questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Métalloprotéines
Protéines de liaison au fer
Protéines à fer non hème
Lipoxygénases
Arachidonate lipoxygenases
Arachidonate 5-lipoxygenase
Arachidonate 5-lipoxygenase : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Lipoxygenases
Leucotriènes
Imagerie par résonance magnétique
Inflammation
Tests génétiques
Mutations
Symptômes
5
Asthme
Réactions allergiques
Crise d'asthme
Oppression thoracique
Prévention
5
Prévention de l'asthme
Allergènes
Régime alimentaire
Inflammation
Gestion du stress
Méditation
Exercice physique
Fonction pulmonaire
Traitements
5
Inhibiteurs de la lipoxygénase
Asthme
Anti-inflammatoires
Médiateurs
Acides gras oméga-3
Antioxydants
Corticostéroïdes
Réponse immunitaire
Bronchodilatateurs
Voies respiratoires
Complications
5
Infections respiratoires
Hospitalisations
Inflammation chronique
Maladies cardiovasculaires
Asthme
Dommages pulmonaires
Qualité de vie
Activités physiques
Facteurs de risque
5
Antécédents familiaux
Pollution
Tabagisme
Complications respiratoires
Infections respiratoires
Crises d'asthme
Exposition professionnelle
Irritants
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"@type": "Question",
"name": "Comment diagnostiquer une dysfonction de l'enzyme ?",
"position": 1,
"acceptedAnswer": {
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"text": "Des tests sanguins peuvent mesurer les niveaux de leucotriènes et d'autres biomarqueurs."
}
},
{
"@type": "Question",
"name": "Quels examens sont utilisés pour évaluer l'inflammation ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'échographie, l'IRM et les tests de laboratoire peuvent aider à évaluer l'inflammation."
}
},
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"@type": "Question",
"name": "Y a-t-il des tests génétiques pour l'arachidonate 5-lipoxygenase ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques peuvent identifier des mutations affectant l'enzyme, mais ils sont rares."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent un problème avec cette enzyme ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme l'asthme, les allergies ou des maladies inflammatoires peuvent indiquer un problème."
}
},
{
"@type": "Question",
"name": "Comment évaluer l'activité de l'enzyme dans le corps ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests biochimiques mesurent l'activité de l'enzyme dans des échantillons de tissus ou de sang."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une surproduction de leucotriènes ?",
"position": 6,
"acceptedAnswer": {
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"text": "Les symptômes incluent des crises d'asthme, des réactions allergiques et des inflammations chroniques."
}
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{
"@type": "Question",
"name": "Comment l'inflammation se manifeste-t-elle ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'inflammation peut se manifester par des rougeurs, des douleurs, un gonflement et une chaleur locale."
}
},
{
"@type": "Question",
"name": "Y a-t-il des signes d'allergies liés à cette enzyme ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des démangeaisons, des éruptions cutanées et des difficultés respiratoires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont associés à l'asthme ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent la toux, la respiration sifflante, l'essoufflement et la pression thoracique."
}
},
{
"@type": "Question",
"name": "Comment reconnaître une crise d'asthme ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une crise d'asthme se manifeste par une respiration difficile, une toux persistante et une oppression thoracique."
}
},
{
"@type": "Question",
"name": "Comment prévenir les crises d'asthme ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les allergènes, utiliser des médicaments préventifs et suivre un plan d'action personnalisé."
}
},
{
"@type": "Question",
"name": "Y a-t-il des mesures diététiques à prendre ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en fruits, légumes et oméga-3 peut aider à réduire l'inflammation."
}
},
{
"@type": "Question",
"name": "Comment gérer le stress pour prévenir l'inflammation ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques de gestion du stress comme la méditation et le yoga peuvent réduire l'inflammation."
}
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{
"@type": "Question",
"name": "Quels exercices sont bénéfiques pour les asthmatiques ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des exercices modérés comme la marche ou la natation peuvent améliorer la fonction pulmonaire."
}
},
{
"@type": "Question",
"name": "Comment éviter les irritants environnementaux ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Évitez la fumée, la pollution et les produits chimiques irritants pour protéger vos voies respiratoires."
}
},
{
"@type": "Question",
"name": "Quels médicaments ciblent l'arachidonate 5-lipoxygenase ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les inhibiteurs de la lipoxygénase, comme le zileuton, sont utilisés pour traiter l'asthme."
}
},
{
"@type": "Question",
"name": "Comment les anti-inflammatoires aident-ils ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils réduisent l'inflammation en inhibant la production de leucotriènes et d'autres médiateurs."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements naturels disponibles ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des acides gras oméga-3 et des antioxydants peuvent aider à moduler l'inflammation."
}
},
{
"@type": "Question",
"name": "Quels sont les effets des corticostéroïdes ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les corticostéroïdes réduisent l'inflammation et la réponse immunitaire, soulageant les symptômes."
}
},
{
"@type": "Question",
"name": "Comment les bronchodilatateurs agissent-ils ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils dilatent les voies respiratoires, facilitant la respiration et réduisant les symptômes d'asthme."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec l'asthme ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des infections respiratoires, des crises d'asthme sévères et des hospitalisations."
}
},
{
"@type": "Question",
"name": "Comment l'inflammation chronique affecte-t-elle la santé ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'inflammation chronique peut entraîner des maladies cardiovasculaires et des troubles métaboliques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de développement d'allergies ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une exposition prolongée à des allergènes peut augmenter le risque de développer des allergies."
}
},
{
"@type": "Question",
"name": "Quels sont les effets à long terme de l'asthme non contrôlé ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'asthme non contrôlé peut entraîner des dommages pulmonaires permanents et une qualité de vie réduite."
}
},
{
"@type": "Question",
"name": "Comment l'asthme peut-il affecter la vie quotidienne ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'asthme peut limiter les activités physiques, affecter le sommeil et entraîner des absences scolaires ou professionnelles."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour l'asthme ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux, l'exposition à des allergènes et la pollution sont des facteurs de risque."
}
},
{
"@type": "Question",
"name": "Comment le tabagisme influence-t-il l'asthme ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme aggrave les symptômes d'asthme et augmente le risque de complications respiratoires."
}
},
{
"@type": "Question",
"name": "Y a-t-il un lien entre l'obésité et l'asthme ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'obésité est un facteur de risque qui peut aggraver les symptômes et la gravité de l'asthme."
}
},
{
"@type": "Question",
"name": "Quels rôles jouent les infections respiratoires ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les infections respiratoires peuvent déclencher des crises d'asthme et aggraver l'inflammation."
}
},
{
"@type": "Question",
"name": "Comment l'exposition professionnelle affecte-t-elle l'asthme ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exposition à des irritants ou allergènes au travail peut augmenter le risque d'asthme professionnel."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 06/04/2025
Contenu vérifié selon les dernières recommandations médicales
7 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt/Main, Germany.
6 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt/Main, Germany.
6 publications dans cette catégorie
Affiliations :
Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University, Jena, Germany.
6 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, D-10117 Berlin, Germany.
5 publications dans cette catégorie
Affiliations :
Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University, Jena, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, D-10117 Berlin, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, 60438 Frankfurt, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Department of Integrative Bioscience and Biotechnology, Konkuk University, Seoul, 05029, Republic of Korea.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Department of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, Republic of Korea. deokkun@konkuk.ac.kr.
Department of Integrative Bioscience and Biotechnology, Konkuk University, Seoul, 05029, Republic of Korea. deokkun@konkuk.ac.kr.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan. Electronic address: toshiko@fhw.oka-pu.ac.jp.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, 100730 People's Republic of China.
Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, 100005 People's Republic of China.
Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, 100730 People's Republic of China.
Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, 100005 People's Republic of China.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Division of Clinical Pharmacology, Department of Pharmacology, and Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical School, Nashville, Tennessee 37232, United States.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Institute for Clinical Pharmacology, Goethe University, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University, Max-von-Laue-Straße 9, 60438 Frankfurt, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
2 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
2 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
Genetic counseling is a relatively young profession that has advanced rapidly over the last 50 years. The term "genetic counseling" was first coined by Sheldon Reed in 1947 to describe the advice he w...
Prenatal genetic testing can be divided into two categories: screening and diagnostic. This article will focus on reviewing prenatal genetic screening tests....
Cell-free DNA (cfDNA) is a new prenatal genetic screening test with a high degree of accuracy for identifying certain genetic conditions like trisomy 21, 18, and 13. However, cfDNA has also been appli...
Prenatal genetic screening evaluates at risk pregnancies - including both carrier screening, which can be done at any point in a person's life, and aneuploidy screening, which is done during pregnancy...
Prenatal genetic testing can be divided into two categories: screening and diagnosis. Prenatal genetic screening tests are used to assess carrier status or as a fetal risk assessment for a particular ...
Next generation sequencing (NGS) has revolutionized prenatal genetic diagnostic testing. NGS methods are becoming more advanced and accurate as more genetic information is being linked to genetic cond...
Prenatal genetic diagnostic testing involves clinicians invasively obtaining tissue via amniocentesis or chorionic villus sampling to identify if a fetus has a genetic condition. This testing has trad...
Elective genetic testing (EGT) to identify disease risk in individuals who may or may not meet clinical criteria for testing is increasingly being offered in clinical practice. However, little is know...
Genetic testing for persons with Parkinson's disease is becoming increasingly common. Significant gains have been made regarding genetic testing methods, and testing is becoming more readily available...
There are thousands of different clinical genetic tests currently available. Genetic testing and its applications continue to change rapidly for multiple reasons. These reasons include technological a...
This article considers a number of key issues and axes related to the current and future state of clinical genetic testing, including targeted versus broad testing, simple/Mendelian versus polygenic a...
Genetic testing is expanding and evolving, including into new clinical applications. Developments in the field of genetics will likely result in genetic testing becoming increasingly in the purview of...
Implementation of genetic testing in healthcare increases, but access to, and number of, genetics providers remain scarce. This study analyzed the impact of genetic counselor (GC) involvement on frequ...
To evaluate the feasibility and impact of offering genetic testing and counseling to patients with Parkinson's disease (PD), with the potential to enroll in gene-targeted clinical trials and improve c...
A multicenter, exploratory pilot study at 7 academic hospital sites in the United States tracked enrollment and randomized participants to receive results and genetic counseling at local sites or by g...
From September 5, 2019 to January 4, 2021, 620 participants were enrolled and 387 completed outcome surveys. There were no significant differences in outcomes between local and remote sites, with both...
Local clinicians, as well as genetic counselors, with educational support as needed, can effectively return genetic results for PD as we observed favorable outcome measures in both groups. Increasing ...
Clinical guidelines recommend genetic testing when evaluating congenital and late-onset sensorineural hearing loss (SNHL). Genetic diagnoses can provide parents additional information regarding antici...
We included children ages 0-18 years with SNHL who were hearing aid or cochlear implant candidates but non-users and underwent hearing-loss gene panel testing prior to initiating intervention. Univari...
Of the 385 children with SNHL who underwent hearing loss gene panel testing, 111 were included. Median age was 7.5 years. 56% were underrepresented minorities, 71% were non-White, and 71% were publicl...
Up to half of children with SNHL are suspected to have an underlying genetic etiology. Children diagnosed with a genetic diagnosis are significantly more likely to subsequently utilize hearing aids or...
4 Laryngoscope, 133:1982-1986, 2023....
Leukodystrophies are monogenic disorders primarily affecting the white matter. We aimed to evaluate the utility of genetic testing and time-to-diagnosis in a retrospective cohort of children with susp...
Medical records of patients who attended the leukodystrophy clinic at the Dana-Dwek Children's Hospital between June 2019 and December 2021 were retrieved. Clinical, molecular, and neuroimaging data w...
Sixty-seven patients (Female/Male ratio 35/32) were included. Median age at symptom onset was 9 months (interquartile range (IQR) 3-18 months), and median length of follow-up was 4.75 years (IQR 3-8.5...
NGS carries the highest diagnostic yield in children with suspected leukodystrophy. Access to advanced sequencing technologies accelerates speed to diagnosis, which is increasingly crucial as targeted...