Christian Kuppe

Affiliations

Centre for Photonics and Photonic Materials , University of Bath , Bath BA2 7AY , United Kingdom.
Centre for Nanoscience and Nanotechnology , University of Bath , Bath BA2 7AY , United Kingdom.
Department of Physics , University of Bath , Claverton Down, Bath BA2 7AY , United Kingdom.

Publications (51)

Disruption of CUL3-mediated ubiquitination causes proximal tubule injury and kidney fibrosis.

Scientific reports

Avec: Turgay Saritas , Catherina A Cuevas , Mohammed Z Ferdaus , Christoph Kuppe , Rafael Kramann , Marcus J Moeller , Jürgen Floege , Jeffrey D Singer , James A McCormick

Novel parietal epithelial cell subpopulations contribute to focal segmental glomerulosclerosis and glomerular tip lesions.

Kidney international

Avec: Christoph Kuppe , Katja Leuchtle , Anton Wagner , Nazanin Kabgani , Turgay Saritas , Victor G Puelles , Bart Smeets , Samy Hakroush , Johan van der Vlag , Peter Boor , Mario Schiffer , Hermann-Josef Gröne , Agnes Fogo , Jürgen Floege , Marcus Johannes Moeller

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ACS nano

Avec: Zichen Liu , Alexander William Allen Murphy , Christian Kuppe , David Charles Hooper , Ventsislav Kolev Valev , Adelina Ilie

Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen.

Nature communications

Avec: Zhijian Li , Christoph Kuppe , Susanne Ziegler , Mingbo Cheng , Nazanin Kabgani , Sylvia Menzel , Martin Zenke , Rafael Kramann , Ivan G Costa

Experimental and computational technologies to dissect the kidney at the single-cell level.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Avec: Christoph Kuppe , Javier Perales-Patón , Julio Saez-Rodriguez , Rafael Kramann

Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis.

Cell stem cell

Avec: Nils B Leimkühler , Hélène F E Gleitz , Li Ronghui , Inge A M Snoeren , Stijn N R Fuchs , James S Nagai , Bella Banjanin , King H Lam , Thomas Vogl , Christoph Kuppe , Ursula S A Stalmann , Guntram Büsche , Hans Kreipe , Ines Gütgemann , Philippe Krebs , Yara Banz , Peter Boor , Evelyn Wing-Yin Tai , Tim H Brümmendorf , Steffen Koschmieder , Martina Crysandt , Eric Bindels , Rafael Kramann , Ivan G Costa , Rebekka K Schneider

Exploring the genetic and functional diversity of Porphyromonas gingivalis long fimbriae.

Molecular oral microbiology

Avec: Hendrik Leonhard Meyer , Mohamed M H Abdelbary , Eva Miriam Buhl , Christoph Kuppe , Georg Conrads

Spatial multi-omic map of human myocardial infarction.

Nature

Avec: Christoph Kuppe , Ricardo O Ramirez Flores , Zhijian Li , Sikander Hayat , Rebecca T Levinson , Xian Liao , Monica T Hannani , Jovan Tanevski , Florian Wünnemann , James S Nagai , Maurice Halder , David Schumacher , Sylvia Menzel , Gideon Schäfer , Konrad Hoeft , Mingbo Cheng , Susanne Ziegler , Xiaoting Zhang , Fabian Peisker , Nadine Kaesler , Turgay Saritas , Yaoxian Xu , Astrid Kassner , Jan Gummert , Michiel Morshuis , Junedh Amrute , Rogier J A Veltrop , Peter Boor , Karin Klingel , Linda W Van Laake , Aryan Vink , Remco M Hoogenboezem , Eric M J Bindels , Leon Schurgers , Susanne Sattler , Denis Schapiro , Rebekka K Schneider , Kory Lavine , Hendrik Milting , Ivan G Costa , Julio Saez-Rodriguez , Rafael Kramann

Adult human kidney organoids originate from CD24

Nature genetics

Avec: Yaoxian Xu , Christoph Kuppe , Javier Perales-Patón , Sikander Hayat , Jennifer Kranz , Ali T Abdallah , James Nagai , Zhijian Li , Fabian Peisker , Turgay Saritas , Maurice Halder , Sylvia Menzel , Konrad Hoeft , Annegien Kenter , Hyojin Kim , Claudia R C van Roeyen , Michael Lehrke , Julia Moellmann , Thimoteus Speer , Eva M Buhl , Remco Hoogenboezem , Peter Boor , Jitske Jansen , Cordula Knopp , Ingo Kurth , Bart Smeets , Eric Bindels , Marlies E J Reinders , Carla Baan , Joost Gribnau , Ewout J Hoorn , Joachim Steffens , Tobias B Huber , Ivan Costa , Jürgen Floege , Rebekka K Schneider , Julio Saez-Rodriguez , Benjamin S Freedman , Rafael Kramann

A small-molecule TNIK inhibitor targets fibrosis in preclinical and clinical models.

Nature biotechnology

Avec: Feng Ren , Alex Aliper , Jian Chen , Heng Zhao , Sujata Rao , Christoph Kuppe , Ivan V Ozerov , Man Zhang , Klaus Witte , Chris Kruse , Vladimir Aladinskiy , Yan Ivanenkov , Daniil Polykovskiy , Yanyun Fu , Eugene Babin , Junwen Qiao , Xing Liang , Zhenzhen Mou , Hui Wang , Frank W Pun , Pedro Torres Ayuso , Alexander Veviorskiy , Dandan Song , Sang Liu , Bei Zhang , Vladimir Naumov , Xiaoqiang Ding , Andrey Kukharenko , Evgeny Izumchenko , Alex Zhavoronkov

mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans.

JCI insight

Avec: Victor G Puelles , James W van der Wolde , Nicola Wanner , Markus W Scheppach , Luise A Cullen-McEwen , Tillmann Bork , Maja T Lindenmeyer , Lukas Gernhold , Milagros N Wong , Fabian Braun , Clemens D Cohen , Michelle M Kett , Christoph Kuppe , Rafael Kramann , Turgay Saritas , Claudia R van Roeyen , Marcus J Moeller , Leon Tribolet , Richard Rebello , Yu By Sun , Jinhua Li , Gerhard Müller-Newen , Michael D Hughson , Wendy E Hoy , Fermin Person , Thorsten Wiech , Sharon D Ricardo , Peter G Kerr , Kate M Denton , Luc Furic , Tobias B Huber , David J Nikolic-Paterson , John F Bertram

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids.

Cell stem cell

Avec: Jitske Jansen , Katharina C Reimer , James S Nagai , Finny S Varghese , Gijs J Overheul , Marit de Beer , Rona Roverts , Deniz Daviran , Liline A S Fermin , Brigith Willemsen , Marcel Beukenboom , Sonja Djudjaj , Saskia von Stillfried , Larissa E van Eijk , Mirjam Mastik , Marian Bulthuis , Wilfred den Dunnen , Harry van Goor , Jan-Luuk Hillebrands , Sergio H Triana , Theodore Alexandrov , Marie-Cherelle Timm , Bartholomeus T van den Berge , Martijn van den Broek , Quincy Nlandu , Joelle Heijnert , Eric M J Bindels , Remco M Hoogenboezem , Fieke Mooren , Christoph Kuppe , Pascal Miesen , Katrien Grünberg , Ties Ijzermans , Eric J Steenbergen , Jan Czogalla , Michiel F Schreuder , Nico Sommerdijk , Anat Akiva , Peter Boor , Victor G Puelles , Jürgen Floege , Tobias B Huber , Auteur inconnu , Ronald P van Rij , Ivan G Costa , Rebekka K Schneider , Bart Smeets , Rafael Kramann

[Urosepsis-targeted diagnostics and effective therapy].

Urologie (Heidelberg, Germany)

Avec: Jennifer Kranz , Fabian Stangl , Christoph Kuppe , Florian Wagenlehner , Matthias Saar , Laila Schneidewind

New tools to study renal fibrogenesis.

Current opinion in nephrology and hypertension

Avec: Xian Liao , Emilia Scheidereit , Christoph Kuppe

Dissecting CD8+ T cell pathology of severe SARS-CoV-2 infection by single-cell immunoprofiling.

Frontiers in immunology

Avec: Felix Schreibing , Monica T Hannani , Hyojin Kim , James S Nagai , Fabio Ticconi , Eleanor Fewings , Tore Bleckwehl , Matthias Begemann , Natalia Torow , Christoph Kuppe , Ingo Kurth , Jennifer Kranz , Dario Frank , Teresa M Anslinger , Patrick Ziegler , Thomas Kraus , Jürgen Enczmann , Vera Balz , Frank Windhofer , Paul Balfanz , Christian Kurts , Gernot Marx , Nikolaus Marx , Michael Dreher , Rebekka K Schneider , Julio Saez-Rodriguez , Ivan Costa , Sikander Hayat , Rafael Kramann

[Artificial intelligence in urology-opportunities and possibilities].

Urologie (Heidelberg, Germany)

Avec: Radu Alexa , Jennifer Kranz , Christoph Kuppe , Sikander Hayat , Marco Hoffmann , Matthias Saar

Expansion-enhanced super-resolution radial fluctuations enable nanoscale molecular profiling of pathology specimens.

Nature nanotechnology

Avec: Dominik Kylies , Marina Zimmermann , Fabian Haas , Maria Schwerk , Malte Kuehl , Michael Brehler , Jan Czogalla , Lola C Hernandez , Leonie Konczalla , Yusuke Okabayashi , Julia Menzel , Ilka Edenhofer , Sam Mezher , Hande Aypek , Bernhard Dumoulin , Hui Wu , Smilla Hofmann , Oliver Kretz , Nicola Wanner , Nicola M Tomas , Susanne Krasemann , Markus Glatzel , Christoph Kuppe , Rafael Kramann , Bella Banjanin , Rebekka K Schneider , Christopher Urbschat , Petra Arck , Nicola Gagliani , Marc van Zandvoort , Thorsten Wiech , Florian Grahammer , Pablo J Sáez , Milagros N Wong , Stefan Bonn , Tobias B Huber , Victor G Puelles

Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses.

Molecular systems biology

Avec: Aurelien Dugourd , Christoph Kuppe , Marco Sciacovelli , Enio Gjerga , Attila Gabor , Kristina B Emdal , Vitor Vieira , Dorte B Bekker-Jensen , Jennifer Kranz , Eric M J Bindels , Ana S H Costa , Abel Sousa , Pedro Beltrao , Miguel Rocha , Jesper V Olsen , Christian Frezza , Rafael Kramann , Julio Saez-Rodriguez

Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis.

Kidney international

Avec: Victor G Puelles , David Fleck , Lena Ortz , Stella Papadouri , Thiago Strieder , Alexander M C Böhner , James W van der Wolde , Michael Vogt , Turgay Saritas , Christoph Kuppe , Astrid Fuss , Sylvia Menzel , Barbara M Klinkhammer , Gerhard Müller-Newen , Felix Heymann , Leon Decker , Fabian Braun , Oliver Kretz , Tobias B Huber , Etsuo A Susaki , Hiroki R Ueda , Peter Boor , Jürgen Floege , Rafael Kramann , Christian Kurts , John F Bertram , Marc Spehr , David J Nikolic-Paterson , Marcus J Moeller

A Functional Landscape of CKD Entities From Public Transcriptomic Data.

Kidney international reports

Avec: Ferenc Tajti , Christoph Kuppe , Asier Antoranz , Mahmoud M Ibrahim , Hyojin Kim , Francesco Ceccarelli , Christian H Holland , Hannes Olauson , Jürgen Floege , Leonidas G Alexopoulos , Rafael Kramann , Julio Saez-Rodriguez

Only Hyperuricemia with Crystalluria, but not Asymptomatic Hyperuricemia, Drives Progression of Chronic Kidney Disease.

Journal of the American Society of Nephrology : JASN

Avec: Markus Sellmayr , Moritz Roman Hernandez Petzsche , Qiuyue Ma , Nils Krüger , Helen Liapis , Andreas Brink , Barbara Lenz , Maria Lucia Angelotti , Viviane Gnemmi , Christoph Kuppe , Hyojin Kim , Eric Moniqué Johannes Bindels , Ferenc Tajti , Julio Saez-Rodriguez , Maciej Lech , Rafael Kramann , Paola Romagnani , Hans-Joachim Anders , Stefanie Steiger

Simulating Crop Root Systems Using OpenSimRoot.

Methods in molecular biology (Clifton, N.J.)

Avec: Ernst D Schäfer , Markus R Owen , Johannes A Postma , Christian Kuppe , Christopher K Black , Jonathan P Lynch

Deep learning-based molecular morphometrics for kidney biopsies.

JCI insight

Avec: Marina Zimmermann , Martin Klaus , Milagros N Wong , Ann-Katrin Thebille , Lukas Gernhold , Christoph Kuppe , Maurice Halder , Jennifer Kranz , Nicola Wanner , Fabian Braun , Sonia Wulf , Thorsten Wiech , Ulf Panzer , Christian F Krebs , Elion Hoxha , Rafael Kramann , Tobias B Huber , Stefan Bonn , Victor G Puelles

Prevention of vascular calcification by the endogenous chromogranin A-derived mediator that inhibits osteogenic transdifferentiation.

Basic research in cardiology

Avec: Setareh Orth-Alampour , Nathalie Gayrard , Silvia Salem , Shruti Bhargava , Vera Jankowski , Bernard Jover , Cécile Notarnicola , Heidi Noels , Emiel P C van der Vorst , Christoph Kuppe , Michael Wolf , Claudia Goettsch , Wendy Theelen , Heike Bruck , Danilo Fliser , Joseph Loscalzo , Zhuojun Wu , Nikolaus Marx , Walter Zidek , Àngel Argilés , Joachim Jankowski

Dynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression.

Nature communications

Avec: Marco Sciacovelli , Aurelien Dugourd , Lorea Valcarcel Jimenez , Ming Yang , Efterpi Nikitopoulou , Ana S H Costa , Laura Tronci , Veronica Caraffini , Paulo Rodrigues , Christina Schmidt , Dylan Gerard Ryan , Timothy Young , Vincent R Zecchini , Sabrina H Rossi , Charlie Massie , Caroline Lohoff , Maria Masid , Vassily Hatzimanikatis , Christoph Kuppe , Alex Von Kriegsheim , Rafael Kramann , Vincent Gnanapragasam , Anne Y Warren , Grant D Stewart , Ayelet Erez , Sakari Vanharanta , Julio Saez-Rodriguez , Christian Frezza

Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol.

Cardiovascular research

Avec: Kim van Kuijk , Ian R McCracken , Renée J H A Tillie , Sebastiaan E J Asselberghs , Dlzar A Kheder , Stan Muitjens , Han Jin , Richard S Taylor , Ruud Wichers Schreur , Christoph Kuppe , Ross Dobie , Prakesh Ramachandran , Marion J Gijbels , Lieve Temmerman , Phoebe M Kirkwoord , Joris Luyten , Yanming Li , Heidi Noels , Pieter Goossens , John R Wilson-Kanamori , Leon J Schurgers , Ying H Shen , Barend M E Mees , Erik A L Biessen , Neil C Henderson , Rafael Kramann , Andrew H Baker , Judith C Sluimer

Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases.

Genome medicine

Avec: Paul Kiessling , Christoph Kuppe

Identification of platelet-derived growth factor C as a mediator of both renal fibrosis and hypertension.

Kidney international

Avec: Claudia R C van Roeyen , Ina V Martin , Ana Drescher , Katharina A Schuett , Daniela Hermert , Ute Raffetseder , Stephanie Otten , Eva M Buhl , Gerald S Braun , Christoph Kuppe , Elisa Liehn , Peter Boor , Ralf Weiskirchen , Ulf Eriksson , Oliver Gross , Frank Eitner , Jürgen Floege , Tammo Ostendorf

Heterogeneity and plasticity in healthy and atherosclerotic vasculature explored by single-cell sequencing.

Cardiovascular research

Avec: Kim van Kuijk , Christoph Kuppe , Christer Betsholtz , Michael Vanlandewijck , Rafael Kramann , Judith C Sluimer

Altered vitamin K biodistribution and metabolism in experimental and human chronic kidney disease.

Kidney international

Avec: Nadine Kaesler , Felix Schreibing , Thimoteus Speer , Sofia de la Puente-Secades , Nikolas Rapp , Christiane Drechsler , Nazanin Kabgani , Christoph Kuppe , Peter Boor , Vera Jankowski , Leon Schurgers , Rafael Kramann , Jürgen Floege

Mapping the cardiac vascular niche in heart failure.

Nature communications

Avec: Fabian Peisker , Maurice Halder , James Nagai , Susanne Ziegler , Nadine Kaesler , Konrad Hoeft , Ronghui Li , Eric M J Bindels , Christoph Kuppe , Julia Moellmann , Michael Lehrke , Christian Stoppe , Michael T Schaub , Rebekka K Schneider , Ivan Costa , Rafael Kramann

[Urothelial carcinoma of the upper urinary tract].

Urologie (Heidelberg, Germany)

Avec: Jennifer Kranz , Marco Hoffmann , Radu Alexa , Christoph Kuppe , Nadine Therese Gaisa , Matthias Saar

A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology.

Nature communications

Avec: Julian Petersen , Lukas Englmaier , Artem V Artemov , Irina Poverennaya , Ruba Mahmoud , Thibault Bouderlique , Marketa Tesarova , Ruslan Deviatiiarov , Anett Szilvásy-Szabó , Evgeny E Akkuratov , David Pajuelo Reguera , Hugo Zeberg , Marketa Kaucka , Maria Eleni Kastriti , Jan Krivanek , Tomasz Radaszkiewicz , Kristína Gömöryová , Sarah Knauth , David Potesil , Zbynek Zdrahal , Ranjani Sri Ganji , Anna Grabowski , Miriam E Buhl , Tomas Zikmund , Michaela Kavkova , Håkan Axelson , David Lindgren , Rafael Kramann , Christoph Kuppe , Ferenc Erdélyi , Zoltán Máté , Gábor Szabó , Till Koehne , Tibor Harkany , Kaj Fried , Jozef Kaiser , Peter Boor , Csaba Fekete , Jan Rozman , Petr Kasparek , Jan Prochazka , Radislav Sedlacek , Vitezslav Bryja , Oleg Gusev , Igor Adameyko

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Niklas Klümper , Ngoc Khanh Tran , Stefanie Zschäbitz , Oliver Hahn , Thomas Büttner , Florian Roghmann , Christian Bolenz , Friedemann Zengerling , Constantin Schwab , Dora Nagy , Marieta Toma , Glen Kristiansen , Hendrik Heers , Philipp Ivanyi , Günter Niegisch , Camilla Marisa Grunewald , Christopher Darr , Arian Farid , Katrin Schlack , Mahmoud Abbas , Can Aydogdu , Jozefina Casuscelli , Theresa Mokry , Michael Mayr , Dora Niedersüß-Beke , Steffen Rausch , Dimo Dietrich , Jonas Saal , Jörg Ellinger , Manuel Ritter , Abdullah Alajati , Christoph Kuppe , Joshua Meeks , Francisco E Vera Badillo , J Alberto Nakauma-González , Joost Boormans , Kerstin Junker , Arndt Hartmann , Viktor Grünwald , Michael Hölzel , Markus Eckstein

Harnessing Artificial Intelligence for Enhanced Renal Analysis: Automated Detection of Hydronephrosis and Precise Kidney Segmentation.

European urology open science

Avec: Radu Alexa , Jennifer Kranz , Rafael Kramann , Christoph Kuppe , Ritabrata Sanyal , Sikander Hayat , Luis Felipe Casas Murillo , Turkan Hajili , Marco Hoffmann , Matthias Saar

Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT).

Molecular systems biology

Avec: Mehdi Joodaki , Mina Shaigan , Victor Parra , Roman D Bülow , Christoph Kuppe , David L Hölscher , Mingbo Cheng , James S Nagai , Michaël Goedertier , Nassim Bouteldja , Vladimir Tesar , Jonathan Barratt , Ian Sd Roberts , Rosanna Coppo , Rafael Kramann , Peter Boor , Ivan G Costa

Increased levels of a mycophenolic acid metabolite in patients with kidney failure negatively affect cardiomyocyte health.

Frontiers in cardiovascular medicine

Avec: Eva Harlacher , Corinna Schulte , Sonja Vondenhoff , Philippe Schmitt-Kopplin , Philippe Diederich , Christian Hemmers , Julia Moellmann , Julia Wollenhaupt , Rogier Veltrop , Erik Biessen , Michael Lehrke , Björn Peters , Georg Schlieper , Christoph Kuppe , Jürgen Floege , Vera Jankowski , Nikolaus Marx , Joachim Jankowski , Heidi Noels

High serum sodium predicts immunotherapy response in metastatic renal cell and urothelial carcinoma.

European journal of cancer (Oxford, England : 1990)

Avec: Niklas Klümper , Alexander Cox , Markus Eckstein , Christoph Kuppe , Manuel Ritter , Peter Brossart , Julian Luetkens , Michael Hölzel , Johannes Stein , Jonas Saal

Generation of a conditional cellular senescence model using proximal tubule cells and fibroblasts from human kidneys.

Cell death discovery

Avec: Xiaohang Shao , Huaming Xu , Hyojin Kim , Sadaf Ljaz , Fabian Beier , Vera Jankowski , Michaela Lellig , Lucia Vankann , Jan Niklas Werner , Lu Chen , Susanne Ziegler , Christoph Kuppe , Martin Zenke , Rebekka K Schneider , Sikander Hayat , Turgay Saritas , Rafael Kramann

Targeting immune-fibroblast cell communication in heart failure.

Nature

Avec: Junedh M Amrute , Xin Luo , Vinay Penna , Steven Yang , Tracy Yamawaki , Sikander Hayat , Andrea Bredemeyer , In-Hyuk Jung , Farid F Kadyrov , Gyu Seong Heo , Rajiu Venkatesan , Sally Yu Shi , Alekhya Parvathaneni , Andrew L Koenig , Christoph Kuppe , Candice Baker , Hannah Luehmann , Cameran Jones , Benjamin Kopecky , Xue Zeng , Tore Bleckwehl , Pan Ma , Paul Lee , Yuriko Terada , Angela Fu , Milena Furtado , Daniel Kreisel , Atilla Kovacs , Nathan O Stitziel , Simon Jackson , Chi-Ming Li , Yongjian Liu , Nadia A Rosenthal , Rafael Kramann , Brandon Ason , Kory J Lavine

Second Harmonic Spectroscopy of Surface Lattice Resonances.

Nano letters

Avec: David C Hooper , Christian Kuppe , Danqing Wang , Weijia Wang , Jun Guan , Teri W Odom , Ventsislav K Valev

Modelling strategies for assessing and increasing the effectiveness of new phenotyping techniques in plant breeding.

Plant science : an international journal of experimental plant biology

Avec: Fred A van Eeuwijk , Daniela Bustos-Korts , Emilie J Millet , Martin P Boer , Willem Kruijer , Addie Thompson , Marcos Malosetti , Hiroyoshi Iwata , Roberto Quiroz , Christian Kuppe , Onno Muller , Konstantinos N Blazakis , Kang Yu , Francois Tardieu , Scott C Chapman

Decoding myofibroblast origins in human kidney fibrosis.

Nature

Avec: Christoph Kuppe , Mahmoud M Ibrahim , Jennifer Kranz , Xiaoting Zhang , Susanne Ziegler , Javier Perales-Patón , Jitske Jansen , Katharina C Reimer , James R Smith , Ross Dobie , John R Wilson-Kanamori , Maurice Halder , Yaoxian Xu , Nazanin Kabgani , Nadine Kaesler , Martin Klaus , Lukas Gernhold , Victor G Puelles , Tobias B Huber , Peter Boor , Sylvia Menzel , Remco M Hoogenboezem , Eric M J Bindels , Joachim Steffens , Jürgen Floege , Rebekka K Schneider , Julio Saez-Rodriguez , Neil C Henderson , Rafael Kramann

Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling.

Cardiovascular research

Avec: Kim van Kuijk , Jasper A F Demandt , Javier Perales-Patón , Thomas L Theelen , Christoph Kuppe , Elke Marsch , Jenny de Bruijn , Han Jin , Marion J Gijbels , Ljubica Matic , Barend M E Mees , Chris P M Reutelingsperger , Ulf Hedin , Erik A L Biessen , Peter Carmeliet , Andrew H Baker , Rafael K Kramann , Leon J Schurgers , Julio Saez-Rodriguez , Judith C Sluimer

Human pluripotent stem cell-derived kidney organoids for personalized congenital and idiopathic nephrotic syndrome modeling.

Development (Cambridge, England)

Avec: Jitske Jansen , Bartholomeus T van den Berge , Martijn van den Broek , Rutger J Maas , Deniz Daviran , Brigith Willemsen , Rona Roverts , Marit van der Kruit , Christoph Kuppe , Katharina C Reimer , Gianluca Di Giovanni , Fieke Mooren , Quincy Nlandu , Helmer Mudde , Roy Wetzels , Dirk den Braanker , Naomi Parr , James S Nagai , Vedran Drenic , Ivan G Costa , Eric Steenbergen , Tom Nijenhuis , Henry Dijkman , Nicole Endlich , Nicole C A J van de Kar , Rebekka K Schneider , Jack F M Wetzels , Anat Akiva , Johan van der Vlag , Rafael Kramann , Michiel F Schreuder , Bart Smeets

Impact of sucroferric oxyhydroxide on the oral and intestinal microbiome in hemodialysis patients.

Scientific reports

Avec: Mohamed M H Abdelbary , Christoph Kuppe , Sareh Said-Yekta Michael , Thilo Krüger , Jürgen Floege , Georg Conrads

Defining cardiac functional recovery in end-stage heart failure at single-cell resolution.

Nature cardiovascular research

Avec: Junedh M Amrute , Lulu Lai , Pan Ma , Andrew L Koenig , Kenji Kamimoto , Andrea Bredemeyer , Thirupura S Shankar , Christoph Kuppe , Farid F Kadyrov , Linda J Schulte , Dylan Stoutenburg , Benjamin J Kopecky , Sutip Navankasattusas , Joseph Visker , Samantha A Morris , Rafael Kramann , Florian Leuschner , Douglas L Mann , Stavros G Drakos , Kory J Lavine

Inhibition of the glucocorticoid receptor attenuates proteinuric kidney diseases in multiple species.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Avec: Eleni Stamellou , Shipra Agrawal , Florian Siegerist , Marc Buse , Christoph Kuppe , Tim Lange , Eva Miriam Buhl , Jessica Alam , Thiago Strieder , Peter Boor , Tammo Ostendorf , Hermann-Josef Gröne , Jürgen Floege , William E Smoyer , Nicole Endlich , Marcus J Moeller

scMEGA: single-cell multi-omic enhancer-based gene regulatory network inference.

Bioinformatics advances

Avec: Zhijian Li , James S Nagai , Christoph Kuppe , Rafael Kramann , Ivan G Costa

Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis.

Research square

Avec: Junedh M Amrute , Xin Luo , Vinay Penna , Andrea Bredemeyer , Tracy Yamawaki , Steven Yang , Farid Kadyrov , Gyu-Seong Heo , Sally Yu Shi , Paul Lee , Andrew L Koenig , Christoph Kuppe , Cameran Jones , Benjamin Kopecky , Sikander Hayat , Pan Ma , Yuriko Terada , Angela Fu , Milena Furtado , Daniel Kreisel , Nathan O Stitziel , Chi-Ming Li , Rafael Kramann , Yongjian Liu , Brandon Ason , Kory J Lavine

Platelet-instructed SPP1

Cell reports

Avec: Konrad Hoeft , Gideon J L Schaefer , Hyojin Kim , David Schumacher , Tore Bleckwehl , Qingqing Long , Barbara Mara Klinkhammer , Fabian Peisker , Lars Koch , James Nagai , Maurice Halder , Susanne Ziegler , Elisa Liehn , Christoph Kuppe , Jennifer Kranz , Sylvia Menzel , Ivan Costa , Adam Wahida , Peter Boor , Rebekka K Schneider , Sikander Hayat , Rafael Kramann

Réseau de co-auteurs

Christoph Kuppe 47 collaborations

Rafael Kramann 31 collaborations

Peter Boor 13 collaborations

Jürgen Floege 12 collaborations

Rebekka K Schneider 11 collaborations

Julio Saez-Rodriguez 10 collaborations

Jennifer Kranz 10 collaborations

Sikander Hayat 9 collaborations

Turgay Saritas 7 collaborations

Victor G Puelles 7 collaborations

Ivan G Costa 7 collaborations

James S Nagai 7 collaborations

Tobias B Huber 7 collaborations

Susanne Ziegler 6 collaborations

Sylvia Menzel 6 collaborations

Maurice Halder 6 collaborations

Hyojin Kim 6 collaborations

Eric M J Bindels 5 collaborations

Marcus J Moeller 4 collaborations

Nazanin Kabgani 4 collaborations

Bart Smeets 4 collaborations

Zhijian Li 4 collaborations

Javier Perales-Patón 4 collaborations

Konrad Hoeft 4 collaborations

Fabian Peisker 4 collaborations

Nadine Kaesler 4 collaborations

Jitske Jansen 4 collaborations

Ivan Costa 4 collaborations

Matthias Saar 4 collaborations

Vera Jankowski 4 collaborations

Mingbo Cheng 3 collaborations

Yaoxian Xu 3 collaborations

Remco M Hoogenboezem 3 collaborations

James Nagai 3 collaborations

Michael Lehrke 3 collaborations

Julia Moellmann 3 collaborations

Nicola Wanner 3 collaborations

Lukas Gernhold 3 collaborations

Milagros N Wong 3 collaborations

Fabian Braun 3 collaborations

Thorsten Wiech 3 collaborations

Katharina C Reimer 3 collaborations

Tore Bleckwehl 3 collaborations

Nikolaus Marx 3 collaborations

Radu Alexa 3 collaborations

Marco Hoffmann 3 collaborations

Heidi Noels 3 collaborations

Kim van Kuijk 3 collaborations

Judith C Sluimer 3 collaborations

Junedh M Amrute 3 collaborations

Andrea Bredemeyer 3 collaborations

Andrew L Koenig 3 collaborations

Pan Ma 3 collaborations

Kory J Lavine 3 collaborations

Johan van der Vlag 2 collaborations

Hermann-Josef Gröne 2 collaborations

Martin Zenke 2 collaborations

Bella Banjanin 2 collaborations

Eric Bindels 2 collaborations

Mohamed M H Abdelbary 2 collaborations

Eva Miriam Buhl 2 collaborations

Georg Conrads 2 collaborations

Xian Liao 2 collaborations

Monica T Hannani 2 collaborations

David Schumacher 2 collaborations

Xiaoting Zhang 2 collaborations

Leon Schurgers 2 collaborations

Claudia R C van Roeyen 2 collaborations

Thimoteus Speer 2 collaborations

Eva M Buhl 2 collaborations

Ingo Kurth 2 collaborations

Joachim Steffens 2 collaborations

James W van der Wolde 2 collaborations

Gerhard Müller-Newen 2 collaborations

David J Nikolic-Paterson 2 collaborations

John F Bertram 2 collaborations

Rona Roverts 2 collaborations

Deniz Daviran 2 collaborations

Brigith Willemsen 2 collaborations

Bartholomeus T van den Berge 2 collaborations

Martijn van den Broek 2 collaborations

Quincy Nlandu 2 collaborations

Fieke Mooren 2 collaborations

Jan Czogalla 2 collaborations

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