questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Métalloprotéines
Protéines de liaison au fer
Protéines à fer non hème
Lipoxygénases
Arachidonate lipoxygenases
Arachidonate 5-lipoxygenase
Arachidonate 5-lipoxygenase : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Lipoxygenases
Leucotriènes
Imagerie par résonance magnétique
Inflammation
Tests génétiques
Mutations
Symptômes
5
Asthme
Réactions allergiques
Crise d'asthme
Oppression thoracique
Prévention
5
Prévention de l'asthme
Allergènes
Régime alimentaire
Inflammation
Gestion du stress
Méditation
Exercice physique
Fonction pulmonaire
Traitements
5
Inhibiteurs de la lipoxygénase
Asthme
Anti-inflammatoires
Médiateurs
Acides gras oméga-3
Antioxydants
Corticostéroïdes
Réponse immunitaire
Bronchodilatateurs
Voies respiratoires
Complications
5
Infections respiratoires
Hospitalisations
Inflammation chronique
Maladies cardiovasculaires
Asthme
Dommages pulmonaires
Qualité de vie
Activités physiques
Facteurs de risque
5
Antécédents familiaux
Pollution
Tabagisme
Complications respiratoires
Infections respiratoires
Crises d'asthme
Exposition professionnelle
Irritants
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"@type": "Question",
"name": "Comment diagnostiquer une dysfonction de l'enzyme ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests sanguins peuvent mesurer les niveaux de leucotriènes et d'autres biomarqueurs."
}
},
{
"@type": "Question",
"name": "Quels examens sont utilisés pour évaluer l'inflammation ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'échographie, l'IRM et les tests de laboratoire peuvent aider à évaluer l'inflammation."
}
},
{
"@type": "Question",
"name": "Y a-t-il des tests génétiques pour l'arachidonate 5-lipoxygenase ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests génétiques peuvent identifier des mutations affectant l'enzyme, mais ils sont rares."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent un problème avec cette enzyme ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme l'asthme, les allergies ou des maladies inflammatoires peuvent indiquer un problème."
}
},
{
"@type": "Question",
"name": "Comment évaluer l'activité de l'enzyme dans le corps ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests biochimiques mesurent l'activité de l'enzyme dans des échantillons de tissus ou de sang."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une surproduction de leucotriènes ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent des crises d'asthme, des réactions allergiques et des inflammations chroniques."
}
},
{
"@type": "Question",
"name": "Comment l'inflammation se manifeste-t-elle ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'inflammation peut se manifester par des rougeurs, des douleurs, un gonflement et une chaleur locale."
}
},
{
"@type": "Question",
"name": "Y a-t-il des signes d'allergies liés à cette enzyme ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des démangeaisons, des éruptions cutanées et des difficultés respiratoires peuvent survenir."
}
},
{
"@type": "Question",
"name": "Quels symptômes sont associés à l'asthme ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes incluent la toux, la respiration sifflante, l'essoufflement et la pression thoracique."
}
},
{
"@type": "Question",
"name": "Comment reconnaître une crise d'asthme ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une crise d'asthme se manifeste par une respiration difficile, une toux persistante et une oppression thoracique."
}
},
{
"@type": "Question",
"name": "Comment prévenir les crises d'asthme ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter les allergènes, utiliser des médicaments préventifs et suivre un plan d'action personnalisé."
}
},
{
"@type": "Question",
"name": "Y a-t-il des mesures diététiques à prendre ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en fruits, légumes et oméga-3 peut aider à réduire l'inflammation."
}
},
{
"@type": "Question",
"name": "Comment gérer le stress pour prévenir l'inflammation ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques de gestion du stress comme la méditation et le yoga peuvent réduire l'inflammation."
}
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{
"@type": "Question",
"name": "Quels exercices sont bénéfiques pour les asthmatiques ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des exercices modérés comme la marche ou la natation peuvent améliorer la fonction pulmonaire."
}
},
{
"@type": "Question",
"name": "Comment éviter les irritants environnementaux ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Évitez la fumée, la pollution et les produits chimiques irritants pour protéger vos voies respiratoires."
}
},
{
"@type": "Question",
"name": "Quels médicaments ciblent l'arachidonate 5-lipoxygenase ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les inhibiteurs de la lipoxygénase, comme le zileuton, sont utilisés pour traiter l'asthme."
}
},
{
"@type": "Question",
"name": "Comment les anti-inflammatoires aident-ils ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils réduisent l'inflammation en inhibant la production de leucotriènes et d'autres médiateurs."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements naturels disponibles ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des acides gras oméga-3 et des antioxydants peuvent aider à moduler l'inflammation."
}
},
{
"@type": "Question",
"name": "Quels sont les effets des corticostéroïdes ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les corticostéroïdes réduisent l'inflammation et la réponse immunitaire, soulageant les symptômes."
}
},
{
"@type": "Question",
"name": "Comment les bronchodilatateurs agissent-ils ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils dilatent les voies respiratoires, facilitant la respiration et réduisant les symptômes d'asthme."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec l'asthme ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des infections respiratoires, des crises d'asthme sévères et des hospitalisations."
}
},
{
"@type": "Question",
"name": "Comment l'inflammation chronique affecte-t-elle la santé ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'inflammation chronique peut entraîner des maladies cardiovasculaires et des troubles métaboliques."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques de développement d'allergies ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une exposition prolongée à des allergènes peut augmenter le risque de développer des allergies."
}
},
{
"@type": "Question",
"name": "Quels sont les effets à long terme de l'asthme non contrôlé ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'asthme non contrôlé peut entraîner des dommages pulmonaires permanents et une qualité de vie réduite."
}
},
{
"@type": "Question",
"name": "Comment l'asthme peut-il affecter la vie quotidienne ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'asthme peut limiter les activités physiques, affecter le sommeil et entraîner des absences scolaires ou professionnelles."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour l'asthme ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux, l'exposition à des allergènes et la pollution sont des facteurs de risque."
}
},
{
"@type": "Question",
"name": "Comment le tabagisme influence-t-il l'asthme ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme aggrave les symptômes d'asthme et augmente le risque de complications respiratoires."
}
},
{
"@type": "Question",
"name": "Y a-t-il un lien entre l'obésité et l'asthme ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'obésité est un facteur de risque qui peut aggraver les symptômes et la gravité de l'asthme."
}
},
{
"@type": "Question",
"name": "Quels rôles jouent les infections respiratoires ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les infections respiratoires peuvent déclencher des crises d'asthme et aggraver l'inflammation."
}
},
{
"@type": "Question",
"name": "Comment l'exposition professionnelle affecte-t-elle l'asthme ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "L'exposition à des irritants ou allergènes au travail peut augmenter le risque d'asthme professionnel."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 06/04/2025
Contenu vérifié selon les dernières recommandations médicales
7 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt/Main, Germany.
6 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University, Frankfurt/Main, Germany.
6 publications dans cette catégorie
Affiliations :
Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University, Jena, Germany.
6 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, D-10117 Berlin, Germany.
5 publications dans cette catégorie
Affiliations :
Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University, Jena, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, D-10117 Berlin, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, 60438 Frankfurt, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Department of Integrative Bioscience and Biotechnology, Konkuk University, Seoul, 05029, Republic of Korea.
Publications dans "Arachidonate 5-lipoxygenase" :
4 publications dans cette catégorie
Affiliations :
Department of Bioscience and Biotechnology, Konkuk University, Seoul, 05029, Republic of Korea. deokkun@konkuk.ac.kr.
Department of Integrative Bioscience and Biotechnology, Konkuk University, Seoul, 05029, Republic of Korea. deokkun@konkuk.ac.kr.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan. Electronic address: toshiko@fhw.oka-pu.ac.jp.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Otolaryngology, Head and Neck Surgery, Beijing TongRen Hospital, Capital Medical University, Beijing, 100730 People's Republic of China.
Beijing Key Laboratory of Nasal Diseases, Beijing Institute of Otolaryngology, Beijing, 100005 People's Republic of China.
Department of Allergy, Beijing TongRen Hospital, Capital Medical University, Beijing, 100730 People's Republic of China.
Research Unit of Diagnosis and Treatment of Chronic Nasal Diseases, Chinese Academy of Medical Sciences, Beijing, 100005 People's Republic of China.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Division of Clinical Pharmacology, Department of Pharmacology, and Vanderbilt Institute of Chemical Biology, Vanderbilt University Medical School, Nashville, Tennessee 37232, United States.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Institute for Clinical Pharmacology, Goethe University, Medical Faculty, Theodor-Stern-Kai 7, 60590 Frankfurt, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Chemistry, Goethe University, Max-von-Laue-Straße 9, 60438 Frankfurt, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
3 publications dans cette catégorie
Affiliations :
Department of Biochemistry, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.
Publications dans "Arachidonate 5-lipoxygenase" :
2 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
2 publications dans cette catégorie
Affiliations :
Department of Nutritional Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Publications dans "Arachidonate 5-lipoxygenase" :
Helicobacter pylori (H. pylori) and cardiovascular (CV) disease share common symptoms and underlie many general medical complaints. Preliminary studies suggest an association between H. pylori positiv...
We included 3284 asymptomatic participants of a colorectal cancer screening cohort who were offered and underwent upper gastrointestinal endoscopy. We calculated the 10-year risk for a CV event using ...
In total, 2659 patients were H. pylori negative and 625 H. pylori positive. Helicobacter pylori positivity was associated with SCORE2 and remained so (r = .33; 95% CI 0.09-0.57; p = .006) after adjust...
In our study, H. pylori positivity and CV risk were independently associated. This did not translate into a dissimilar CV mortality between H. pylori positive and H. pylori negative patients. However,...
At present, eradication regimens for non-Helicobacter pylori Helicobacter (NHPH) have not been established yet. We investigated effectiveness of the standard triple-drug combination therapy for Helico...
Subjects were the patients who were diagnosed with NHPH-infected gastritis based on microscopic findings, helical-shaped organisms obviously larger than Helicobacter pylori, in the gastric mucosal spe...
PCR analysis detected NHPH in 38 patients: 36 as Helicobacter suis and two as Helicobacter heilmannii/Helicobacter ailurogastricus. Fourteen Helicobacter suis-infected and one Helicobacter heilmannii/...
In NHPH eradication, the triple-drug combination therapy was considered to be effective to some extent and to become the first-line therapy. While, although less successful, PPI monotherapy appeared t...
This study was approved by the Research Ethics Committee of Kenwakai Hospital (No. 2,017,024)....
The gut microbiota has recently emerged as a unique mechanism of immunotherapeutic resistance or response within certain cancer patients. Certain adherent bacterial species that reside along the epith...
Drug resistance in Helicobacter pylori severely affects the efficacy of eradication therapy, and a number of studies have been conducted on this issue. The aim of this study was to assess the progress...
Publications related to H. pylori resistance from 2002 to 2022 were retrieved from the Web of Science database. Relevant information including titles, authors, countries, and keywords was extracted, a...
From 2002 to 2022 (as of 09/24/2022), the field of H. pylori-resistance research produced a total of 2677 publications with a total of 75217 citations, with an overall upward trend in the annual numbe...
H. pylori-resistance research has become a popular research field, and although there are significant contributions from Europe, the United States, and East Asia, there are significant imbalances betw...
Recently, the relationship between Helicobacter cinaedi (H. cinaedi) infection and several diseases, including cardiovascular and central nervous system disorders, bone and soft tissue disorders, and ...
Helicobacter pylori bacteremia is rare and difficult to make a definite diagnosis....
This is a 40-year-old woman represented as fever and unconsciousness accompanied by tics. She was diagnosed as Helicobacter pylori bacteremia and received emergency endotracheal intubation and antibio...
Helicobacter pylori bacteremia is rare and hard to identify. Varied clinical manifestations leading to more difficult to make a definite diagnosis....
Helicobacter cinaedi is known to cause invasive infections in immunocompromised adults. Here we report the first case of H. cinaedi bacteremia in a child with nephrotic syndrome. The patient presented...
Autosomal recessive agammaglobulinemia is a severe primary antibody deficiency disorder typically presenting in infancy. We present a rare case of an 8-year-old boy with AR agammaglobulinemia due to a...
Helicobacter bilis, an enterohepatic Helicobacter species, represents a carcinogenic risk factor for cholangiocytes owing to the prevalence of infections in patients with biliary tract cancer, cholecy...
Helicobacter bilis and MMNK-1 cells were cocultured for 24 h and inflammatory cytokine secretion was evaluated. Furthermore, MMNK-1 cell proliferation, intracellular reactive oxidant species (ROS) pro...
Interleukin (IL)-6 and IL-8 secretion were significantly increased in MMNK-1 cocultures with H. bilis (IL-6, 24.3 ± 12.2 vs. 271.1 ± 286.4 pg/ml; IL-8, 167.6 ± 78.7 vs. 1085.1 ± 1047.1 pg/ml, p < .05)...
Helicobacter bilis infection induced ROS production in and enhanced the proliferation of cholangiocytes....
Recently, numerous publications on Helicobacter pylori (H. pylori) have been published, but bibliometric analyses on this research field are scarce. To address this gap, we conducted a bibliometric an...
Publications on H. pylori from 2002 to 2021 were retrieved from the Web of Science Core Collection database (WoSCC). Trends in publications and citations were analyzed using Excel 2021. VOSviewer and ...
36,266 publications on H. pylori were retrieved from the WoSCC database. In general, we observed an increasing trend in the number of publications over the past 20 years. The United States was the mos...
The United States has been the most productive and influential country on H. pylori research, and H. pylori-related research remains an active research field. The relationship between H. pylori infect...