Jaques Fellay

Affiliations

School of Life Sciences, EPFL, 1015, Lausanne, Switzerland.
Precision Medicine Unit, Lausanne University Hospital, 1011, Lausanne, Switzerland.

ORCID: http://orcid.org/0000-0002-8240-939X

Publications (91)

Whole-exome Sequencing for the Identification of Rare Variants in Primary Immunodeficiency Genes in Children With Sepsis: A Prospective, Population-based Cohort Study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Alessandro Borghesi , Johannes Trück , Samira Asgari , Vanessa Sancho-Shimizu , Philipp K A Agyeman , Evangelos Bellos , Eric Giannoni , Martin Stocker , Klara M Posfay-Barbe , Ulrich Heininger , Sara Bernhard-Stirnemann , Anita Niederer-Loher , Christian R Kahlert , Giancarlo Natalucci , Christa Relly , Thomas Riedel , Claudia E Kuehni , Christian W Thorball , Nimisha Chaturvedi , Federico Martinon-Torres , Taco W Kuijpers , Lachlan Coin , Victoria Wright , Jethro Herberg , Michael Levin , Christoph Aebi , Christoph Berger , Jacques Fellay , Luregn J Schlapbach

Blacklisting variants common in private cohorts but not in public databases optimizes human exome analysis.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Patrick Maffucci , Benedetta Bigio , Franck Rapaport , Aurélie Cobat , Alessandro Borghesi , Marie Lopez , Etienne Patin , Alexandre Bolze , Lei Shang , Matthieu Bendavid , Eric M Scott , Peter D Stenson , Charlotte Cunningham-Rundles , David N Cooper , Joseph G Gleeson , Jacques Fellay , Lluis Quintana-Murci , Jean-Laurent Casanova , Laurent Abel , Bertrand Boisson , Yuval Itan

[Pharmacogenomics : a toolbox to improve drug prescription].

Revue medicale suisse

Avec: Evrim Jaccard , Claire Redin , François Girardin , Gérard Waeber , Jacques Fellay , Peter Vollenweider

A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response.

Nature genetics

Avec: Yang Luo , Masahiro Kanai , Wanson Choi , Xinyi Li , Saori Sakaue , Kenichi Yamamoto , Kotaro Ogawa , Maria Gutierrez-Arcelus , Peter K Gregersen , Philip E Stuart , James T Elder , Lukas Forer , Sebastian Schönherr , Christian Fuchsberger , Albert V Smith , Jacques Fellay , Mary Carrington , David W Haas , Xiuqing Guo , Nicholette D Palmer , Yii-Der Ida Chen , Jerome I Rotter , Kent D Taylor , Stephen S Rich , Adolfo Correa , James G Wilson , Sekar Kathiresan , Michael H Cho , Andres Metspalu , Tonu Esko , Yukinori Okada , Buhm Han , Auteur inconnu , Paul J McLaren , Soumya Raychaudhuri

CD38 Expression by Antigen-Specific CD4 T Cells Is Significantly Restored 5 Months After Treatment Initiation Independently of Sputum Bacterial Load at the Time of Tuberculosis Diagnosis.

Frontiers in medicine

Avec: Hellen Hiza , Jerry Hella , Ainhoa Arbués , Mohamed Sasamalo , Veronica Misana , Jacques Fellay , Sébastien Gagneux , Klaus Reither , Damien Portevin

G2GSnake: a Snakemake workflow for host-pathogen genomic association studies.

Bioinformatics advances

Avec: Zhi Ming Xu , Olivier Naret , Mariam Ait Oumelloul , Jacques Fellay

Inborn errors of type I interferon immunity in patients with symptomatic acute hepatitis E.

Hepatology (Baltimore, Md.)

Avec: Ali Saadat , Jérôme Gouttenoire , Paolo Ripellino , David Semela , Soraya Amar , Beat M Frey , Stefano Fontana , Elise Mdawar-Bailly , Darius Moradpour , Jacques Fellay , Montserrat Fraga , Auteur inconnu

The combined impact of persistent infections and human genetic variation on C-reactive protein levels.

BMC medicine

Avec: Flavia Hodel , Olivier Naret , Clara Bonnet , Nicole Brenner , Noemi Bender , Tim Waterboer , Pedro Marques-Vidal , Peter Vollenweider , Jacques Fellay

Associations of genetic and infectious risk factors with coronary heart disease.

eLife

Avec: Flavia Hodel , Zhi Ming Xu , Christian Wandall Thorball , Roxane de La Harpe , Prunelle Letang-Mathieu , Nicole Brenner , Julia Butt , Noemi Bender , Tim Waterboer , Pedro Manuel Marques-Vidal , Peter Vollenweider , Julien Vaucher , Jacques Fellay

Leukocyte Count and Coronary Artery Disease Events in People With Human Immunodeficiency Virus: A Longitudinal Study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Emma F Avery , Julia N Kleynhans , Bruno Ledergerber , Isabella C Schoepf , Christian W Thorball , Neeltje A Kootstra , Peter Reiss , Lene Ryom , Dominique L Braun , Maria C Thurnheer , Catia Marzolini , Marco Seneghini , Enos Bernasconi , Matthias Cavassini , Hélène Buvelot , Roger D Kouyos , Jacques Fellay , Huldrych F Günthard , Philip E Tarr , Auteur inconnu

Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19.

Genome medicine

Avec: Daniela Matuozzo , Estelle Talouarn , Astrid Marchal , Peng Zhang , Jeremy Manry , Yoann Seeleuthner , Yu Zhang , Alexandre Bolze , Matthieu Chaldebas , Baptiste Milisavljevic , Adrian Gervais , Paul Bastard , Takaki Asano , Lucy Bizien , Federica Barzaghi , Hassan Abolhassani , Ahmad Abou Tayoun , Alessandro Aiuti , Ilad Alavi Darazam , Luis M Allende , Rebeca Alonso-Arias , Andrés Augusto Arias , Gokhan Aytekin , Peter Bergman , Simone Bondesan , Yenan T Bryceson , Ingrid G Bustos , Oscar Cabrera-Marante , Sheila Carcel , Paola Carrera , Giorgio Casari , Khalil Chaïbi , Roger Colobran , Antonio Condino-Neto , Laura E Covill , Ottavia M Delmonte , Loubna El Zein , Carlos Flores , Peter K Gregersen , Marta Gut , Filomeen Haerynck , Rabih Halwani , Selda Hancerli , Lennart Hammarström , Nevin Hatipoğlu , Adem Karbuz , Sevgi Keles , Christèle Kyheng , Rafael Leon-Lopez , Jose Luis Franco , Davood Mansouri , Javier Martinez-Picado , Ozge Metin Akcan , Isabelle Migeotte , Pierre-Emmanuel Morange , Guillaume Morelle , Andrea Martin-Nalda , Giuseppe Novelli , Antonio Novelli , Tayfun Ozcelik , Figen Palabiyik , Qiang Pan-Hammarström , Rebeca Pérez de Diego , Laura Planas-Serra , Daniel E Pleguezuelo , Carolina Prando , Aurora Pujol , Luis Felipe Reyes , Jacques G Rivière , Carlos Rodriguez-Gallego , Julian Rojas , Patrizia Rovere-Querini , Agatha Schlüter , Mohammad Shahrooei , Ali Sobh , Pere Soler-Palacin , Yacine Tandjaoui-Lambiotte , Imran Tipu , Cristina Tresoldi , Jesus Troya , Diederik van de Beek , Mayana Zatz , Pawel Zawadzki , Saleh Zaid Al-Muhsen , Mohammed Faraj Alosaimi , Fahad M Alsohime , Hagit Baris-Feldman , Manish J Butte , Stefan N Constantinescu , Megan A Cooper , Clifton L Dalgard , Jacques Fellay , James R Heath , Yu-Lung Lau , Richard P Lifton , Tom Maniatis , Trine H Mogensen , Horst von Bernuth , Alban Lermine , Michel Vidaud , Anne Boland , Jean-François Deleuze , Robert Nussbaum , Amanda Kahn-Kirby , France Mentre , Sarah Tubiana , Guy Gorochov , Florence Tubach , Pierre Hausfater , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Isabelle Meyts , Shen-Ying Zhang , Anne Puel , Luigi D Notarangelo , Stephanie Boisson-Dupuis , Helen C Su , Bertrand Boisson , Emmanuelle Jouanguy , Jean-Laurent Casanova , Qian Zhang , Laurent Abel , Aurélie Cobat

Back-to-Africa introductions of Mycobacterium tuberculosis as the main cause of tuberculosis in Dar es Salaam, Tanzania.

PLoS pathogens

Avec: Michaela Zwyer , Liliana K Rutaihwa , Etthel Windels , Jerry Hella , Fabrizio Menardo , Mohamed Sasamalo , Gregor Sommer , Lena Schmülling , Sonia Borrell , Miriam Reinhard , Anna Dötsch , Hellen Hiza , Christoph Stritt , George Sikalengo , Lukas Fenner , Bouke C De Jong , Midori Kato-Maeda , Levan Jugheli , Joel D Ernst , Stefan Niemann , Leila Jeljeli , Marie Ballif , Matthias Egger , Niaina Rakotosamimanana , Dorothy Yeboah-Manu , Prince Asare , Bijaya Malla , Horng Yunn Dou , Nicolas Zetola , Robert J Wilkinson , Helen Cox , E Jane Carter , Joachim Gnokoro , Marcel Yotebieng , Eduardo Gotuzzo , Alash'le Abimiku , Anchalee Avihingsanon , Zhi Ming Xu , Jacques Fellay , Damien Portevin , Klaus Reither , Tanja Stadler , Sebastien Gagneux , Daniela Brites

Association of a Polygenic Risk Score With Osteoporosis in People Living With HIV: The Swiss HIV Cohort Study.

The Journal of infectious diseases

Avec: Johannes M Schwenke , Christian W Thorball , Isabella C Schoepf , Lene Ryom , Barbara Hasse , Olivier Lamy , Alexandra Calmy , Gilles Wandeler , Catia Marzolini , Christian R Kahlert , Enos Bernasconi , Roger D Kouyos , Huldrych F Günthard , Bruno Ledergerber , Jacques Fellay , Felix Burkhalter , Philip E Tarr , Auteur inconnu

Epistatic interaction between ERAP2 and HLA modulates HIV-1 adaptation and disease outcome in an Australian population.

PLoS pathogens

Avec: Marwah Al-Kaabi , Pooja Deshpande , Martin Firth , Rebecca Pavlos , Abha Chopra , Hamed Basiri , Jennifer Currenti , Eric Alves , Spyros Kalams , Jacques Fellay , Elizabeth Phillips , Simon Mallal , Mina John , Silvana Gaudieri

Using viral diversity to identify HIV-1 variants under HLA-dependent selection in a systematic viral genome-wide screen.

PLoS pathogens

Avec: Nadia Neuner-Jehle , Marius Zeeb , Christian W Thorball , Jacques Fellay , Karin J Metzner , Paul Frischknecht , Kathrin Neumann , Christine Leeman , Andri Rauch , Marcel Stöckle , Michael Huber , Matthieu Perreau , Enos Bernasconi , Julia Notter , Matthias Hoffmann , Karoline Leuzinger , Huldrych F Günthard , Chloé Pasin , Roger D Kouyos , Auteur inconnu

Effect of Fc Receptor Genetic Diversity on HIV-1 Disease Pathogenesis.

Frontiers in immunology

Avec: Daniel E Geraghty , Christian W Thorball , Jacques Fellay , Rasmi Thomas

Determinants of HIV-1 reservoir size and long-term dynamics during suppressive ART.

Nature communications

Avec: Nadine Bachmann , Chantal von Siebenthal , Valentina Vongrad , Teja Turk , Kathrin Neumann , Niko Beerenwinkel , Jasmina Bogojeska , Jaques Fellay , Volker Roth , Yik Lim Kok , Christian W Thorball , Alessandro Borghesi , Sonali Parbhoo , Mario Wieser , Jürg Böni , Matthieu Perreau , Thomas Klimkait , Sabine Yerly , Manuel Battegay , Andri Rauch , Matthias Hoffmann , Enos Bernasconi , Matthias Cavassini , Roger D Kouyos , Huldrych F Günthard , Karin J Metzner , Auteur inconnu

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19.

Science (New York, N.Y.)

Avec: Qian Zhang , Paul Bastard , Zhiyong Liu , Jérémie Le Pen , Marcela Moncada-Velez , Jie Chen , Masato Ogishi , Ira K D Sabli , Stephanie Hodeib , Cecilia Korol , Jérémie Rosain , Kaya Bilguvar , Junqiang Ye , Alexandre Bolze , Benedetta Bigio , Rui Yang , Andrés Augusto Arias , Qinhua Zhou , Yu Zhang , Fanny Onodi , Sarantis Korniotis , Léa Karpf , Quentin Philippot , Marwa Chbihi , Lucie Bonnet-Madin , Karim Dorgham , Nikaïa Smith , William M Schneider , Brandon S Razooky , Hans-Heinrich Hoffmann , Eleftherios Michailidis , Leen Moens , Ji Eun Han , Lazaro Lorenzo , Lucy Bizien , Philip Meade , Anna-Lena Neehus , Aileen Camille Ugurbil , Aurélien Corneau , Gaspard Kerner , Peng Zhang , Franck Rapaport , Yoann Seeleuthner , Jeremy Manry , Cecile Masson , Yohann Schmitt , Agatha Schlüter , Tom Le Voyer , Taushif Khan , Juan Li , Jacques Fellay , Lucie Roussel , Mohammad Shahrooei , Mohammed F Alosaimi , Davood Mansouri , Haya Al-Saud , Fahd Al-Mulla , Feras Almourfi , Saleh Zaid Al-Muhsen , Fahad Alsohime , Saeed Al Turki , Rana Hasanato , Diederik van de Beek , Andrea Biondi , Laura Rachele Bettini , Mariella D'Angio' , Paolo Bonfanti , Luisa Imberti , Alessandra Sottini , Simone Paghera , Eugenia Quiros-Roldan , Camillo Rossi , Andrew J Oler , Miranda F Tompkins , Camille Alba , Isabelle Vandernoot , Jean-Christophe Goffard , Guillaume Smits , Isabelle Migeotte , Filomeen Haerynck , Pere Soler-Palacin , Andrea Martin-Nalda , Roger Colobran , Pierre-Emmanuel Morange , Sevgi Keles , Fatma Çölkesen , Tayfun Ozcelik , Kadriye Kart Yasar , Sevtap Senoglu , Şemsi Nur Karabela , Carlos Rodríguez-Gallego , Giuseppe Novelli , Sami Hraiech , Yacine Tandjaoui-Lambiotte , Xavier Duval , Cédric Laouénan , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Andrew L Snow , Clifton L Dalgard , Joshua D Milner , Donald C Vinh , Trine H Mogensen , Nico Marr , András N Spaan , Bertrand Boisson , Stéphanie Boisson-Dupuis , Jacinta Bustamante , Anne Puel , Michael J Ciancanelli , Isabelle Meyts , Tom Maniatis , Vassili Soumelis , Ali Amara , Michel Nussenzweig , Adolfo García-Sastre , Florian Krammer , Aurora Pujol , Darragh Duffy , Richard P Lifton , Shen-Ying Zhang , Guy Gorochov , Vivien Béziat , Emmanuelle Jouanguy , Vanessa Sancho-Shimizu , Charles M Rice , Laurent Abel , Luigi D Notarangelo , Aurélie Cobat , Helen C Su , Jean-Laurent Casanova

SPHN/PHRT - MedCo in Action: Empowering the Swiss Molecular Tumor Board with Privacy-Preserving and Real-Time Patient Discovery.

Studies in health technology and informatics

Avec: Jean Louis Raisaro , Juan Ramòn Troncoso-Pastoriza , Sylvain Pradervand , Michel Cuendet , Mickael Misbach , Joao Sa , Francesco Marino , Nicolas Freundler , Nicolas Rosat , David Cavin , Alexander Leichtle , Jacques Fellay , Olivier Michielin , Jean-Pierre Hubaux

Coronary Artery Disease-Associated and Longevity-Associated Polygenic Risk Scores for Prediction of Coronary Artery Disease Events in Persons Living With Human Immunodeficiency Virus: The Swiss HIV Cohort Study.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Isabella C Schoepf , Christian W Thorball , Bruno Ledergerber , Tanja Engel , Marieke Raffenberg , Neeltje A Kootstra , Peter Reiss , Barbara Hasse , Catia Marzolini , Christine Thurnheer , Marco Seneghini , Enos Bernasconi , Matthias Cavassini , Hélène Buvelot , Roger Kouyos , Huldrych F Günthard , Jacques Fellay , Philip E Tarr , Auteur inconnu

Autoantibodies neutralizing type I IFNs are present in

Science immunology

Avec: Paul Bastard , Adrian Gervais , Tom Le Voyer , Jérémie Rosain , Quentin Philippot , Jérémy Manry , Eleftherios Michailidis , Hans-Heinrich Hoffmann , Shohei Eto , Marina Garcia-Prat , Lucy Bizien , Alba Parra-Martínez , Rui Yang , Liis Haljasmägi , Mélanie Migaud , Karita Särekannu , Julia Maslovskaja , Nicolas de Prost , Yacine Tandjaoui-Lambiotte , Charles-Edouard Luyt , Blanca Amador-Borrero , Alexandre Gaudet , Julien Poissy , Pascal Morel , Pascale Richard , Fabrice Cognasse , Jesus Troya , Sophie Trouillet-Assant , Alexandre Belot , Kahina Saker , Pierre Garçon , Jacques G Rivière , Jean-Christophe Lagier , Stéphanie Gentile , Lindsey B Rosen , Elana Shaw , Tomohiro Morio , Junko Tanaka , David Dalmau , Pierre-Louis Tharaux , Damien Sene , Alain Stepanian , Bruno Megarbane , Vasiliki Triantafyllia , Arnaud Fekkar , James R Heath , José Luis Franco , Juan-Manuel Anaya , Jordi Solé-Violán , Luisa Imberti , Andrea Biondi , Paolo Bonfanti , Riccardo Castagnoli , Ottavia M Delmonte , Yu Zhang , Andrew L Snow , Steven M Holland , Catherine Biggs , Marcela Moncada-Vélez , Andrés Augusto Arias , Lazaro Lorenzo , Soraya Boucherit , Boubacar Coulibaly , Dany Anglicheau , Anna M Planas , Filomeen Haerynck , Sotirija Duvlis , Robert L Nussbaum , Tayfun Ozcelik , Sevgi Keles , Ahmed A Bousfiha , Jalila El Bakkouri , Carolina Ramirez-Santana , Stéphane Paul , Qiang Pan-Hammarström , Lennart Hammarström , Annabelle Dupont , Alina Kurolap , Christine N Metz , Alessandro Aiuti , Giorgio Casari , Vito Lampasona , Fabio Ciceri , Lucila A Barreiros , Elena Dominguez-Garrido , Mateus Vidigal , Mayana Zatz , Diederik van de Beek , Sabina Sahanic , Ivan Tancevski , Yurii Stepanovskyy , Oksana Boyarchuk , Yoko Nukui , Miyuki Tsumura , Loreto Vidaur , Stuart G Tangye , Sonia Burrel , Darragh Duffy , Lluis Quintana-Murci , Adam Klocperk , Nelli Y Kann , Anna Shcherbina , Yu-Lung Lau , Daniel Leung , Matthieu Coulongeat , Julien Marlet , Rutger Koning , Luis Felipe Reyes , Angélique Chauvineau-Grenier , Fabienne Venet , Guillaume Monneret , Michel C Nussenzweig , Romain Arrestier , Idris Boudhabhay , Hagit Baris-Feldman , David Hagin , Joost Wauters , Isabelle Meyts , Adam H Dyer , Sean P Kennelly , Nollaig M Bourke , Rabih Halwani , Narjes Saheb Sharif-Askari , Karim Dorgham , Jérome Sallette , Souad Mehlal Sedkaoui , Suzan AlKhater , Raúl Rigo-Bonnin , Francisco Morandeira , Lucie Roussel , Donald C Vinh , Sisse Rye Ostrowski , Antonio Condino-Neto , Carolina Prando , Anastasiia Bonradenko , András N Spaan , Laurent Gilardin , Jacques Fellay , Stanislas Lyonnet , Kaya Bilguvar , Richard P Lifton , Shrikant Mane , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Mark S Anderson , Bertrand Boisson , Vivien Béziat , Shen-Ying Zhang , Evangelos Vandreakos , Olivier Hermine , Aurora Pujol , Pärt Peterson , Trine H Mogensen , Lee Rowen , James Mond , Stéphanie Debette , Xavier de Lamballerie , Xavier Duval , France Mentré , Marie Zins , Pere Soler-Palacin , Roger Colobran , Guy Gorochov , Xavier Solanich , Sophie Susen , Javier Martinez-Picado , Didier Raoult , Marc Vasse , Peter K Gregersen , Lorenzo Piemonti , Carlos Rodríguez-Gallego , Luigi D Notarangelo , Helen C Su , Kai Kisand , Satoshi Okada , Anne Puel , Emmanuelle Jouanguy , Charles M Rice , Pierre Tiberghien , Qian Zhang , Aurélie Cobat , Laurent Abel , Jean-Laurent Casanova

A highly virulent variant of HIV-1 circulating in the Netherlands.

Science (New York, N.Y.)

Avec: Chris Wymant , Daniela Bezemer , François Blanquart , Luca Ferretti , Astrid Gall , Matthew Hall , Tanya Golubchik , Margreet Bakker , Swee Hoe Ong , Lele Zhao , David Bonsall , Mariateresa de Cesare , George MacIntyre-Cockett , Lucie Abeler-Dörner , Jan Albert , Norbert Bannert , Jacques Fellay , M Kate Grabowski , Barbara Gunsenheimer-Bartmeyer , Huldrych F Günthard , Pia Kivelä , Roger D Kouyos , Oliver Laeyendecker , Laurence Meyer , Kholoud Porter , Matti Ristola , Ard van Sighem , Ben Berkhout , Paul Kellam , Marion Cornelissen , Peter Reiss , Christophe Fraser , Auteur inconnu , Auteur inconnu

Telomere Length Declines in Persons With Human Immunodeficiency Virus Before Antiretroviral Therapy Start but Not After Viral Suppression: A Longitudinal Study Over >17 Years.

The Journal of infectious diseases

Avec: Isabella C Schoepf , Christian W Thorball , Bruno Ledergerber , Neeltje A Kootstra , Peter Reiss , Marieke Raffenberg , Tanja Engel , Dominique L Braun , Barbara Hasse , Christine Thurnheer , Catia Marzolini , Marco Seneghini , Enos Bernasconi , Matthias Cavassini , Hélène Buvelot , José R Arribas , Roger D Kouyos , Jacques Fellay , Huldrych F Günthard , Philip E Tarr

Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load.

Virus evolution

Avec: Lele Zhao , Chris Wymant , François Blanquart , Tanya Golubchik , Astrid Gall , Margreet Bakker , Daniela Bezemer , Matthew Hall , Swee Hoe Ong , Jan Albert , Norbert Bannert , Jacques Fellay , M Kate Grabowski , Barbara Gunsenheimer-Bartmeyer , Huldrych F Günthard , Pia Kivelä , Roger D Kouyos , Oliver Laeyendecker , Laurence Meyer , Kholoud Porter , Ard van Sighem , Marc van der Valk , Ben Berkhout , Paul Kellam , Marion Cornelissen , Peter Reiss , Christophe Fraser , Luca Ferretti

The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Jérémy Manry , Paul Bastard , Adrian Gervais , Tom Le Voyer , Jérémie Rosain , Quentin Philippot , Eleftherios Michailidis , Hans-Heinrich Hoffmann , Shohei Eto , Marina Garcia-Prat , Lucy Bizien , Alba Parra-Martínez , Rui Yang , Liis Haljasmägi , Mélanie Migaud , Karita Särekannu , Julia Maslovskaja , Nicolas de Prost , Yacine Tandjaoui-Lambiotte , Charles-Edouard Luyt , Blanca Amador-Borrero , Alexandre Gaudet , Julien Poissy , Pascal Morel , Pascale Richard , Fabrice Cognasse , Jesús Troya , Sophie Trouillet-Assant , Alexandre Belot , Kahina Saker , Pierre Garçon , Jacques G Rivière , Jean-Christophe Lagier , Stéphanie Gentile , Lindsey B Rosen , Elana Shaw , Tomohiro Morio , Junko Tanaka , David Dalmau , Pierre-Louis Tharaux , Damien Sene , Alain Stepanian , Bruno Mégarbane , Vasiliki Triantafyllia , Arnaud Fekkar , James R Heath , José Luis Franco , Juan-Manuel Anaya , Jordi Solé-Violán , Luisa Imberti , Andrea Biondi , Paolo Bonfanti , Riccardo Castagnoli , Ottavia M Delmonte , Yu Zhang , Andrew L Snow , Steven M Holland , Catherine M Biggs , Marcela Moncada-Vélez , Andrés Augusto Arias , Lazaro Lorenzo , Soraya Boucherit , Dany Anglicheau , Anna M Planas , Filomeen Haerynck , Sotirija Duvlis , Tayfun Ozcelik , Sevgi Keles , Ahmed A Bousfiha , Jalila El Bakkouri , Carolina Ramirez-Santana , Stéphane Paul , Qiang Pan-Hammarström , Lennart Hammarström , Annabelle Dupont , Alina Kurolap , Christine N Metz , Alessandro Aiuti , Giorgio Casari , Vito Lampasona , Fabio Ciceri , Lucila A Barreiros , Elena Dominguez-Garrido , Mateus Vidigal , Mayana Zatz , Diederik van de Beek , Sabina Sahanic , Ivan Tancevski , Yurii Stepanovskyy , Oksana Boyarchuk , Yoko Nukui , Miyuki Tsumura , Loreto Vidaur , Stuart G Tangye , Sonia Burrel , Darragh Duffy , Lluis Quintana-Murci , Adam Klocperk , Nelli Y Kann , Anna Shcherbina , Yu-Lung Lau , Daniel Leung , Matthieu Coulongeat , Julien Marlet , Rutger Koning , Luis Felipe Reyes , Angélique Chauvineau-Grenier , Fabienne Venet , Guillaume Monneret , Michel C Nussenzweig , Romain Arrestier , Idris Boudhabhay , Hagit Baris-Feldman , David Hagin , Joost Wauters , Isabelle Meyts , Adam H Dyer , Sean P Kennelly , Nollaig M Bourke , Rabih Halwani , Fatemeh Saheb Sharif-Askari , Karim Dorgham , Jérôme Sallette , Souad Mehlal Sedkaoui , Suzan AlKhater , Raúl Rigo-Bonnin , Francisco Morandeira , Lucie Roussel , Donald C Vinh , Christian Erikstrup , Antonio Condino-Neto , Carolina Prando , Anastasiia Bondarenko , András N Spaan , Laurent Gilardin , Jacques Fellay , Stanislas Lyonnet , Kaya Bilguvar , Richard P Lifton , Shrikant Mane , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Mark S Anderson , Bertrand Boisson , Vivien Béziat , Shen-Ying Zhang , Evangelos Andreakos , Olivier Hermine , Aurora Pujol , Pärt Peterson , Trine H Mogensen , Lee Rowen , James Mond , Stéphanie Debette , Xavier de Lamballerie , Charles Burdet , Lila Bouadma , Marie Zins , Pere Soler-Palacin , Roger Colobran , Guy Gorochov , Xavier Solanich , Sophie Susen , Javier Martinez-Picado , Didier Raoult , Marc Vasse , Peter K Gregersen , Lorenzo Piemonti , Carlos Rodríguez-Gallego , Luigi D Notarangelo , Helen C Su , Kai Kisand , Satoshi Okada , Anne Puel , Emmanuelle Jouanguy , Charles M Rice , Pierre Tiberghien , Qian Zhang , Jean-Laurent Casanova , Laurent Abel , Aurélie Cobat

Visual masking deficits in schizophrenia: a view into the genetics of the disease through an endophenotype.

Translational psychiatry

Avec: Albulena Shaqiri , Flavia Hodel , Janir Ramos da Cruz , Maya Roinishvili , Eka Chkonia , Andreas Brand , Jacques Fellay , Michael H Herzog

Africa-specific human genetic variation near CHD1L associates with HIV-1 load.

Nature

Avec: Paul J McLaren , Immacolata Porreca , Gennaro Iaconis , Hoi Ping Mok , Subhankar Mukhopadhyay , Emre Karakoc , Sara Cristinelli , Cristina Pomilla , István Bartha , Christian W Thorball , Riley H Tough , Paolo Angelino , Cher S Kiar , Tommy Carstensen , Segun Fatumo , Tarryn Porter , Isobel Jarvis , William C Skarnes , Andrew Bassett , Marianne K DeGorter , Mohana Prasad Sathya Moorthy , Jeffrey F Tuff , Eun-Young Kim , Miriam Walter , Lacy M Simons , Arman Bashirova , Susan Buchbinder , Mary Carrington , Andrea Cossarizza , Andrea De Luca , James J Goedert , David B Goldstein , David W Haas , Joshua T Herbeck , Eric O Johnson , Pontiano Kaleebu , William Kilembe , Gregory D Kirk , Neeltje A Kootstra , Alex H Kral , Olivier Lambotte , Ma Luo , Simon Mallal , Javier Martinez-Picado , Laurence Meyer , José M Miro , Pravi Moodley , Ayesha A Motala , James I Mullins , Kireem Nam , Niels Obel , Fraser Pirie , Francis A Plummer , Guido Poli , Matthew A Price , Andri Rauch , Ioannis Theodorou , Alexandra Trkola , Bruce D Walker , Cheryl A Winkler , Jean-François Zagury , Stephen B Montgomery , Angela Ciuffi , Judd F Hultquist , Steven M Wolinsky , Gordon Dougan , Andrew M L Lever , Deepti Gurdasani , Harriet Groom , Manjinder S Sandhu , Jacques Fellay

Genetic features and genomic targets of human KRAB-zinc finger proteins.

Genome research

Avec: Jonas de Tribolet-Hardy , Christian W Thorball , Romain Forey , Evarist Planet , Julien Duc , Alexandre Coudray , Bara Khubieh , Sandra Offner , Cyril Pulver , Jacques Fellay , Michael Imbeault , Priscilla Turelli , Didier Trono

The

Frontiers in immunology

Avec: Myriam Rahmouni , Lorenzo De Marco , Jean-Louis Spadoni , Maxime Tison , Raissa Medina-Santos , Taoufik Labib , Josselin Noirel , Ryad Tamouza , Sophie Limou , Olivier Delaneau , Jacques Fellay , Armand Bensussan , Sigrid Le Clerc , Paul J McLaren , Jean-François Zagury

Diagnostic accuracy of a sequence-specific

Microbiology spectrum

Avec: Yves Tschan , Mohamed Sasamalo , Hellen Hiza , Jacques Fellay , Sébastien Gagneux , Klaus Reither , Jerry Hella , Damien Portevin

Prevalence of actionable pharmacogenetic variants and high-risk drug prescriptions: A Swiss hospital-based cohort study.

Clinical and translational science

Avec: Flavia Hodel , Maria B De Min , Christian Wandall Thorball , Claire Redin , Peter Vollenweider , François Girardin , Jacques Fellay

Host Genomics of the HIV-1 Reservoir Size and Its Decay Rate During Suppressive Antiretroviral Treatment.

Journal of acquired immune deficiency syndromes (1999)

Avec: Christian W Thorball , Alessandro Borghesi , Nadine Bachmann , Chantal Von Siebenthal , Valentina Vongrad , Teja Turk , Kathrin Neumann , Niko Beerenwinkel , Jasmina Bogojeska , Volker Roth , Yik Lim Kok , Sonali Parbhoo , Mario Wieser , Jürg Böni , Matthieu Perreau , Thomas Klimkait , Sabine Yerly , Manuel Battegay , Andri Rauch , Patrick Schmid , Enos Bernasconi , Matthias Cavassini , Roger D Kouyos , Huldrych F Günthard , Karin J Metzner , Jacques Fellay , Auteur inconnu

Revolutionizing Medical Data Sharing Using Advanced Privacy-Enhancing Technologies: Technical, Legal, and Ethical Synthesis.

Journal of medical Internet research

Avec: James Scheibner , Jean Louis Raisaro , Juan Ramón Troncoso-Pastoriza , Marcello Ienca , Jacques Fellay , Effy Vayena , Jean-Pierre Hubaux

Impact of Delaying Antiretroviral Treatment During Primary Human Immunodeficiency Virus Infection on Telomere Length.

The Journal of infectious diseases

Avec: Marieke Raffenberg , Tanja Engel , Isabella C Schoepf , Neeltje A Kootstra , Peter Reiss , Dominique L Braun , Christian W Thorball , Jacques Fellay , Roger D Kouyos , Bruno Ledergerber , Huldrych F Günthard , Philip E Tarr , Auteur inconnu , Auteur inconnu

Immunological lessons from genome-wide association studies of infections.

Current opinion in immunology

Avec: Christian W Thorball , Jacques Fellay , Alessandro Borghesi

HIV Transmission Chains Exhibit Greater HLA-B Homogeneity Than Randomly Expected.

Journal of acquired immune deficiency syndromes (1999)

Avec: Huyen Nguyen , Christian W Thorball , Jacques Fellay , Jürg Böni , Sabine Yerly , Matthieu Perreau , Thomas Klimkait , Katharina Kusejko , Nadine Bachmann , Sandra E Chaudron , Paolo Paioni , Maria C Thurnheer , Manuel Battegay , Matthias Cavassini , Pietro Vernazza , Enos Bernasconi , Huldrych F Günthard , Roger Kouyos , Auteur inconnu

Telomere Length, Traditional Risk Factors, Factors Related to Human Immunodeficiency Virus (HIV) and Coronary Artery Disease Events in Swiss Persons Living With HIV.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Tanja Engel , Marieke Raffenberg , Isabella C Schoepf , Neeltje A Kootstra , Peter Reiss , Christian W Thorball , Barbara Hasse , Cédric Hirzel , Kerstin Wissel , Jan A Roth , Enos Bernasconi , Katharine E A Darling , Alexandra Calmy , Jacques Fellay , Roger D Kouyos , Huldrych F Günthard , Bruno Ledergerber , Philip E Tarr , Auteur inconnu

Data protection and ethics requirements for multisite research with health data: a comparative examination of legislative governance frameworks and the role of data protection technologies.

Journal of law and the biosciences

Avec: James Scheibner , Marcello Ienca , Sotiria Kechagia , Juan Ramon Troncoso-Pastoriza , Jean Louis Raisaro , Jean-Pierre Hubaux , Jacques Fellay , Effy Vayena

Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure.

Nature communications

Avec: David A Smith , Carlota Fernandez-Antunez , Andrea Magri , Rory Bowden , Nimisha Chaturvedi , Jacques Fellay , John McLauchlan , Graham R Foster , William L Irving , Auteur inconnu , Peter Simmonds , Vincent Pedergnana , Santseharay Ramirez , Jens Bukh , Eleanor Barnes , M Azim Ansari

Human genomics of the humoral immune response against polyomaviruses.

Virus evolution

Avec: F Hodel , A Y Chong , P Scepanovic , Z M Xu , O Naret , C W Thorball , S Rüeger , P Marques-Vidal , P Vollenweider , M Begemann , H Ehrenreich , N Brenner , N Bender , T Waterboer , A J Mentzer , A V S Hill , C Hammer , J Fellay

Using population-specific add-on polymorphisms to improve genotype imputation in underrepresented populations.

PLoS computational biology

Avec: Zhi Ming Xu , Sina Rüeger , Michaela Zwyer , Daniela Brites , Hellen Hiza , Miriam Reinhard , Liliana Rutaihwa , Sonia Borrell , Faima Isihaka , Hosiana Temba , Thomas Maroa , Rastard Naftari , Jerry Hella , Mohamed Sasamalo , Klaus Reither , Damien Portevin , Sebastien Gagneux , Jacques Fellay

Host genomics of SARS-CoV-2 infection.

European journal of human genetics : EJHG

Avec: Claire Redin , Christian W Thorball , Jacques Fellay

Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania.

Scientific reports

Avec: Hellen Hiza , Michaela Zwyer , Jerry Hella , Ainhoa Arbués , Mohamed Sasamalo , Sonia Borrell , Zhi Ming Xu , Amanda Ross , Daniela Brites , Jacques Fellay , Klaus Reither , Sébastien Gagneux , Damien Portevin

Self-reported neurocognitive complaints in the Swiss HIV Cohort Study: a viral genome-wide association study.

Brain communications

Avec: Marius Zeeb , Chloé Pasin , Matthias Cavassini , Mélanie Bieler-Aeschlimann , Paul Frischknecht , Katharina Kusejko , Jacques Fellay , François Blanquart , Karin J Metzner , Kathrin Neumann , Lisa Jörimann , Jasmin Tschumi , Enos Bernasconi , Michael Huber , Helen Kovari , Karoline Leuzinger , Julia Notter , Matthieu Perreau , Andri Rauch , Alban Ramette , Marcel Stöckle , Sabine Yerly , Huldrych F Günthard , Roger D Kouyos , Auteur inconnu

Loss of tolerance precedes triggering and lifelong persistence of pathogenic type I interferon autoantibodies.

The Journal of experimental medicine

Avec: Sonja Fernbach , Nina K Mair , Irene A Abela , Kevin Groen , Roger Kuratli , Marie Lork , Christian W Thorball , Enos Bernasconi , Paraskevas Filippidis , Karoline Leuzinger , Julia Notter , Andri Rauch , Hans H Hirsch , Michael Huber , Huldrych F Günthard , Jacques Fellay , Roger D Kouyos , Benjamin G Hale , Auteur inconnu

The «Amish» NM_000256.3:c.3330+2T>G splice variant in MYBPC3 associated with hypertrophic cardiomyopathy is an ancient Swiss mutation.

European journal of medical genetics

Avec: Claire Redin , Despina Christina Pavlidou , Zahurul Bhuiyan , Alessandra Pia Porretta , Pierre Monney , Nicola Bedoni , Fabienne Maurer , Nicole Sekarski , Isis Atallah , Davoine Émeline , Xavier Jeanrenaud , Etienne Pruvot , Jacques Fellay , Andrea Superti-Furga

Viral Genetic Determinants of Prolonged Respiratory Syncytial Virus Infection Among Infants in a Healthy Term Birth Cohort.

The Journal of infectious diseases

Avec: Dylan Lawless , Christopher G McKennan , Suman R Das , Thomas Junier , Zhi Ming Xu , Larry J Anderson , Tebeb Gebretsadik , Meghan H Shilts , Emma Larkin , Christian Rosas-Salazar , James D Chappell , Jacques Fellay , Tina V Hartert

Autoantibodies neutralizing type I IFNs underlie West Nile virus encephalitis in ∼40% of patients.

The Journal of experimental medicine

Avec: Adrian Gervais , Francesca Rovida , Maria Antonietta Avanzini , Stefania Croce , Astrid Marchal , Shih-Ching Lin , Alessandro Ferrari , Christian W Thorball , Orianne Constant , Tom Le Voyer , Quentin Philippot , Jérémie Rosain , Micol Angelini , Malena Pérez Lorenzo , Lucy Bizien , Cristian Achille , Francesca Trespidi , Elisa Burdino , Irene Cassaniti , Daniele Lilleri , Chiara Fornara , José Camilla Sammartino , Danilo Cereda , Chiara Marrocu , Antonio Piralla , Chiara Valsecchi , Stefano Ricagno , Paola Cogo , Olaf Neth , Inés Marín-Cruz , Monia Pacenti , Alessandro Sinigaglia , Marta Trevisan , Andrea Volpe , Antonio Marzollo , Francesca Conti , Tiziana Lazzarotto , Andrea Pession , Pierluigi Viale , Jacques Fellay , Stefano Ghirardello , Mélodie Aubart , Valeria Ghisetti , Alessandro Aiuti , Emmanuelle Jouanguy , Paul Bastard , Elena Percivalle , Fausto Baldanti , Anne Puel , Margaret R MacDonald , Charles M Rice , Giada Rossini , Kristy O Murray , Yannick Simonin , Anna Nagy , Luisa Barzon , Laurent Abel , Michael S Diamond , Aurélie Cobat , Shen-Ying Zhang , Jean-Laurent Casanova , Alessandro Borghesi

A metagenome-wide association study of HIV disease progression in HIV controllers.

iScience

Avec: Luis Miguel Real , María E Sáez , Anais Corma-Gómez , Antonio Gonzalez-Pérez , Christian Thorball , Rocío Ruiz , María Reyes Jimenez-Leon , Alejandro Gonzalez-Serna , Carmen Gasca-Capote , María José Bravo , José Luis Royo , Alberto Perez-Gomez , María Inés Camacho-Sojo , Isabel Gallego , Joana Vitalle , Sara Bachiller , Alicia Gutierrez-Valencia , Francisco Vidal , Jacques Fellay , Mathias Lichterfeld , Ezequiel Ruiz-Mateos , Auteur inconnu

Lack of association between HLA and asymptomatic SARS-CoV-2 infection.

medRxiv : the preprint server for health sciences

Avec: Astrid Marchal , Elizabeth T Cirulli , Iva Neveux , Evangelos Bellos , Ryan S Thwaites , Kelly M Schiabor Barrett , Yu Zhang , Ivana Nemes-Bokun , Mariya Kalinova , Andrew Catchpole , Stuart G Tangye , András N Spaan , Justin B Lack , Jade Ghosn , Charles Burdet , Guy Gorochov , Florence Tubach , Pierre Hausfater , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Clifton L Dalgard , Shen-Ying Zhang , Qian Zhang , Christopher Chiu , Jacques Fellay , Joseph J Grzymski , Vanessa Sancho-Shimizu , Laurent Abel , Jean-Laurent Casanova , Aurélie Cobat , Alexandre Bolze

Weight, anthropometric and metabolic changes after discontinuing antiretroviral therapy containing tenofovir alafenamide (TAF) in people with HIV.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: José Damas , Aline Munting , Jacques Fellay , David Haerry , Catia Marzolini , Philip E Tarr , Ana Steffen , Dominique L Braun , Marcel Stoeckle , Enos Bernasconi , Olivier Nawej Tshikung , Christoph A Fux , Katharine E A Darling , Charles Béguelin , Gilles Wandeler , Matthias Cavassini , Bernard Surial , Auteur inconnu

Genetic variation near CXCL12 is associated with susceptibility to HIV-related non-Hodgkin lymphoma.

Haematologica

Avec: Christian W Thorball , Tiphaine Oudot-Mellakh , Nava Ehsan , Christian Hammer , Federico A Santoni , Jonathan Niay , Dominique Costagliola , Cécile Goujard , Laurence Meyer , Sophia S Wang , Shehnaz K Hussain , Ioannis Theodorou , Matthias Cavassini , Andri Rauch , Manuel Battegay , Matthias Hoffmann , Patrick Schmid , Enos Bernasconi , Huldrych F Günthard , Pejman Mohammadi , Paul J McLaren , Charles S Rabkin , Caroline Besson , Jacques Fellay

Susceptibility to infection in early life: a growing role for human genetics.

Human genetics

Avec: Alessandro Borghesi , Antonio Marzollo , Alexandre Michev , Jacques Fellay

[Precision medicine : at the crossroad of molecular biology, information sciences and humanities].

Revue medicale suisse

Avec: Romain-Daniel Gosselin , Claire Redin , Élodie Ristorcelli , Jean Louis Raisaro , Jacques Fellay

Impact of Genetic and Nongenetic Factors on Body Mass Index and Waist-Hip Ratio Change in HIV-Infected Individuals Initiating Antiretroviral Therapy.

Open forum infectious diseases

Avec: Catalina Barceló , Monia Guidi , Christian W Thorball , Christian Hammer , Aziz Chaouch , Alexandra U Scherrer , Barbara Hasse , Matthias Cavassini , Hansjakob Furrer , Alexandra Calmy , Sebastian Haubitz , Enos Bernasconi , Thierry Buclin , Jacques Fellay , Philip E Tarr , Chantal Csajka , Auteur inconnu

Viral Metagenomics in the Clinical Realm: Lessons Learned from a Swiss-Wide Ring Trial.

Genes

Avec: Thomas Junier , Michael Huber , Stefan Schmutz , Verena Kufner , Osvaldo Zagordi , Stefan Neuenschwander , Alban Ramette , Jakub Kubacki , Claudia Bachofen , Weihong Qi , Florian Laubscher , Samuel Cordey , Laurent Kaiser , Christian Beuret , Valérie Barbié , Jacques Fellay , Aitana Lebrand

Predicting the Occurrence of Variants in RAG1 and RAG2.

Journal of clinical immunology

Avec: Dylan Lawless , Hana Lango Allen , James Thaventhiran , Auteur inconnu , Flavia Hodel , Rashida Anwar , Jacques Fellay , Jolan E Walter , Sinisa Savic

Gender medicine and oncology: report and consensus of an ESMO workshop.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: A D Wagner , S Oertelt-Prigione , A Adjei , T Buclin , V Cristina , C Csajka , G Coukos , U Dafni , G-P Dotto , M Ducreux , J Fellay , J Haanen , A Hocquelet , I Klinge , V Lemmens , A Letsch , M Mauer , M Moehler , S Peters , B C Özdemir

HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Jatin Arora , Paul J McLaren , Nimisha Chaturvedi , Mary Carrington , Jacques Fellay , Tobias L Lenz

The influence of human genetic variation on Epstein-Barr virus sequence diversity.

Scientific reports

Avec: Sina Rüeger , Christian Hammer , Alexis Loetscher , Paul J McLaren , Dylan Lawless , Olivier Naret , Nina Khanna , Enos Bernasconi , Matthias Cavassini , Huldrych F Günthard , Christian R Kahlert , Andri Rauch , Daniel P Depledge , Sofia Morfopoulou , Judith Breuer , Evgeny Zdobnov , Jacques Fellay , Auteur inconnu

The risk of COVID-19 death is much greater and age-dependent with type I IFN autoantibodies.

Research square

Avec: Jeremy Manry , Paul Bastard , Adrian Gervais , Tom Le Voyer , Jérémie Rosain , Quentin Philippot , Eleftherios Michailidis , Hans-Heinrich Hoffmann , Shohei Eto , Marina Garcia-Prat , Lucy Bizien , Alba Parra-Martínez , Rui Yang , Liis Haljasmägi , Mélanie Migaud , Karita Särekannu , Julia Maslovskaja , Nicolas de Prost , Yacine Tandjaoui-Lambiotte , Charles-Edouard Luyt , Blanca Amador-Borrero , Alexandre Gaudet , Julien Poissy , Pascal Morel , Pascale Richard , Fabrice Cognasse , Jesus Troya , Sophie Trouillet-Assant , Alexandre Belot , Kahina Saker , Pierre Garçon , Jacques G Rivière , Jean-Christophe Lagier , Stéphanie Gentile , Lindsey Rosen , Elana Shaw , Tomohiro Morio , Junko Tanaka , David Dalmau , Pierre-Louis Tharaux , Damien Sene , Alain Stepanian , Bruno Mégarbane , Vasiliki Triantafyllia , Arnaud Fekkar , James Heath , Jose Franco , Juan-Manuel Anaya , Jordi Solé-Violán , Luisa Imberti , Andrea Biondi , Paolo Bonfanti , Riccardo Castagnoli , Ottavia Delmonte , Yu Zhang , Andrew Snow , Steve Holland , Catherine Biggs , Marcela Moncada-Vélez , Andrés Arias , Lazaro Lorenzo , Soraya Boucherit , Dany Anglicheau , Anna Planas , Filomeen Haerynck , Sotirija Duvlis , Robert Nussbaum , Tayfun Ozcelik , Sevgi Keles , Aziz Bousfiha , Jalila El Bakkouri , Carolina Ramirez-Santana , Stéphane Paul , Qiang Pan-Hammarstrom , Lennart Hammarstrom , Annabelle Dupont , Alina Kurolap , Christine Metz , Alessandro Aiuti , Giorgio Casari , Vito Lampasona , Fabio Ciceri , Lucila Barreiros , Elena Dominguez-Garrido , Mateus Vidigal , Mayana Zatz , Diederik van de Beek , Sabina Sahanic , Ivan Tancevski , Yurii Stepanovskyy , Oksana Boyarchuk , Yoko Nukui , Miyuki Tsumura , Loreto Vidaur , Stuart Tangye , Sonia Burrel , Darragh Duffy , Lluis Quintana-Murci , Adam Klocperk , Nelli Kann , Anna Shcherbina , Yu-Lung Lau , Daniel Leung , Matthieu Coulongeat , Julien Marlet , Rutger Koning , Luis Reyes , Angélique Chauvineau-Grenier , Fabienne Venet , Guillaume Monneret , Michel Nussenzweig , Romain Arrestier , Idris Boudhabhay , Hagit Baris-Feldman , David Hagin , Joost Wauters , Isabelle Meyts , Adam Dyer , Sean Kennelly , Nollaig Bourke , Rabih Halwani , Fatemeh Sharif-Askari , Karim Dorgham , Jérôme Sallette , Souad Mehlal-Sedkaoui , Suzan AlKhater , Raúl Rigo-Bonnin , Francisco Morandeira , Lucie Roussel , Donald Vinh , Christian Erikstrup , Antonio Condino-Neto , Carolina Prando , Anastasiia Bondarenko , András Spaan , Laurent Gilardin , Jacques Fellay , Stanislas Lyonnet , Kaya Bilguvar , Richard Lifton , Shrikant Mane , Mark Anderson , Bertrand Boisson , Vivien Béziat , Shen-Ying Zhang , Evangelos Andreakos , Olivier Hermine , Aurora Pujol , Pärt Peterson , Trine Hyrup Mogensen , Lee Rowen , James Mond , Stéphanie Debette , Xavier deLamballerie , Charles Burdet , Lila Bouadma , Marie Zins , Pere Soler-Palacin , Roger Colobran , Guy Gorochov , Xavier Solanich , Sophie Susen , Javier Martinez-Picado , Didier Raoult , Marc Vasse , Peter Gregersen , Carlos Rodríguez-Gallego , Lorenzo Piemonti , Luigi Notarangelo , Helen Su , Kai Kisand , Satoshi Okada , Anne Puel , Emmanuelle Jouanguy , Charles Rice , Pierre Tiberghien , Qian Zhang , Jean-Laurent Casanova , Laurent Abel , Aurélie Cobat

Increased prevalence of clonal hematopoiesis of indeterminate potential amongst people living with HIV.

Scientific reports

Avec: Alexander G Bick , Konstantin Popadin , Christian W Thorball , Md Mesbah Uddin , Markella V Zanni , Bing Yu , Matthias Cavassini , Andri Rauch , Philip Tarr , Patrick Schmid , Enos Bernasconi , Huldrych F Günthard , Peter Libby , Eric Boerwinkle , Paul J McLaren , Christie M Ballantyne , Steven Grinspoon , Pradeep Natarajan , Jacques Fellay , Auteur inconnu

Blood virosphere in febrile Tanzanian children.

Emerging microbes & infections

Avec: Samuel Cordey , Florian Laubscher , Mary-Anne Hartley , Thomas Junier , Kristina Keitel , Mylène Docquier , Nicolas Guex , Christian Iseli , Gael Vieille , Philippe Le Mercier , Anne Gleizes , Josephine Samaka , Tarsis Mlaganile , Frank Kagoro , John Masimba , Zamzam Said , Hosiana Temba , Gasser H Elbanna , Caroline Tapparel , Marie-Celine Zanella , Ioannis Xenarios , Jacques Fellay , Valérie D'Acremont , Laurent Kaiser

Dissemination of

Journal of extracellular vesicles

Avec: Susana Benet , Cristina Gálvez , Francis Drobniewski , Irina Kontsevaya , Lilibeth Arias , Marta Monguió-Tortajada , Itziar Erkizia , Victor Urrea , Ruo-Yan Ong , Marina Luquin , Maeva Dupont , Jakub Chojnacki , Judith Dalmau , Paula Cardona , Olivier Neyrolles , Geanncarlo Lugo-Villarino , Christel Vérollet , Esther Julián , Hansjakob Furrer , Huldrych F Günthard , Paul R Crocker , Gustavo Tapia , Francesc E Borràs , Jacques Fellay , Paul J McLaren , Amalio Telenti , Pere-Joan Cardona , Bonaventura Clotet , Cristina Vilaplana , Javier Martinez-Picado , Nuria Izquierdo-Useros

Improving polygenic prediction with genetically inferred ancestry.

HGG advances

Avec: Olivier Naret , Zoltan Kutalik , Flavia Hodel , Zhi Ming Xu , Pedro Marques-Vidal , Jacques Fellay

HIV-1 and human genetic variation.

Nature reviews. Genetics

Avec: Paul J McLaren , Jacques Fellay

Predicting type 2 diabetes risk before and after solid organ transplantation using polygenic scores in a Danish cohort.

Frontiers in molecular biosciences

Avec: Quenia Dos Santos , Preston Leung , Christian W Thorball , Bruno Ledergerber , Jacques Fellay , Cameron R MacPherson , Mads Hornum , Cynthia Terrones-Campos , Allan Rasmussen , Finn Gustafsson , Michael Perch , Søren S Sørensen , Christina Ekenberg , Jens D Lundgren , Bo Feldt-Rasmussen , Joanne Reekie

Epigenetic ageing accelerates before antiretroviral therapy and decelerates after viral suppression in people with HIV in Switzerland: a longitudinal study over 17 years.

The lancet. Healthy longevity

Avec: Isabella C Schoepf , Andrés Esteban-Cantos , Christian W Thorball , Berta Rodés , Peter Reiss , Javier Rodríguez-Centeno , Carlotta Riebensahm , Dominique L Braun , Catia Marzolini , Marco Seneghini , Enos Bernasconi , Matthias Cavassini , Hélène Buvelot , Maria Christine Thurnheer , Roger D Kouyos , Jacques Fellay , Huldrych F Günthard , José R Arribas , Bruno Ledergerber , Philip E Tarr , Auteur inconnu

Human Genomics of COVID-19 Pneumonia: Contributions of Rare and Common Variants.

Annual review of biomedical data science

Avec: Aurélie Cobat , Qian Zhang , Auteur inconnu , Laurent Abel , Jean-Laurent Casanova , Jacques Fellay

Multiancestry sex-stratified genomic associations with HIV viral load and controller status from the ICGH.

JCI insight

Avec: Candelaria Vergara , Jeffrey F Tuff , Auteur inconnu , Jacques Fellay , Priya Duggal , Eileen P Scully , Paul J McLaren

Citizen-centered, auditable and privacy-preserving population genomics.

Nature computational science

Avec: Dennis Grishin , Jean Louis Raisaro , Juan Ramón Troncoso-Pastoriza , Kamal Obbad , Kevin Quinn , Mickaël Misbach , Jared Gollhardt , Joao Sa , Jacques Fellay , George M Church , Jean-Pierre Hubaux

Combining European and U.S. risk prediction models with polygenic risk scores to refine cardiovascular prevention: the CoLaus|PsyCoLaus Study.

European journal of preventive cardiology

Avec: Roxane de La Harpe , Christian W Thorball , Claire Redin , Stephane Fournier , Olivier Müller , Davide Strambo , Patrik Michel , Peter Vollenweider , Pedro Marques-Vidal , Jacques Fellay , Julien Vaucher

A common NFKB1 variant detected through antibody analysis in UK Biobank predicts risk of infection and allergy.

American journal of human genetics

Avec: Amanda Y Chong , Nicole Brenner , Andres Jimenez-Kaufmann , Adrian Cortes , Michael Hill , Thomas J Littlejohns , James J Gilchrist , Benjamin P Fairfax , Julian C Knight , Flavia Hodel , Jacques Fellay , Gil McVean , Andres Moreno-Estrada , Tim Waterboer , Adrian V S Hill , Alexander J Mentzer

Exploring the interactions between the human and viral genomes.

Human genetics

Avec: Jacques Fellay , Vincent Pedergnana

HLA Heterozygote Advantage against HIV-1 Is Driven by Quantitative and Qualitative Differences in HLA Allele-Specific Peptide Presentation.

Molecular biology and evolution

Avec: Jatin Arora , Federica Pierini , Paul J McLaren , Mary Carrington , Jacques Fellay , Tobias L Lenz

Contribution of Genetic Background and Data Collection on Adverse Events of Anti-human Immunodeficiency Virus (HIV) Drugs (D:A:D) Clinical Risk Score to Chronic Kidney Disease in Swiss HIV-infected Persons With Normal Baseline Estimated Glomerular Filtration Rate.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Léna G Dietrich , Catalina Barceló , Christian W Thorball , Lene Ryom , Felix Burkhalter , Barbara Hasse , Hansjakob Furrer , Maja Weisser , Ana Steffen , Enos Bernasconi , Matthias Cavassini , Sophie de Seigneux , Chantal Csajka , Jacques Fellay , Bruno Ledergerber , Philip E Tarr

Adaptation of hepatitis C virus to interferon lambda polymorphism across multiple viral genotypes.

eLife

Avec: Nimisha Chaturvedi , Evguenia S Svarovskaia , Hongmei Mo , Anu O Osinusi , Diana M Brainard , G Mani Subramanian , John G McHutchison , Stefan Zeuzem , Jacques Fellay

HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses.

eLife

Avec: Simon Langer , Christian Hammer , Kristina Hopfensperger , Lukas Klein , Dominik Hotter , Paul D De Jesus , Kristina M Herbert , Lars Pache , Nikaïa Smith , Johannes A van der Merwe , Sumit K Chanda , Jacques Fellay , Frank Kirchhoff , Daniel Sauter

Human genomics of acute liver failure due to hepatitis B virus infection: An exome sequencing study in liver transplant recipients.

Journal of viral hepatitis

Avec: Samira Asgari , Nimisha Chaturvedi , Petar Scepanovic , Christian Hammer , Nasser Semmo , Emiliano Giostra , Beat Müllhaupt , Peter Angus , Alexander J Thompson , Darius Moradpour , Jacques Fellay

A comprehensive assessment of demographic, environmental, and host genetic associations with gut microbiome diversity in healthy individuals.

Microbiome

Avec: Petar Scepanovic , Flavia Hodel , Stanislas Mondot , Valentin Partula , Allyson Byrd , Christian Hammer , Cécile Alanio , Jacob Bergstedt , Etienne Patin , Mathilde Touvier , Olivier Lantz , Matthew L Albert , Darragh Duffy , Lluis Quintana-Murci , Jacques Fellay , Auteur inconnu

Truly privacy-preserving federated analytics for precision medicine with multiparty homomorphic encryption.

Nature communications

Avec: David Froelicher , Juan R Troncoso-Pastoriza , Jean Louis Raisaro , Michel A Cuendet , Joao Sa Sousa , Hyunghoon Cho , Bonnie Berger , Jacques Fellay , Jean-Pierre Hubaux

HLA tapasin independence: broader peptide repertoire and HIV control.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Arman A Bashirova , Mathias Viard , Vivek Naranbhai , Alba Grifoni , Wilfredo Garcia-Beltran , Marjan Akdag , Yuko Yuki , Xiaojiang Gao , Colm O'hUigin , Malini Raghavan , Steven Wolinsky , Jay H Bream , Priya Duggal , Jeremy Martinson , Nelson L Michael , Gregory D Kirk , Susan P Buchbinder , David Haas , James J Goedert , Steven G Deeks , Jacques Fellay , Bruce Walker , Philip Goulder , Peter Cresswell , Tim Elliott , Alessandro Sette , Jonathan Carlson , Mary Carrington

Virosaurus A Reference to Explore and Capture Virus Genetic Diversity.

Viruses

Avec: Anne Gleizes , Florian Laubscher , Nicolas Guex , Christian Iseli , Thomas Junier , Samuel Cordey , Jacques Fellay , Ioannis Xenarios , Laurent Kaiser , Philippe Le Mercier

Heritability of the HIV-1 reservoir size and decay under long-term suppressive ART.

Nature communications

Avec: Chenjie Wan , Nadine Bachmann , Venelin Mitov , François Blanquart , Susana Posada Céspedes , Teja Turk , Kathrin Neumann , Niko Beerenwinkel , Jasmina Bogojeska , Jacques Fellay , Volker Roth , Jürg Böni , Matthieu Perreau , Thomas Klimkait , Sabine Yerly , Manuel Battegay , Laura Walti , Alexandra Calmy , Pietro Vernazza , Enos Bernasconi , Matthias Cavassini , Karin J Metzner , Huldrych F Günthard , Roger D Kouyos , Auteur inconnu

Rapid Progression of Kidney Dysfunction in People Living With HIV: Use of Polygenic and Data Collection on Adverse Events of Anti-HIV Drugs (D:A:D) Risk Scores.

The Journal of infectious diseases

Avec: Léna G Dietrich , Christian W Thorball , Lene Ryom , Felix Burkhalter , Barbara Hasse , Maria Christine Thurnheer , Maja Weisser , Patrick Schmid , Enos Bernasconi , Kathrine E A Darling , Hélène Buvelot , Jacques Fellay , Bruno Ledergerber , Philip E Tarr , Auteur inconnu

Increased CHIP Prevalence Amongst People Living with HIV.

medRxiv : the preprint server for health sciences

Avec: Alexander G Bick , Konstantin Popadin , Christian W Thorball , Md Mesbah Uddin , Markella Zanni , Bing Yu , Matthias Cavassini , Andri Rauch , Philip Tarr , Patrick Schmid , Enos Bernasconi , Huldrych F Günthard , Peter Libby , Eric Boerwinkle , Paul J McLaren , Christie M Ballantyne , Steven Grinspoon , Pradeep Natarajan , Jacques Fellay

Systematic screening of viral and human genetic variation identifies antiretroviral resistance and immune escape link.

eLife

Avec: Huyen Nguyen , Christian Wandell Thorball , Jacques Fellay , Jürg Böni , Sabine Yerly , Matthieu Perreau , Hans H Hirsch , Katharina Kusejko , Maria Christine Thurnheer , Manuel Battegay , Matthias Cavassini , Christian R Kahlert , Enos Bernasconi , Huldrych F Günthard , Roger D Kouyos , Auteur inconnu

Identifying and Characterizing Trans Women in the Swiss HIV Cohort Study as an Epidemiologically Distinct Risk Group.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Avec: Huyen Nguyen , Benjamin Hampel , David Garcia Nuñez , Manuel Battegay , Anna Hachfeld , Enos Bernasconi , Alexandra Calmy , Matthias Cavassini , Pietro Vernazza , Jacques Fellay , Hannes Rudolph , Michael Huber , Karoline Leuzinger , Matthieu Perreau , Alexandra Scherrer , Alban Nicolas Ramette , Sabine Yerly , Huldrych F Günthard , Roger D Kouyos , Katharina Kusejko , Auteur inconnu

Réseau de co-auteurs

None None 96 collaborations

Jacques Fellay 88 collaborations

Christian W Thorball 27 collaborations

Enos Bernasconi 23 collaborations

Huldrych F Günthard 23 collaborations

Matthias Cavassini 18 collaborations

Roger D Kouyos 16 collaborations

Paul J McLaren 12 collaborations

Philip E Tarr 11 collaborations

Bruno Ledergerber 10 collaborations

Andri Rauch 10 collaborations

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Flavia Hodel 8 collaborations

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