questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Métalloprotéines
Protéines de liaison au fer
Protéines à fer non hème
Lipoxygénases
Arachidonate lipoxygenases
Arachidonate 5-lipoxygenase
Arachidonate 5-lipoxygenase : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Lipoxygenases
Leucotriènes
Imagerie par résonance magnétique
Inflammation
Tests génétiques
Mutations
Symptômes
5
Asthme
Réactions allergiques
Crise d'asthme
Oppression thoracique
Prévention
5
Prévention de l'asthme
Allergènes
Régime alimentaire
Inflammation
Gestion du stress
Méditation
Exercice physique
Fonction pulmonaire
Traitements
5
Inhibiteurs de la lipoxygénase
Asthme
Anti-inflammatoires
Médiateurs
Acides gras oméga-3
Antioxydants
Corticostéroïdes
Réponse immunitaire
Bronchodilatateurs
Voies respiratoires
Complications
5
Infections respiratoires
Hospitalisations
Inflammation chronique
Maladies cardiovasculaires
Asthme
Dommages pulmonaires
Qualité de vie
Activités physiques
Facteurs de risque
5
Antécédents familiaux
Pollution
Tabagisme
Complications respiratoires
Infections respiratoires
Crises d'asthme
Exposition professionnelle
Irritants
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"@type": "Question",
"name": "Comment diagnostiquer une dysfonction de l'enzyme ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins peuvent mesurer les niveaux de leucotriènes et d'autres biomarqueurs."
}
},
{
"@type": "Question",
"name": "Quels examens sont utilisés pour évaluer l'inflammation ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'échographie, l'IRM et les tests de laboratoire peuvent aider à évaluer l'inflammation."
}
},
{
"@type": "Question",
"name": "Y a-t-il des tests génétiques pour l'arachidonate 5-lipoxygenase ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques peuvent identifier des mutations affectant l'enzyme, mais ils sont rares."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent un problème avec cette enzyme ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme l'asthme, les allergies ou des maladies inflammatoires peuvent indiquer un problème."
}
},
{
"@type": "Question",
"name": "Comment évaluer l'activité de l'enzyme dans le corps ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests biochimiques mesurent l'activité de l'enzyme dans des échantillons de tissus ou de sang."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une surproduction de leucotriènes ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des crises d'asthme, des réactions allergiques et des inflammations chroniques."
}
},
{
"@type": "Question",
"name": "Comment l'inflammation se manifeste-t-elle ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'inflammation peut se manifester par des rougeurs, des douleurs, un gonflement et une chaleur locale."
}
},
{
"@type": "Question",
"name": "Y a-t-il des signes d'allergies liés à cette enzyme ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des démangeaisons, des éruptions cutanées et des difficultés respiratoires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont associés à l'asthme ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent la toux, la respiration sifflante, l'essoufflement et la pression thoracique."
}
},
{
"@type": "Question",
"name": "Comment reconnaître une crise d'asthme ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une crise d'asthme se manifeste par une respiration difficile, une toux persistante et une oppression thoracique."
}
},
{
"@type": "Question",
"name": "Comment prévenir les crises d'asthme ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les allergènes, utiliser des médicaments préventifs et suivre un plan d'action personnalisé."
}
},
{
"@type": "Question",
"name": "Y a-t-il des mesures diététiques à prendre ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en fruits, légumes et oméga-3 peut aider à réduire l'inflammation."
}
},
{
"@type": "Question",
"name": "Comment gérer le stress pour prévenir l'inflammation ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques de gestion du stress comme la méditation et le yoga peuvent réduire l'inflammation."
}
},
{
"@type": "Question",
"name": "Quels exercices sont bénéfiques pour les asthmatiques ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des exercices modérés comme la marche ou la natation peuvent améliorer la fonction pulmonaire."
}
},
{
"@type": "Question",
"name": "Comment éviter les irritants environnementaux ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Évitez la fumée, la pollution et les produits chimiques irritants pour protéger vos voies respiratoires."
}
},
{
"@type": "Question",
"name": "Quels médicaments ciblent l'arachidonate 5-lipoxygenase ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les inhibiteurs de la lipoxygénase, comme le zileuton, sont utilisés pour traiter l'asthme."
}
},
{
"@type": "Question",
"name": "Comment les anti-inflammatoires aident-ils ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils réduisent l'inflammation en inhibant la production de leucotriènes et d'autres médiateurs."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements naturels disponibles ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des acides gras oméga-3 et des antioxydants peuvent aider à moduler l'inflammation."
}
},
{
"@type": "Question",
"name": "Quels sont les effets des corticostéroïdes ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les corticostéroïdes réduisent l'inflammation et la réponse immunitaire, soulageant les symptômes."
}
},
{
"@type": "Question",
"name": "Comment les bronchodilatateurs agissent-ils ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils dilatent les voies respiratoires, facilitant la respiration et réduisant les symptômes d'asthme."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec l'asthme ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des infections respiratoires, des crises d'asthme sévères et des hospitalisations."
}
},
{
"@type": "Question",
"name": "Comment l'inflammation chronique affecte-t-elle la santé ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'inflammation chronique peut entraîner des maladies cardiovasculaires et des troubles métaboliques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de développement d'allergies ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une exposition prolongée à des allergènes peut augmenter le risque de développer des allergies."
}
},
{
"@type": "Question",
"name": "Quels sont les effets à long terme de l'asthme non contrôlé ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'asthme non contrôlé peut entraîner des dommages pulmonaires permanents et une qualité de vie réduite."
}
},
{
"@type": "Question",
"name": "Comment l'asthme peut-il affecter la vie quotidienne ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'asthme peut limiter les activités physiques, affecter le sommeil et entraîner des absences scolaires ou professionnelles."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour l'asthme ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux, l'exposition à des allergènes et la pollution sont des facteurs de risque."
}
},
{
"@type": "Question",
"name": "Comment le tabagisme influence-t-il l'asthme ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme aggrave les symptômes d'asthme et augmente le risque de complications respiratoires."
}
},
{
"@type": "Question",
"name": "Y a-t-il un lien entre l'obésité et l'asthme ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'obésité est un facteur de risque qui peut aggraver les symptômes et la gravité de l'asthme."
}
},
{
"@type": "Question",
"name": "Quels rôles jouent les infections respiratoires ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les infections respiratoires peuvent déclencher des crises d'asthme et aggraver l'inflammation."
}
},
{
"@type": "Question",
"name": "Comment l'exposition professionnelle affecte-t-elle l'asthme ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exposition à des irritants ou allergènes au travail peut augmenter le risque d'asthme professionnel."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 06/04/2025
Contenu vérifié selon les dernières recommandations médicales
7 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt/Main, Germany.
6 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt/Main, Germany.
6 publications dans cette catégorie
Affiliations :
Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University, Jena, Germany.
6 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, D-10117 Berlin, Germany.
5 publications dans cette catégorie
Affiliations :
Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University, Jena, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, D-10117 Berlin, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, 60438 Frankfurt, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Department of Integrative Bioscience and Biotechnology, Konkuk University, Seoul, 05029, Republic of Korea.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Department of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, Republic of Korea. deokkun@konkuk.ac.kr.
Department of Integrative Bioscience and Biotechnology, Konkuk University, Seoul, 05029, Republic of Korea. deokkun@konkuk.ac.kr.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan. Electronic address: toshiko@fhw.oka-pu.ac.jp.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, 100730 People's Republic of China.
Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, 100005 People's Republic of China.
Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, 100730 People's Republic of China.
Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, 100005 People's Republic of China.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Division of Clinical Pharmacology, Department of Pharmacology, and Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical School, Nashville, Tennessee 37232, United States.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Institute for Clinical Pharmacology, Goethe University, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University, Max-von-Laue-Straße 9, 60438 Frankfurt, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
2 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
2 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
Intestinal obstruction represents a severe intestinal disease associated with higher mortality rates. However, the determinants of mortality in patients with intestinal obstruction remain inadequately...
A retrospective analysis was performed on a cohort of 227 patients diagnosed with intestinal obstruction at the First Hospital of Hebei Medical University, spanning the period from September 7, 2022, ...
A cohort of 227 patients diagnosed with intestinal obstruction (median age, 59.02 years [IQR, 48.95-70.85 years]) was included in our study. Malignant bowel obstruction (MBO) and COVID-19 were identif...
The study identifies MBO, gastric cancer, COVID-19, PPC, and VTE as potential risk factors for mortality in cases of intestinal obstruction. These findings highlight the necessity for continuous monit...
Intestinal obstruction is an uncommon non-obstetric condition during pregnancy which may cause maternal and fetal mortality. Clinicians are confronted with challenges in diagnosis and treatment of int...
We reported a 39-year old, gravida 7, para 2, woman who suffered from acute intestinal obstruction at 34 weeks of gestation. Ultrasonography and abdominal computed tomography were applied for intestin...
Although uncommon during pregnancy, clinical suspicion of bowel obstruction is necessary especially in women with a history of abdominal surgery. Surgical intervention is indicated when conservative t...
Presentation of congenital diaphragmatic hernia in adulthood is rare. Further, most cases are attributable to Bochdalek and Morgagni hernias with central tendon hernias being particularly uncommon. We...
To explore clinical characteristics, pathogenesis, diagnosis and treatment of intestinal obstruction due to mesodiverticular band (MDB) in children in a single center in China....
The clinical data of 20 children with acute intestinal obstruction due to MDB between 1998 and 2020 were retrospectively analyzed....
The male-to-female ratio was 14:6 in 20 cases. Except one case of 7-month pregnant stillbirth, the cases were aged from 7 days to 14 years, at the median age of 4.31 years. The common symptoms were vo...
MDB results from the remnant of vitelline vessel, and often causes acute intestinal obstruction without special clinical symptoms. Unexplained abdominal pain and distension without surgery history sho...
Preoperatively diagnosing irreversible intestinal ischemia in patients with strangulated bowel obstruction is difficult. Therefore, this study aimed to establish a prediction model for irreversible in...
We included 83 patients who underwent emergency surgery for strangulated bowel obstruction between January 2014 and March 2022. The predictors of irreversible intestinal ischemia in strangulated bowel...
The prediction model (range, 0-4) was established using a white blood cell count of ≥ 12,000/µL and the computed tomography value of peritoneal fluid that was ≥ 20 Hounsfield units. The areas of the r...
Our model may help predict irreversible intestinal ischemia that necessitates bowel resection for strangulated bowel obstruction cases and thus enable surgeons to recognize the severity of the situati...
We aimed to analyze the computed tomography (CT) imaging signs of bowel wall ischemia in patients with acute intestinal obstruction and construct an imaging prediction model to guide clinical treatmen...
An 87-year-old woman visited her primary-care doctor because of nausea and epigastric pain. Esophagogastroduodenoscopy (EGD) revealed a giant bezoar in her stomach. She was referred to our hospital af...
BACKGROUND Jejunal diverticulosis are false diverticula of the small bowel that form from outpouching of the mucosa and submucosa. They are pulsion diverticula that are often asymptomatic and can be f...
TARP syndrome, characterized by talipes equinovarus, atrial septal defect, Robin sequence, and persistent left superior vena cava, is an X-linked recessive condition caused by deleterious variants in ...
We present a male neonate diagnosed with TARP syndrome via trio whole exome sequencing who had classic features of this syndrome, although his course was additionally complicated by feeding intoleranc...
We highlight the importance of full post-mortem examination in understanding the complete spectrum of manifestations of genetic syndromes and provide a review of the literature....
Malignant small bowel obstruction (mSBO) is a common consequence of advanced malignancies. Surgical consultation is common, however data on the outcomes following an operation are lacking. We investig...
Patients with a preoperative diagnosis of mSBO who underwent intestinal bypass between 2015 and 2021 were included. Isolated colonic obstruction was excluded as was gastric outlet obstruction. Periope...
Overall, 55 patients were identified, with a mean age of 61.2 ± 14 years. The most common primary malignancy was colorectal cancer (65.5%) and 80% of patients had a preoperative diagnosis of metastati...
Patients with mSBO face a potentially terminal condition. In this study, approximately 75% of patients who underwent intestinal bypass were able to regain the ability to eat, and 49% returned to oncol...