutry , Raphaël Helaers , Tom Lenaerts , Miikka Vikkula

Molecular investigation in individuals with orofacial clefts and microphthalmia-anophthalmia-coloboma spectrum.

European journal of human genetics : EJHG
Avec: Milena Atique Tacla , Matheus de Mello Copelli , Eleonore Pairet , Isabella Lopes Monlleó , Erlane Marques Ribeiro , Elaine Lustosa Mendes , Raphaël Helaers , Tarsis Paiva Vieira , Miikka Vikkula , Vera Lúcia Gil-da-Silva-Lopes

A New Tool to Identify Pediatric Patients with Atypical Diabetes Associated with Gene Polymorphisms.

Diabetes & metabolism journal
Avec: Sophie Welsch , Antoine Harvengta , Paola Gallo , Manon Martin , Dominique Beckers , Thierry Mouraux , Nicole Seret , Marie-Christine Lebrethon , Raphael Helear , Pascal Brouillard , Miikka Vikkula , Philippe A Lysy

Réseau de co-auteurs

Miikka Vikkula 66 collaborations
Laurence M Boon 28 collaborations
Pascal Brouillard 23 collaborations
Nicole Revencu 15 collaborations
Raphaël Helaers 13 collaborations
Anne Dompmartin 8 collaborations
Emmanuel Seront 8 collaborations
Eulalia Baselga 6 collaborations
None None 5 collaborations
Leo Schultze Kool 5 collaborations
Veronika Dvorakova 5 collaborations
Alan D Irvine 5 collaborations
Laurence Boon 5 collaborations
Philippe Clapuyt 5 collaborations
An Van Damme 5 collaborations
Päivi Salminen 4 collaborations
Nader Ghaffarpour 4 collaborations
Friedrich G Kapp 4 collaborations
Valérie Dekeuleneer 4 collaborations
Simon Boutry 4 collaborations
Raphael Helaers 4 collaborations
Kari Alitalo 4 collaborations
Frank Hammer 4 collaborations
Ha-Long Nguyen 4 collaborations
Elodie Fastré 4 collaborations
Jochen Rössler 3 collaborations
Tom Lenaerts 3 collaborations
Andrea Diociaiuti 3 collaborations
May El Hachem 3 collaborations
Paolo Gasparella 3 collaborations
Emir Haxhija 3 collaborations
Kristiina Kyrklund 3 collaborations
Jochen Rößler 3 collaborations
Caroline van den Bosch 3 collaborations
Carine van der Vleuten 3 collaborations
Angela Queisser 3 collaborations
Martina De Bortoli 3 collaborations
Dana Dumitriu 3 collaborations
Isabelle Quere 3 collaborations
Nisha Limaye 3 collaborations
Jérôme Ambroise 3 collaborations
Marco Pappaccogli 2 collaborations
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Catherine Legrand 2 collaborations
Louis Libbrecht 2 collaborations
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Julien Coulie 2 collaborations
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Marie Ravoet 2 collaborations
Annouk Bisdorff-Bresson 2 collaborations
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Arin K Greene 2 collaborations
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