Titre : Prégnanes

Prégnanes : Questions médicales fréquentes

Nom anglais: Pregnanes

Descriptor UI: D011278

Tree Number: D04.210.500.745

Termes MeSH sélectionnés :

Steroids

Questions fréquentes et termes MeSH associés

Diagnostic 5

#1

Comment diagnostiquer un déséquilibre hormonal lié aux prégnanes ?

Un bilan hormonal sanguin peut révéler des niveaux anormaux de prégnanes.
Déséquilibre hormonal Progestérone
#2

Quels tests sont utilisés pour mesurer les prégnanes ?

Les tests sanguins et urinaires mesurent les niveaux de progestérone et de dérivés.
Tests sanguins Progestérone
#3

Quels symptômes indiquent un problème avec les prégnanes ?

Des irrégularités menstruelles, des changements d'humeur ou des problèmes de fertilité.
Irrégularités menstruelles Fertilité
#4

Les échographies peuvent-elles aider au diagnostic ?

Oui, elles peuvent détecter des anomalies ovariennes ou utérines liées aux hormones.
Échographie Anomalies ovariennes
#5

Quand consulter un médecin pour des problèmes hormonaux ?

Si vous avez des symptômes persistants ou des changements significatifs dans votre cycle.
Consultation médicale Cycle menstruel

Symptômes 5

#1

Quels sont les symptômes d'un excès de prégnanes ?

Des symptômes peuvent inclure des saignements irréguliers et des douleurs abdominales.
Saignements irréguliers Douleurs abdominales
#2

Comment un déficit de prégnanes se manifeste-t-il ?

Il peut entraîner des troubles menstruels, de l'infertilité et des bouffées de chaleur.
Troubles menstruels Infertilité
#3

Les changements d'humeur sont-ils liés aux prégnanes ?

Oui, les fluctuations hormonales peuvent affecter l'humeur et provoquer de l'anxiété.
Changements d'humeur Anxiété
#4

Quels signes indiquent une carence en progestérone ?

Des cycles irréguliers, des douleurs mammaires et des symptômes prémenstruels intenses.
Carence en progestérone Symptômes prémenstruels
#5

Les prégnanes affectent-elles la libido ?

Oui, des niveaux anormaux peuvent entraîner une diminution de la libido chez certaines femmes.
Libido Hormones sexuelles

Prévention 5

#1

Comment prévenir les déséquilibres hormonaux ?

Maintenir un mode de vie sain, gérer le stress et consulter régulièrement un médecin.
Prévention Mode de vie sain
#2

L'alimentation influence-t-elle les niveaux de prégnanes ?

Oui, une alimentation riche en nutriments peut soutenir l'équilibre hormonal.
Alimentation Équilibre hormonal
#3

Le stress affecte-t-il les prégnanes ?

Oui, le stress chronique peut perturber la production hormonale et les niveaux de prégnanes.
Stress Production hormonale
#4

Les exercices physiques réguliers sont-ils bénéfiques ?

Oui, l'exercice aide à réguler les hormones et à maintenir un poids santé.
Exercice physique Régulation hormonale
#5

Faut-il éviter certains aliments pour la santé hormonale ?

Réduire les sucres raffinés et les graisses saturées peut aider à équilibrer les hormones.
Alimentation Santé hormonale

Traitements 5

#1

Quels traitements existent pour réguler les prégnanes ?

Des traitements hormonaux, comme la progestérone, peuvent aider à équilibrer les niveaux.
Traitements hormonaux Progestérone
#2

Les contraceptifs hormonaux influencent-ils les prégnanes ?

Oui, ils peuvent stabiliser les niveaux de prégnanes et réguler le cycle menstruel.
Contraceptifs hormonaux Cycle menstruel
#3

Comment les changements de mode de vie aident-ils ?

Une alimentation équilibrée et l'exercice régulier peuvent améliorer l'équilibre hormonal.
Mode de vie Équilibre hormonal
#4

Les suppléments de progestérone sont-ils efficaces ?

Oui, ils peuvent être prescrits pour traiter les carences en progestérone.
Suppléments de progestérone Carences hormonales
#5

Quand envisager une thérapie hormonale ?

Si les symptômes sont sévères ou persistent malgré d'autres traitements.
Thérapie hormonale Symptômes sévères

Complications 5

#1

Quelles complications peuvent survenir avec des niveaux anormaux de prégnanes ?

Des complications incluent l'infertilité, des troubles menstruels et des maladies hormonales.
Infertilité Troubles menstruels
#2

Les déséquilibres hormonaux peuvent-ils causer des maladies ?

Oui, ils peuvent augmenter le risque de maladies comme le cancer du sein ou de l'utérus.
Maladies hormonales Cancer du sein
#3

Comment les prégnanes affectent-elles la grossesse ?

Des niveaux anormaux peuvent entraîner des complications comme des fausses couches.
Grossesse Fausses couches
#4

Les prégnanes influencent-elles la santé osseuse ?

Oui, des déséquilibres peuvent affecter la densité osseuse et augmenter le risque d'ostéoporose.
Santé osseuse Ostéoporose
#5

Quels sont les risques d'un traitement hormonal inapproprié ?

Un traitement inapproprié peut aggraver les déséquilibres et causer des effets secondaires.
Traitement hormonal Effets secondaires

Facteurs de risque 5

#1

Quels facteurs augmentent le risque de déséquilibre hormonal ?

L'obésité, le stress, et des antécédents familiaux de troubles hormonaux sont des facteurs de risque.
Obésité Antécédents familiaux
#2

L'âge influence-t-il les niveaux de prégnanes ?

Oui, les niveaux hormonaux fluctuent avec l'âge, surtout pendant la périménopause.
Âge Périménopause
#3

Les maladies chroniques affectent-elles les prégnanes ?

Oui, des maladies comme le diabète peuvent perturber l'équilibre hormonal.
Maladies chroniques Diabète
#4

Le mode de vie sédentaire est-il un facteur de risque ?

Oui, un mode de vie sédentaire peut contribuer à des déséquilibres hormonaux.
Mode de vie sédentaire Déséquilibres hormonaux
#5

Les traitements médicaux peuvent-ils influencer les prégnanes ?

Oui, certains médicaments peuvent affecter la production ou l'équilibre des prégnanes.
Médicaments Production hormonale
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"https://questionsmedicales.fr/mesh/D011278?mesh_terms=Steroids#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Prégnanes", "description": "Quels sont les symptômes d'un excès de prégnanes ?\nComment un déficit de prégnanes se manifeste-t-il ?\nLes changements d'humeur sont-ils liés aux prégnanes ?\nQuels signes indiquent une carence en progestérone ?\nLes prégnanes affectent-elles la libido ?", "url": "https://questionsmedicales.fr/mesh/D011278?mesh_terms=Steroids#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Prégnanes", "description": "Comment prévenir les déséquilibres hormonaux ?\nL'alimentation influence-t-elle les niveaux de prégnanes ?\nLe stress affecte-t-il les prégnanes ?\nLes exercices physiques réguliers sont-ils bénéfiques ?\nFaut-il éviter certains aliments pour la santé hormonale ?", "url": "https://questionsmedicales.fr/mesh/D011278?mesh_terms=Steroids#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Prégnanes", "description": "Quels traitements existent pour réguler les prégnanes ?\nLes contraceptifs hormonaux influencent-ils les prégnanes ?\nComment les changements de mode de vie aident-ils ?\nLes suppléments de progestérone sont-ils efficaces ?\nQuand envisager une thérapie hormonale ?", "url": "https://questionsmedicales.fr/mesh/D011278?mesh_terms=Steroids#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Prégnanes", "description": "Quelles complications peuvent survenir avec des niveaux anormaux de prégnanes ?\nLes déséquilibres hormonaux peuvent-ils causer des maladies ?\nComment les prégnanes affectent-elles la grossesse ?\nLes prégnanes influencent-elles la santé osseuse ?\nQuels sont les risques d'un traitement hormonal inapproprié ?", "url": "https://questionsmedicales.fr/mesh/D011278?mesh_terms=Steroids#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Prégnanes", "description": "Quels facteurs augmentent le risque de déséquilibre hormonal ?\nL'âge influence-t-il les niveaux de prégnanes ?\nLes maladies chroniques affectent-elles les prégnanes ?\nLe mode de vie sédentaire est-il un facteur de risque ?\nLes traitements médicaux peuvent-ils influencer les prégnanes ?", "url": "https://questionsmedicales.fr/mesh/D011278?mesh_terms=Steroids#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer un déséquilibre hormonal lié aux prégnanes ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Un bilan hormonal sanguin peut révéler des niveaux anormaux de prégnanes." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour mesurer les prégnanes ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests sanguins et urinaires mesurent les niveaux de progestérone et de dérivés." } }, { "@type": "Question", "name": "Quels symptômes indiquent un problème avec les prégnanes ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Des irrégularités menstruelles, des changements d'humeur ou des problèmes de fertilité." } }, { "@type": "Question", "name": "Les échographies peuvent-elles aider au diagnostic ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Oui, elles peuvent détecter des anomalies ovariennes ou utérines liées aux hormones." } }, { "@type": "Question", "name": "Quand consulter un médecin pour des problèmes hormonaux ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Si vous avez des symptômes persistants ou des changements significatifs dans votre cycle." } }, { "@type": "Question", "name": "Quels sont les symptômes d'un excès de prégnanes ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes peuvent inclure des saignements irréguliers et des douleurs abdominales." } }, { "@type": "Question", "name": "Comment un déficit de prégnanes se manifeste-t-il ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Il peut entraîner des troubles menstruels, de l'infertilité et des bouffées de chaleur." } }, { "@type": "Question", "name": "Les changements d'humeur sont-ils liés aux prégnanes ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les fluctuations hormonales peuvent affecter l'humeur et provoquer de l'anxiété." } }, { "@type": "Question", "name": "Quels signes indiquent une carence en progestérone ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Des cycles irréguliers, des douleurs mammaires et des symptômes prémenstruels intenses." } }, { "@type": "Question", "name": "Les prégnanes affectent-elles la libido ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des niveaux anormaux peuvent entraîner une diminution de la libido chez certaines femmes." } }, { "@type": "Question", "name": "Comment prévenir les déséquilibres hormonaux ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Maintenir un mode de vie sain, gérer le stress et consulter régulièrement un médecin." } }, { "@type": "Question", "name": "L'alimentation influence-t-elle les niveaux de prégnanes ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Oui, une alimentation riche en nutriments peut soutenir l'équilibre hormonal." } }, { "@type": "Question", "name": "Le stress affecte-t-il les prégnanes ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Oui, le stress chronique peut perturber la production hormonale et les niveaux de prégnanes." } }, { "@type": "Question", "name": "Les exercices physiques réguliers sont-ils bénéfiques ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Oui, l'exercice aide à réguler les hormones et à maintenir un poids santé." } }, { "@type": "Question", "name": "Faut-il éviter certains aliments pour la santé hormonale ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Réduire les sucres raffinés et les graisses saturées peut aider à équilibrer les hormones." } }, { "@type": "Question", "name": "Quels traitements existent pour réguler les prégnanes ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Des traitements hormonaux, comme la progestérone, peuvent aider à équilibrer les niveaux." } }, { "@type": "Question", "name": "Les contraceptifs hormonaux influencent-ils les prégnanes ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent stabiliser les niveaux de prégnanes et réguler le cycle menstruel." } }, { "@type": "Question", "name": "Comment les changements de mode de vie aident-ils ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Une alimentation équilibrée et l'exercice régulier peuvent améliorer l'équilibre hormonal." } }, { "@type": "Question", "name": "Les suppléments de progestérone sont-ils efficaces ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent être prescrits pour traiter les carences en progestérone." } }, { "@type": "Question", "name": "Quand envisager une thérapie hormonale ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Si les symptômes sont sévères ou persistent malgré d'autres traitements." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec des niveaux anormaux de prégnanes ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications incluent l'infertilité, des troubles menstruels et des maladies hormonales." } }, { "@type": "Question", "name": "Les déséquilibres hormonaux peuvent-ils causer des maladies ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Oui, ils peuvent augmenter le risque de maladies comme le cancer du sein ou de l'utérus." } }, { "@type": "Question", "name": "Comment les prégnanes affectent-elles la grossesse ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Des niveaux anormaux peuvent entraîner des complications comme des fausses couches." } }, { "@type": "Question", "name": "Les prégnanes influencent-elles la santé osseuse ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des déséquilibres peuvent affecter la densité osseuse et augmenter le risque d'ostéoporose." } }, { "@type": "Question", "name": "Quels sont les risques d'un traitement hormonal inapproprié ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Un traitement inapproprié peut aggraver les déséquilibres et causer des effets secondaires." } }, { "@type": "Question", "name": "Quels facteurs augmentent le risque de déséquilibre hormonal ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "L'obésité, le stress, et des antécédents familiaux de troubles hormonaux sont des facteurs de risque." } }, { "@type": "Question", "name": "L'âge influence-t-il les niveaux de prégnanes ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les niveaux hormonaux fluctuent avec l'âge, surtout pendant la périménopause." } }, { "@type": "Question", "name": "Les maladies chroniques affectent-elles les prégnanes ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des maladies comme le diabète peuvent perturber l'équilibre hormonal." } }, { "@type": "Question", "name": "Le mode de vie sédentaire est-il un facteur de risque ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Oui, un mode de vie sédentaire peut contribuer à des déséquilibres hormonaux." } }, { "@type": "Question", "name": "Les traitements médicaux peuvent-ils influencer les prégnanes ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Oui, certains médicaments peuvent affecter la production ou l'équilibre des prégnanes." } } ] } ] }
Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale

Validation scientifique effectuée le 23/12/2025

Contenu vérifié selon les dernières recommandations médicales

En savoir plus sur Dr Menir

Sous-catégories

38 au total
└─

Prégnadiènes

Pregnadienes D011245 - D04.210.500.745.432
└─

Prégnanediones

Pregnanediones D011277 - D04.210.500.745.558
└─

Prégnanolone

Pregnanolone D011280 - D04.210.500.745.640
└─

Prégnatriènes

Pregnatrienes D011281 - D04.210.500.745.683
└─

Prégnènes

Pregnenes D011283 - D04.210.500.745.745
└─└─

Acide canrénoïque

Canrenoic Acid D002191 - D04.210.500.745.432.100
└─└─

Canrénone

Canrenone D002192 - D04.210.500.745.432.120
└─└─

Danazol

Danazol D003613 - D04.210.500.745.432.235
└─└─

Dydrogestérone

Dydrogesterone D004394 - D04.210.500.745.432.296
└─└─

Médrogestone

Medrogestone D008524 - D04.210.500.745.432.481
└─└─

Mégestrol

Megestrol D008535 - D04.210.500.745.432.531
└─└─

Mélengestrol

Melengestrol Acetate D008552 - D04.210.500.745.432.581
└─└─

Prégnadiènediols

Pregnadienediols D011244 - D04.210.500.745.432.719
└─└─

Prégnadiènetriols

Pregnadienetriols D011246 - D04.210.500.745.432.769
└─└─

Mélange alfaxalone alfadolone

Alfaxalone Alfadolone Mixture D000530 - D04.210.500.745.558.050
└─└─

Diméthistérone

Dimethisterone D004116 - D04.210.500.745.745.279
└─└─

Éplérénone

Eplerenone D000077545 - D04.210.500.745.745.329
└─└─

Éthistérone

Ethisterone D005003 - D04.210.500.745.745.379
└─└─

Prégnènediones

Pregnenediones D011282 - D04.210.500.745.745.654
└─└─

Spironolactone

Spironolactone D013148 - D04.210.500.745.745.855
└─└─└─

Acétate mégestrol

Megestrol Acetate D019290 - D04.210.500.745.432.531.500
└─└─└─

Furoate de mométasone

Mometasone Furoate D000068656 - D04.210.500.745.432.719.526
└─└─└─

Prednisone

Prednisone D011241 - D04.210.500.745.432.719.702
└─└─└─

Désonide

Desonide D003898 - D04.210.500.745.432.769.325
└─└─└─

Prednisolone

Prednisolone D011239 - D04.210.500.745.432.769.795
└─└─└─

Budésonide

Budesonide D019819 - D04.210.500.745.745.654.105
└─└─└─

Gestonorone caproate

Gestonorone Caproate D005866 - D04.210.500.745.745.654.527
└─└─└─

Halcinonide

Halcinonide D006206 - D04.210.500.745.745.654.570
└─└─└─

Prégnénolone carbonitrile

Pregnenolone Carbonitrile D011285 - D04.210.500.745.745.725.703
└─└─└─└─

Méthylprednisolone

Methylprednisolone D008775 - D04.210.500.745.432.769.795.539
└─└─└─└─

Prednimustine

Prednimustine D011238 - D04.210.500.745.432.769.795.700
└─└─└─└─

Fludrocortisone

Fludrocortisone D005438 - D04.210.500.745.745.654.600.500
└─└─└─└─

Algestone

Algestone D000523 - D04.210.500.745.745.654.829.025
└─└─└─└─└─

Acétate de méthylprednisolone

Methylprednisolone Acetate D000077555 - D04.210.500.745.432.769.795.539.250
└─└─└─└─└─

Méthylprednisolone succinate

Methylprednisolone Hemisuccinate D008776 - D04.210.500.745.432.769.795.539.500
└─└─└─└─└─

Algestone acétophénide

Algestone Acetophenide D000463 - D04.210.500.745.745.654.829.025.025
└─└─└─└─└─

Médroxyprogestérone

Medroxyprogesterone D008525 - D04.210.500.745.745.654.829.395.700
└─└─└─└─└─└─

Acétate de médroxyprogestérone

Medroxyprogesterone Acetate D017258 - D04.210.500.745.745.654.829.395.700.500

Auteurs principaux

Jukka Hakkola

6 publications dans cette catégorie

Affiliations :
  • Research Unit of Biomedicine and Internal Medicine, Biocenter Oulu, Medical Research Center Oulu, University of Oulu and Oulu University Hospital, Oulu, Finland.
Publications dans "Prégnanes" : Voir toutes les publications (6)

Jaana Rysä

5 publications dans cette catégorie

Affiliations :
  • School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, 70211, Kuopio, Finland. jaana.rysa@uef.fi.
Publications dans "Prégnanes" :

Essam Abdel-Sattar

4 publications dans cette catégorie

Affiliations :
  • Pharmacognosy Department, Faculty of Pharmacy, Cairo University, Giza, Egypt.
Publications dans "Prégnanes" :

Jeff L Staudinger

4 publications dans cette catégorie

Affiliations :
  • Division of Basic Sciences, Farber-McIntire Campus, College of Osteopathic Medicine, Kansas City University, Joplin, MO 64804, USA.
Publications dans "Prégnanes" :

Taosheng Chen

4 publications dans cette catégorie

Affiliations :
  • Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee taosheng.chen@stjude.org.
Publications dans "Prégnanes" :

Outi Kummu

4 publications dans cette catégorie

Affiliations :
  • Research Unit of Biomedicine, Pharmacology and Toxicology, University of Oulu, Oulu, Finland.
  • Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
Publications dans "Prégnanes" :

Do Thi Trang

3 publications dans cette catégorie

Affiliations :
  • Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
Publications dans "Prégnanes" :

Bui Huu Tai

3 publications dans cette catégorie

Affiliations :
  • Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
  • Graduate University of Science and Technology, VAST, Hanoi, Vietnam.
Publications dans "Prégnanes" :

Nguyen Xuan Nhiem

3 publications dans cette catégorie

Affiliations :
  • Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
  • Graduate University of Science and Technology, VAST, Hanoi, Vietnam.
Publications dans "Prégnanes" :

Chau Van Minh

3 publications dans cette catégorie

Affiliations :
  • Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
Publications dans "Prégnanes" :

Phan Van Kiem

3 publications dans cette catégorie

Affiliations :
  • Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
  • Graduate University of Science and Technology, VAST, Hanoi, Vietnam.
Publications dans "Prégnanes" :

Gang Chen

3 publications dans cette catégorie

Affiliations :
  • School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China. Electronic address: chengang1152001@163.com.
Publications dans "Prégnanes" :

Jie Zhang

3 publications dans cette catégorie

Affiliations :
  • College of Food Science and Engineering, Jilin University, Changchun, China.
Publications dans "Prégnanes" :

Wenwei Lin

3 publications dans cette catégorie

Affiliations :
  • Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee.
Publications dans "Prégnanes" :

Yongtao Li

3 publications dans cette catégorie

Affiliations :
  • Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee.
Publications dans "Prégnanes" :

Sergio C Chai

3 publications dans cette catégorie

Affiliations :
  • Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee.
Publications dans "Prégnanes" :

Hong Zhang

3 publications dans cette catégorie

Affiliations :
  • First People's Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology , Kunming , People's Republic of China.
Publications dans "Prégnanes" :

Mikko Karpale

3 publications dans cette catégorie

Affiliations :
  • Research Unit of Biomedicine, Pharmacology and Toxicology, University of Oulu, Oulu, Finland.
  • Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.
Publications dans "Prégnanes" :

Heidi Hautajärvi

3 publications dans cette catégorie

Affiliations :
  • Admescope Ltd., Oulu, Finland.
Publications dans "Prégnanes" :

Janne Hukkanen

3 publications dans cette catégorie

Affiliations :
  • Medical Research Center, Oulu University Hospital and University of Oulu, Oulu, Finland.
  • Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Research Unit of Internal Medicine, University of Oulu, Oulu, Finland.
Publications dans "Prégnanes" :

Sources (2258 au total)

Comparison of the Particulate Steroids, Betamethasone and Methylprednisolone, in Caudal Steroid Injection Under Ultrasound Guidance.

Oct 2023
DOI: 10.1016/j.wneu.2023.07.083 PMID: 37495099

Pain relief in lumbar disc hernias is a challenging condition. This study retrospectively compared particulate steroids, methylprednisolone acetate (mid-term effective), against betamethasone acetate ... A total of 40 patients with L4-5 and/or L5-S1 disc herniation were treated with ultrasound-guided caudal epidural injection between September 2021 and June 2022. Nineteen patients who were given methy... There was no statistically significant difference between the groups regarding age, gender, and body mass index (P > 0.05). In group A, preop VAS was 8.84 ± 0.76, immediate postop period 3.10 ± 1.37, ... No significant difference was observed between betamethasone and methylprednisolone. Both steroid groups showed a substantial improvement in the preoperative pain scores of the patients....

Humans Methylprednisolone Intervertebral Disc Displacement Methylprednisolone Acetate Retrospective Studies +6 autres

Outcomes of Frontal Sinus Stenting With Steroid Impregnated Microsponge Versus Steroid-Eluting Implant.

Nov 2023
DOI: 10.1177/19458924231186901 PMID: 37408359

Mometasone-eluting poly-L-lactide-coglycolide (MPLG) is available commercially for frontal sinus ostium (FSO) stenting. An alternative chitosan polymer-based drug delivery microsponge is also availabl... To compare the outcomes of MPLG stents versus triamcinolone-impregnated chitosan polymer (TICP) microsponge in frontal sinus surgery.... Patients who underwent endoscopic sinus surgery from December 2018 to February 2022 were reviewed to identify those with the intraoperative placement of TICP microsponge or MPLG stent in the FSO. FSO ... A total of 68 subjects and 96 FSOs were treated. TICP was first used in August 2021 and MPLG in December 2018. MPLG placement in a Draf 3 cavity was excluded since TICP had not been used during Draf 3... FSO patency for both stents was similar, although TICP had significantly lower costs per unit. Additional comparative trials may be helpful for guiding clinicians on the appropriate clinical situation...

Humans Frontal Sinus Chitosan Sinusitis Treatment Outcome +6 autres

The effect of etanercept therapy on adrenal steroid metabolism in juvenile idiopathic arthritis: a steroid metabolomics approach.

12 Apr 2023
DOI: 10.1186/s12969-023-00813-y PMID: 37046333

To evaluate the impact of anti-tumor necrosis factor-alpha (TNFα: etanercept [Etanercept ®]) therapy on adrenal activity in juvenile idiopathic arthritis (JIA) .... Eleven JIA patients aged 12 ± 6.2 years with a disease duration of 6.3 ± 5.2 years were enrolled. They were treated once weekly with etanercept (0.8 mg/kg) for 3 ± 2.8 years. Urine samples for gas chr... The levels of 21 of the 31 metabolites were low before etanercept treatment. Those 21 metabolites included 4 C19 steroids (androgens), 5 C C21 steroid hormone intermediates, 10 cortisol metabolites, a... Almost all of the pre-etanercept treatment cortisol urinary metabolite levels were significantly lower than normal, and almost all rose to normal values by 1 day after treatment. The therapeutic effec...

Humans Hydrocortisone Etanercept Arthritis, Juvenile Steroids +1 autres

Infliximab in steroid-refractory immune-related hepatitis does not demonstrate hepatotoxicity and may shorten time on steroids.

05 Jul 2024
DOI: 10.1136/jitc-2023-008074 PMID: 38969522

Immune-related hepatitis (irHepatitis) is a relatively common immune-related adverse event (irAE) of checkpoint inhibitors. Often, it responds well to steroids; however, in refractory cases, further t... We retrospectively reviewed patients treated with infliximab for steroid-refractory grade ≥3 irHepatitis at the Department of Dermatology, University Hospital Zurich. The positive response to inflixim... 10 patients with steroid-resistant irHepatitis grade ≥3 were treated with infliximab 5 mg/kg, of whom 7 (70%) responded positively. In two cases, the liver values increased over 50% before the irHepat... Treatment of irHepatitis with infliximab did not result in hepatotoxicity and led to long-lasting positive response in 9 of 10 of the cases. Further research is needed to evaluate the role of anti-TNF...

Humans Infliximab Male Female Retrospective Studies +6 autres