M Dichgans

Affiliations

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.
German Center for Neurodegenerative Diseases (DZNE, Munich), Munich, Germany.
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.

Publications (99)

Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes.

Neurology

Avec: Marios K Georgakis , Dipender Gill , Alastair J S Webb , Evangelos Evangelou , Paul Elliott , Cathie L M Sudlow , Abbas Dehghan , Rainer Malik , Ioanna Tzoulaki , Martin Dichgans

Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Avec: Nicolai Franzmeier , Nikolaos Koutsouleris , Tammie Benzinger , Alison Goate , Celeste M Karch , Anne M Fagan , Eric McDade , Marco Duering , Martin Dichgans , Johannes Levin , Brian A Gordon , Yen Ying Lim , Colin L Masters , Martin Rossor , Nick C Fox , Antoinette O'Connor , Jasmeer Chhatwal , Stephen Salloway , Adrian Danek , Jason Hassenstab , Peter R Schofield , John C Morris , Randall J Bateman , Auteur inconnu , Auteur inconnu , Michael Ewers

The effect of NOTCH3 pathogenic variant position on CADASIL disease severity: NOTCH3 EGFr 1-6 pathogenic variant are associated with a more severe phenotype and lower survival compared with EGFr 7-34 pathogenic variant.

Genetics in medicine : official journal of the American College of Medical Genetics

Avec: Julie W Rutten , Bastian J Van Eijsden , Marco Duering , Eric Jouvent , Christian Opherk , Leonardo Pantoni , Antonio Federico , Martin Dichgans , Hugh S Markus , Hugues Chabriat , Saskia A J Lesnik Oberstein

In vivo widefield calcium imaging of the mouse cortex for analysis of network connectivity in health and brain disease.

NeuroImage

Avec: Julia V Cramer , Benno Gesierich , Stefan Roth , Martin Dichgans , Marco Düring , Arthur Liesz

Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease.

Science translational medicine

Avec: Michael Ewers , Nicolai Franzmeier , Marc Suárez-Calvet , Estrella Morenas-Rodriguez , Miguel Angel Araque Caballero , Gernot Kleinberger , Laura Piccio , Carlos Cruchaga , Yuetiva Deming , Martin Dichgans , John Q Trojanowski , Leslie M Shaw , Michael W Weiner , Christian Haass , Auteur inconnu

Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects.

Circulation

Avec: Dipender Gill , Marios K Georgakis , Fotios Koskeridis , Lan Jiang , Qiping Feng , Wei-Qi Wei , Evropi Theodoratou , Paul Elliott , Joshua C Denny , Rainer Malik , Evangelos Evangelou , Abbas Dehghan , Martin Dichgans , Ioanna Tzoulaki

WMH and long-term outcomes in ischemic stroke: A systematic review and meta-analysis.

Neurology

Avec: Marios K Georgakis , Marco Duering , Joanna M Wardlaw , Martin Dichgans

The Meta VCI Map consortium for meta-analyses on strategic lesion locations for vascular cognitive impairment using lesion-symptom mapping: Design and multicenter pilot study.

Alzheimer's & dementia (Amsterdam, Netherlands)

Avec: Nick A Weaver , Lei Zhao , J Matthijs Biesbroek , Hugo J Kuijf , Hugo P Aben , Hee-Joon Bae , Miguel Á A Caballero , Francesca M Chappell , Christopher P L H Chen , Martin Dichgans , Marco Duering , Marios K Georgakis , Ruben S van der Giessen , Bibek Gyanwali , Olivia K L Hamilton , Saima Hilal , Elise M Vom Hofe , Paul L M de Kort , Peter J Koudstaal , Bonnie Y K Lam , Jae-Sung Lim , Stephen D J Makin , Vincent C T Mok , Lin Shi , Maria C Valdés Hernández , Narayanaswamy Venketasubramanian , Joanna M Wardlaw , Frank A Wollenweber , Adrian Wong , Xu Xin , Auteur inconnu , Geert Jan Biessels

Small vessel disease: mechanisms and clinical implications.

The Lancet. Neurology

Avec: Joanna M Wardlaw , Colin Smith , Martin Dichgans

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Neurology

Avec: Ganesh Chauhan , Hieab H H Adams , Claudia L Satizabal , Joshua C Bis , Alexander Teumer , Muralidharan Sargurupremraj , Edith Hofer , Stella Trompet , Saima Hilal , Albert Vernon Smith , Xueqiu Jian , Rainer Malik , Matthew Traylor , Sara L Pulit , Philippe Amouyel , Bernard Mazoyer , Yi-Cheng Zhu , Sara Kaffashian , Sabrina Schilling , Gary W Beecham , Thomas J Montine , Gerard D Schellenberg , Olafur Kjartansson , Vilmundur Guðnason , David S Knopman , Michael E Griswold , B Gwen Windham , Rebecca F Gottesman , Thomas H Mosley , Reinhold Schmidt , Yasaman Saba , Helena Schmidt , Fumihiko Takeuchi , Shuhei Yamaguchi , Toru Nabika , Norihiro Kato , Kumar B Rajan , Neelum T Aggarwal , Philip L De Jager , Denis A Evans , Bruce M Psaty , Jerome I Rotter , Kenneth Rice , Oscar L Lopez , Jiemin Liao , Christopher Chen , Ching-Yu Cheng , Tien Y Wong , Mohammad K Ikram , Sven J van der Lee , Najaf Amin , Vincent Chouraki , Anita L DeStefano , Hugo J Aparicio , Jose R Romero , Pauline Maillard , Charles DeCarli , Joanna M Wardlaw , Maria Del C Valdés Hernández , Michelle Luciano , David Liewald , Ian J Deary , John M Starr , Mark E Bastin , Susana Muñoz Maniega , P Eline Slagboom , Marian Beekman , Joris Deelen , Hae-Won Uh , Robin Lemmens , Henry Brodaty , Margaret J Wright , David Ames , Giorgio B Boncoraglio , Jemma C Hopewell , Ashley H Beecham , Susan H Blanton , Clinton B Wright , Ralph L Sacco , Wei Wen , Anbupalam Thalamuthu , Nicola J Armstrong , Elizabeth Chong , Peter R Schofield , John B Kwok , Jeroen van der Grond , David J Stott , Ian Ford , J Wouter Jukema , Meike W Vernooij , Albert Hofman , André G Uitterlinden , Aad van der Lugt , Katharina Wittfeld , Hans J Grabe , Norbert Hosten , Bettina von Sarnowski , Uwe Völker , Christopher Levi , Jordi Jimenez-Conde , Pankaj Sharma , Cathie L M Sudlow , Jonathan Rosand , Daniel Woo , John W Cole , James F Meschia , Agnieszka Slowik , Vincent Thijs , Arne Lindgren , Olle Melander , Raji P Grewal , Tatjana Rundek , Kathy Rexrode , Peter M Rothwell , Donna K Arnett , Christina Jern , Julie A Johnson , Oscar R Benavente , Sylvia Wasssertheil-Smoller , Jin-Moo Lee , Quenna Wong , Braxton D Mitchell , Stephen S Rich , Patrick F McArdle , Mirjam I Geerlings , Yolanda van der Graaf , Paul I W de Bakker , Folkert W Asselbergs , Velandai Srikanth , Russell Thomson , Rebekah McWhirter , Chris Moran , Michele Callisaya , Thanh Phan , Loes C A Rutten-Jacobs , Steve Bevan , Christophe Tzourio , Karen A Mather , Perminder S Sachdev , Cornelia M van Duijn , Bradford B Worrall , Martin Dichgans , Steven J Kittner , Hugh S Markus , Mohammad A Ikram , Myriam Fornage , Lenore J Launer , Sudha Seshadri , W T Longstreth , Stéphanie Debette , Auteur inconnu

Correction: The effect of NOTCH3 pathogenic variant position on CADASIL disease severity: NOTCH3 EGFr 1-6 pathogenic variant are associated with a more severe phenotype and lower survival compared with EGFr 7-34 pathogenic variant.

Genetics in medicine : official journal of the American College of Medical Genetics

European Stroke Organisation (ESO) standard operating procedure for the preparation and publishing of guidelines.

European stroke journal

Avec: T Steiner , M Dichgans , B Norrving , A H Aamodt , E Berge , H Christensen , B Fuentes , P Khatri , E Korompoki , J Martí-Fabregas , T Quinn , D Toni , M Zedde , S Sacco , G Turc

International stroke genetics consortium recommendations for studies of genetics of stroke outcome and recovery.

International journal of stroke : official journal of the International Stroke Society

Avec: Arne G Lindgren , Robynne G Braun , Jennifer Juhl Majersik , Philip Clatworthy , Shraddha Mainali , Colin P Derdeyn , Jane Maguire , Christina Jern , Jonathan Rosand , John W Cole , Jin-Moo Lee , Pooja Khatri , Paul Nyquist , Stéphanie Debette , Loo Keat Wei , Tatjana Rundek , Dana Leifer , Vincent Thijs , Robin Lemmens , Laura Heitsch , Kameshwar Prasad , Jordi Jimenez Conde , Martin Dichgans , Natalia S Rost , Steven C Cramer , Julie Bernhardt , Bradford B Worrall , Israel Fernandez-Cadenas , Auteur inconnu

Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies.

The Lancet. Neurology

Avec: Matthew Traylor , Elodie Persyn , Liisa Tomppo , Sofia Klasson , Vida Abedi , Mark K Bakker , Nuria Torres , Linxin Li , Steven Bell , Loes Rutten-Jacobs , Daniel J Tozer , Christoph J Griessenauer , Yanfei Zhang , Annie Pedersen , Pankaj Sharma , Jordi Jimenez-Conde , Tatjana Rundek , Raji P Grewal , Arne Lindgren , James F Meschia , Veikko Salomaa , Aki Havulinna , Christina Kourkoulis , Katherine Crawford , Sandro Marini , Braxton D Mitchell , Steven J Kittner , Jonathan Rosand , Martin Dichgans , Christina Jern , Daniel Strbian , Israel Fernandez-Cadenas , Ramin Zand , Ynte Ruigrok , Natalia Rost , Robin Lemmens , Peter M Rothwell , Christopher D Anderson , Joanna Wardlaw , Cathryn M Lewis , Hugh S Markus , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu

Patient-centered connectivity-based prediction of tau pathology spread in Alzheimer's disease.

Science advances

Avec: Nicolai Franzmeier , Anna Dewenter , Lukas Frontzkowski , Martin Dichgans , Anna Rubinski , Julia Neitzel , Ruben Smith , Olof Strandberg , Rik Ossenkoppele , Katharina Buerger , Marco Duering , Oskar Hansson , Michael Ewers

KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer's disease.

Nature communications

Avec: Julia Neitzel , Nicolai Franzmeier , Anna Rubinski , Martin Dichgans , Matthias Brendel , Auteur inconnu , Rainer Malik , Michael Ewers

Contribution of Common Genetic Variants to Risk of Early Onset Ischemic Stroke.

Neurology

Avec: Thomas Jaworek , Huichun Xu , Brady J Gaynor , John W Cole , Kristiina Rannikmae , Tara M Stanne , Liisa Tomppo , Vida Abedi , Philippe Amouyel , Nicole D Armstrong , John Attia , Steven Bell , Oscar R Benavente , Giorgio B Boncoraglio , Adam Butterworth , Auteur inconnu , Jara Carcel-Marquez , Zhengming Chen , Michael Chong , Carlos Cruchaga , Mary Cushman , John Danesh , Stephanie Debette , David J Duggan , Jon Peter Durda , Gunnar Engstrom , Chris Enzinger , Jessica D Faul , Natalie S Fecteau , Israel Fernandez-Cadenas , Christian Gieger , Anne-Katrin Giese , Raji P Grewal , Ulrike Grittner , Aki S Havulinna , Laura Heitsch , Marc C Hochberg , Elizabeth Holliday , Jie Hu , Andreea Ilinca , Auteur inconnu , Marguerite R Irvin , Rebecca D Jackson , Mina A Jacob , Raquel Rabionet Janssen , Jordi Jimenez-Conde , Julie A Johnson , Yoichiro Kamatani , Sharon L Kardia , Masaru Koido , Michiaki Kubo , Leslie Lange , Jin-Moo Lee , Robin Lemmens , Christopher R Levi , Jiang Li , Liming Li , Kuang Lin , Haley Lopez , Sothear Luke , Jane Maguire , Patrick F McArdle , Caitrin W McDonough , James F Meschia , Tiina Metso , Martina Muller-Nurasyid , Timothy D O'Connor , Martin O'Donnell , Leema R Peddareddygari , Joanna Pera , James A Perry , Annette Peters , Jukka Putaala , Debashree Ray , Kathryn Rexrode , Marta Ribases , Jonathan Rosand , Peter M Rothwell , Tatjana Rundek , Kathleen A Ryan , Ralph L Sacco , Veikko Salomaa , Cristina Sanchez-Mora , Reinhold Schmidt , Pankaj Sharma , Agnieszka Slowik , Jennifer A Smith , Nicholas L Smith , Sylvia Wassertheil-Smoller , Martin Soederholm , O C Stine , Daniel Strbian , Cathie L Sudlow , Turgut Tatlisumak , Chikashi Terao , Vincent Thijs , Nuria P Torres-Aguila , David-Alexandre Tregouet , Anil M Tuladhar , Jan H Veldink , Robin G Walters , David R Weir , Daniel Woo , Bradford B Worrall , Charles C Hong , Owen Ross , Ramin Zand , Frank-Erik de Leeuw , Arne G Lindgren , Guillaume Pare , Christopher D Anderson , Hugh S Markus , Christina Jern , Rainer Malik , Martin Dichgans , Braxton D Mitchell , Steven J Kittner , Auteur inconnu

Associations of genetically predicted IL-6 signaling with cardiovascular disease risk across population subgroups.

BMC medicine

Avec: Marios K Georgakis , Rainer Malik , Tom G Richardson , Joanna M M Howson , Christopher D Anderson , Stephen Burgess , G Kees Hovingh , Martin Dichgans , Dipender Gill

Disentangling the effects of Alzheimer's and small vessel disease on white matter fibre tracts.

Brain : a journal of neurology

Avec: Anna Dewenter , Mina A Jacob , Mengfei Cai , Benno Gesierich , Paul Hager , Anna Kopczak , Davina Biel , Michael Ewers , Anil M Tuladhar , Frank-Erik de Leeuw , Martin Dichgans , Nicolai Franzmeier , Marco Duering , Auteur inconnu

Zooming in on cerebral small vessel function in small vessel diseases with 7T MRI: Rationale and design of the "ZOOM@SVDs" study.

Cerebral circulation - cognition and behavior

Avec: Hilde van den Brink , Anna Kopczak , Tine Arts , Laurien Onkenhout , Jeroen C W Siero , Jaco J M Zwanenburg , Marco Duering , Gordon W Blair , Fergus N Doubal , Michael S Stringer , Michael J Thrippleton , Hugo J Kuijf , Alberto de Luca , Jeroen Hendrikse , Joanna M Wardlaw , Martin Dichgans , Geert Jan Biessels , Auteur inconnu

European Stroke Organisation (ESO) guideline on pharmacological interventions for long-term secondary prevention after ischaemic stroke or transient ischaemic attack.

European stroke journal

Avec: Jesse Dawson , Yannick Béjot , Louisa M Christensen , Gian Marco De Marchis , Martin Dichgans , Guri Hagberg , Mirjam R Heldner , Haralampos Milionis , Linxin Li , Francesca Romana Pezzella , Martin Taylor Rowan , Cristina Tiu , Alastair Webb

Delivery of acute ischaemic stroke treatments in the European region in 2019 and 2020.

European stroke journal

Avec: Diana Aguiar de Sousa , Arlene Wilkie , Bo Norrving , Chris Macey , Claudio Bassetti , Cristina Tiu , Greg Roth , Grethe Lunde , Hanne Christensen , Jens Fiehler , Francesca Romana Pezzella , Martin Dichgans , Melinda B Roaldsen , Peter Kelly , Robert Mikulik , Simona Sacco , Valeria Caso , Urs Fischer , Auteur inconnu

Carriers of rare damaging

medRxiv : the preprint server for health sciences

Avec: Marios K Georgakis , Rainer Malik , Natalie R Hasbani , Gabrielle Shakt , Alanna C Morrison , Noah L Tsao , Renae Judy , Braxton D Mitchell , Huichun Xu , May E Montasser , Ron Do , Eimear E Kenny , Ruth J F Loos , James G Terry , John Jeffrey Carr , Joshua C Bis , Bruce M Psaty , W T Longstreth , Kendra A Young , Sharon M Lutz , Michael H Cho , Jai Broome , Alyna T Khan , Fei Fei Wang , Nancy Heard-Costa , Sudha Seshadri , Ramachandran S Vasan , Nicholette D Palmer , Barry I Freedman , Donald W Bowden , Lisa R Yanek , Brian G Kral , Lewis C Becker , Patricia A Peyser , Lawrence F Bielak , Farah Ammous , April P Carson , Michael E Hall , Laura M Raffield , Stephen S Rich , Wendy S Post , Russel P Tracy , Kent D Taylor , Xiuqing Guo , Michael C Mahaney , Joanne E Curran , John Blangero , Shoa L Clarke , Jeffrey W Haessler , Yao Hu , Themistocles L Assimes , Charles Kooperberg , Scott M Damrauer , Jerome I Rotter , Paul S de Vries , Martin Dichgans

ApoE4 and Connectivity-Mediated Spreading of Tau Pathology at Lower Amyloid Levels.

JAMA neurology

Avec: Anna Steward , Davina Biel , Anna Dewenter , Sebastian Roemer , Fabian Wagner , Amir Dehsarvi , Saima Rathore , Diana Otero Svaldi , Ixavier Higgins , Matthias Brendel , Martin Dichgans , Sergey Shcherbinin , Michael Ewers , Nicolai Franzmeier

Genetic Insights on the Relation of Vascular Risk Factors and Cervical Artery Dissection.

Journal of the American College of Cardiology

Avec: Quentin Le Grand , Leslie Ecker Ferreira , Tiina M Metso , Sabrina Schilling , Turgut Tatlisumak , Caspar Grond-Ginsbach , Stefan T Engelter , Philippe Lyrer , Jennifer J Majersik , Bradford B Worrall , Andrew M Southerland , Hugh S Markus , Mark Lathrop , Vincent Thijs , Didier Leys , Philippe Amouyel , Jean Dallongeville , Martin Dichgans , Alessandro Pezzini , Anna Bersano , Muralidharan Sargurupremraj , Stéphanie Debette , Auteur inconnu

Proteomics of mouse brain endothelium uncovers dysregulation of vesicular transport pathways during aging.

Nature aging

Avec: Katalin Todorov-Völgyi , Judit González-Gallego , Stephan A Müller , Nathalie Beaufort , Rainer Malik , Martina Schifferer , Mihail Ivilinov Todorov , Dennis Crusius , Sophie Robinson , Andree Schmidt , Jakob Körbelin , Florence Bareyre , Ali Ertürk , Christian Haass , Mikael Simons , Dominik Paquet , Stefan F Lichtenthaler , Martin Dichgans

KCNA2 IgG autoimmunity in neuropsychiatric diseases.

Brain, behavior, and immunity

Avec: Friederike A Arlt , Ramona Miske , Marie-Luise Machule , Peter Broegger Christensen , Swantje Mindorf , Bianca Teegen , Kathrin Borowski , Maria Buthut , Rosa Rößling , Elisa Sanchez-Sendin , Scott van Hoof , César Cordero-Gómez , Isabel Bünger , Helena Radbruch , Andrea Kraft , Ilya Ayzenberg , Jaqueline Klausewitz , Niels Hansen , Charles Timäus , Peter Körtvelyessy , Thomas Postert , Kirsten Baur-Seack , Constanze Rost , Robert Brunkhorst , Kathrin Doppler , Niklas Haigis , Gerhard Hamann , Albrecht Kunze , Alexandra Stützer , Matthias Maschke , Nico Melzer , Felix Rosenow , Kai Siebenbrodt , Christian Stenør , Martin Dichgans , Marios K Georgakis , Rong Fang , Gabor C Petzold , Michael Görtler , Inga Zerr , Silke Wunderlich , Ivan Mihaljevic , Paul Turko , Marianne Schmidt Ettrup , Emilie Buchholz , Helle Foverskov Rasmussen , Mahoor Nasouti , Ivan Talucci , Hans M Maric , Stefan H Heinemann , Matthias Endres , Lars Komorowski , Harald Prüss , Auteur inconnu

Innate immune memory after brain injury drives inflammatory cardiac dysfunction.

Cell

Avec: Alba Simats , Sijia Zhang , Denise Messerer , Faye Chong , Sude Beşkardeş , Aparna Sharma Chivukula , Jiayu Cao , Simon Besson-Girard , Felipe A Montellano , Caroline Morbach , Olga Carofiglio , Alessio Ricci , Stefan Roth , Gemma Llovera , Rashween Singh , Yiming Chen , Severin Filser , Nikolaus Plesnila , Christian Braun , Hannah Spitzer , Ozgun Gokce , Martin Dichgans , Peter U Heuschmann , Kinta Hatakeyama , Eduardo Beltrán , Sebastian Clauss , Boyan Bonev , Christian Schulz , Arthur Liesz

DNA-sensing inflammasomes cause recurrent atherosclerotic stroke.

Nature

Avec: Jiayu Cao , Stefan Roth , Sijia Zhang , Anna Kopczak , Samira Mami , Yaw Asare , Marios K Georgakis , Denise Messerer , Amit Horn , Ruth Shemer , Charlene Jacqmarcq , Audrey Picot , Jack P Green , Christina Schlegl , Xinghai Li , Lukas Tomas , Alexander Dutsch , Thomas G Liman , Matthias Endres , Saskia R Wernsdorf , Christina Fürle , Olga Carofiglio , Jie Zhu , David Brough , Auteur inconnu , Veit Hornung , Martin Dichgans , Denis Vivien , Christian Schulz , Yuval Dor , Steffen Tiedt , Hendrik B Sager , Gerrit M Grosse , Arthur Liesz

Serum anti-NMDA receptor antibodies are linked to memory impairment 12 months after stroke.

Molecular psychiatry

Avec: Friederike A Arlt , Pia S Sperber , Regina von Rennenberg , Pimrapat Gebert , Bianca Teegen , Marios K Georgakis , Rong Fang , Anna Dewenter , Michael Görtler , Gabor C Petzold , Silke Wunderlich , Inga Zerr , Martin Dichgans , Harald Prüss , Matthias Endres , Auteur inconnu

Mendelian Randomization Study of Obesity and Cerebrovascular Disease.

Annals of neurology

Avec: Sandro Marini , Jordi Merino , Bailey E Montgomery , Rainer Malik , Catherine L Sudlow , Martin Dichgans , Jose C Florez , Jonathan Rosand , Dipender Gill , Christopher D Anderson , Auteur inconnu

Heritable and non-heritable uncommon causes of stroke.

Journal of neurology

Avec: A Bersano , M Kraemer , A Burlina , M Mancuso , J Finsterer , S Sacco , C Salvarani , L Caputi , H Chabriat , S Lesnik Oberstein , A Federico , E Tournier Lasserve , D Hunt , M Dichgans , M Arnold , S Debette , H S Markus

Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.

Stroke

Avec: Keith L Keene , Hyacinth I Hyacinth , Joshua C Bis , Steven J Kittner , Braxton D Mitchell , Yu-Ching Cheng , Guillaume Pare , Michael Chong , Martin O'Donnell , James F Meschia , Wei-Min Chen , Michèle M Sale , Stephen S Rich , Mike A Nalls , Alan B Zonderman , Michele K Evans , James G Wilson , Adolfo Correa , Hugh S Markus , Matthew Traylor , Cathryn M Lewis , Cara L Carty , Alexander Reiner , Jeff Haessler , Carl D Langefeld , Rebecca Gottesman , Thomas H Mosley , Daniel Woo , Kristine Yaffe , YongMei Liu , William T Longstreth , Bruce M Psaty , Charles Kooperberg , Leslie A Lange , Ralph Sacco , Tatjana Rundek , Jin-Moo Lee , Carlos Cruchaga , Karen L Furie , Donna K Arnett , Oscar R Benavente , Raji P Grewal , Leema Reddy Peddareddygari , Martin Dichgans , Rainer Malik , Bradford B Worrall , Myriam Fornage , Auteur inconnu

Broad phenotype of cysteine-altering

Neurology

Avec: Julie W Rutten , Remco J Hack , Marco Duering , Gido Gravesteijn , Johannes G Dauwerse , Maurice Overzier , Erik B van den Akker , Eline Slagboom , Henne Holstege , Kwangsik Nho , Andrew Saykin , Martin Dichgans , Rainer Malik , Saskia A J Lesnik Oberstein

Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing.

Cell reports

Avec: Isabel Weisheit , Joseph A Kroeger , Rainer Malik , Julien Klimmt , Dennis Crusius , Angelika Dannert , Martin Dichgans , Dominik Paquet

Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability.

Circulation research

Avec: Yaw Asare , Thomas A Campbell-James , Yury Bokov , Lydia Luya Yu , Matthias Prestel , Omar El Bounkari , Stefan Roth , Remco T A Megens , Tobias Straub , Kyra Thomas , Guangyao Yan , Melanie Schneider , Natalie Ziesch , Steffen Tiedt , Carlos Silvestre-Roig , Quinte Braster , Yishu Huang , Manuela Schneider , Rainer Malik , Christof Haffner , Arthur Liesz , Oliver Soehnlein , Jürgen Bernhagen , Martin Dichgans

PRediction of acute coronary syndrome in acute ischemic StrokE (PRAISE) - protocol of a prospective, multicenter trial with central reading and predefined endpoints.

BMC neurology

Avec: Christian H Nolte , Regina von Rennenberg , Simon Litmeier , Jan F Scheitz , David M Leistner , Stephan Blankenberg , Martin Dichgans , Hugo Katus , Gabor C Petzold , Burkert Pieske , Vera Regitz-Zagrosek , Karl Wegscheider , Andreas M Zeiher , Ulf Landmesser , Matthias Endres

Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID-19 pandemic, now and in the future.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Avec: Vincent C T Mok , Sarah Pendlebury , Adrian Wong , Suvarna Alladi , Lisa Au , Philip M Bath , Geert Jan Biessels , Christopher Chen , Charlotte Cordonnier , Martin Dichgans , Jacqueline Dominguez , Philip B Gorelick , SangYun Kim , Timothy Kwok , Steven M Greenberg , Jianping Jia , Rajesh Kalaria , Miia Kivipelto , Kandiah Naegandran , Linda C W Lam , Bonnie Yin Ka Lam , Allen T C Lee , Hugh S Markus , John O'Brien , Ming-Chyi Pai , Leonardo Pantoni , Perminder Sachdev , Ingmar Skoog , Eric E Smith , Velandai Srikanth , Guk-Hee Suh , Joanna Wardlaw , Ho Ko , Sandra E Black , Philip Scheltens

Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment.

International journal of stroke : official journal of the International Stroke Society

Avec: Anna C Alegiani , Franziska Dorn , Moriz Herzberg , Frank A Wollenweber , Lars Kellert , Eberhard Siebert , Christian H Nolte , Regina von Rennenberg , Elke Hattingen , Gabor C Petzold , Felix J Bode , Waltraud Pfeilschifter , Jan H Schäfer , Marlies Wagner , Joachim Röther , Bernd Eckert , Peter Kraft , Mirko Pham , Tobias Boeckh-Behrens , Silke Wunderlich , Kathleen Bernkopf , Arno Reich , Martin Wiesmann , Anastasios Mpotsaris , Marios Psychogios , Jan Liman , Ilko Maier , Jörg Berrouschot , Albrecht Bormann , Volker Limmroth , Joachim Spreer , Martina Petersen , Lars Krause , Stephan Lowens , Christoffer Kraemer , Sarah Zweynert , Kristin S Lange , Sven Thonke , Andreas Kastrup , Panagiotis Papanagiotou , Burkhard Alber , Michael Braun , Jens Fiehler , Christian Gerloff , Martin Dichgans , Götz Thomalla

Genome-wide association study of cerebral small vessel disease reveals established and novel loci.

Brain : a journal of neurology

Avec: Jaeyoon Chung , Sandro Marini , Joanna Pera , Bo Norrving , Jordi Jimenez-Conde , Jaume Roquer , Israel Fernandez-Cadenas , David L Tirschwell , Magdy Selim , Devin L Brown , Scott L Silliman , Bradford B Worrall , James F Meschia , Stacie Demel , Steven M Greenberg , Agnieszka Slowik , Arne Lindgren , Reinhold Schmidt , Matthew Traylor , Muralidharan Sargurupremraj , Steffen Tiedt , Rainer Malik , Stéphanie Debette , Martin Dichgans , Carl D Langefeld , Daniel Woo , Jonathan Rosand , Christopher D Anderson

Contribution of acute infarcts to cerebral small vessel disease progression.

Annals of neurology

Avec: Annemieke Ter Telgte , Kim Wiegertjes , Benno Gesierich , José P Marques , Mathias Huebner , Jabke J de Klerk , Floris H B M Schreuder , Miguel A Araque Caballero , Hugo J Kuijf , David G Norris , Catharina J M Klijn , Martin Dichgans , Anil M Tuladhar , Marco Duering , Frank-Erik de Leeuw

Within-lesion heterogeneity of subcortical DWI lesion evolution, and stroke outcome: A voxel-based analysis.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Avec: Marco Duering , Ruth Adam , Frank A Wollenweber , Anna Bayer-Karpinska , Ebru Baykara , Leidy Y Cubillos-Pinilla , Benno Gesierich , Miguel Á Araque Caballero , Sophia Stoecklein , Michael Ewers , Ofer Pasternak , Martin Dichgans

A prospective study of serum metabolites and risk of ischemic stroke.

Neurology

Avec: Daokun Sun , Steffen Tiedt , Bing Yu , Xueqiu Jian , Rebecca F Gottesman , Thomas H Mosley , Eric Boerwinkle , Martin Dichgans , Myriam Fornage

Prediction of Long-term Cognitive Functions after Minor Stroke, Using Functional Connectivity.

Neurology

Avec: Renaud Lopes , Clément Bournonville , Grégory Kuchcinski , Thibaut Dondaine , Anne-Marie Mendyk , Romain Viard , Jean-Pierre Pruvo , Hilde Hénon , Marios K Georgakis , Marco Duering , Martin Dichgans , Charlotte Cordonnier , Xavier Leclerc , Régis Bordet

Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality: A Meta-analysis of Population-Based Studies.

JAMA cardiology

Avec: Marios K Georgakis , James A de Lemos , Colby Ayers , Biqi Wang , Harry Björkbacka , Tiberiu A Pana , Barbara Thorand , Caroline Sun , Lana Fani , Rainer Malik , Josée Dupuis , Gunnar Engström , Marju Orho-Melander , Olle Melander , S Matthijs Boekholdt , Astrid Zierer , Mohamed A Elhadad , Wolfgang Koenig , Christian Herder , Ron C Hoogeveen , Maryam Kavousi , Christie M Ballantyne , Annette Peters , Phyo K Myint , Jan Nilsson , Emelia J Benjamin , Martin Dichgans

Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting.

Nature communications

Avec: Christos Kontos , Omar El Bounkari , Christine Krammer , Dzmitry Sinitski , Kathleen Hille , Chunfang Zan , Guangyao Yan , Sijia Wang , Ying Gao , Markus Brandhofer , Remco T A Megens , Adrian Hoffmann , Jessica Pauli , Yaw Asare , Simona Gerra , Priscila Bourilhon , Lin Leng , Hans-Henning Eckstein , Wolfgang E Kempf , Jaroslav Pelisek , Ozgun Gokce , Lars Maegdefessel , Richard Bucala , Martin Dichgans , Christian Weber , Aphrodite Kapurniotu , Jürgen Bernhagen

Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration.

Molecular neurodegeneration

Avec: Nicolai Franzmeier , M Suárez-Calvet , Lukas Frontzkowski , Annah Moore , Timothy J Hohman , Estrella Morenas-Rodriguez , Brigitte Nuscher , Leslie Shaw , John Q Trojanowski , Martin Dichgans , Gernot Kleinberger , Christian Haass , Michael Ewers , Auteur inconnu

Population impact of different hypertension management guidelines based on the prospective population-based Heinz Nixdorf Recall study.

BMJ open

Avec: Janine Gronewold , Rene Kropp , Nils Lehmann , Andreas Stang , Amir A Mahabadi , Christian Weimar , Martin Dichgans , Susanne Moebus , Knut Kröger , Barbara Hoffmann , Karl-Heinz Jöckel , Raimund Erbel , Dirk M Hermann , Auteur inconnu

Monocyte-Chemoattractant Protein-1 Levels in Human Atherosclerotic Lesions Associate With Plaque Vulnerability.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Marios K Georgakis , Sander W van der Laan , Yaw Asare , Joost M Mekke , Saskia Haitjema , Arjan H Schoneveld , Saskia C A de Jager , Nick S Nurmohamed , Jeffrey Kroon , Erik S G Stroes , Dominique P V de Kleijn , Gert J de Borst , Lars Maegdefessel , Oliver Soehnlein , Gerard Pasterkamp , Martin Dichgans

Genetically Proxied Inhibition of Coagulation Factors and Risk of Cardiovascular Disease: A Mendelian Randomization Study.

Journal of the American Heart Association

Avec: Shuai Yuan , Stephen Burgess , Mike Laffan , Amy M Mason , Martin Dichgans , Dipender Gill , Susanna C Larsson

Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors.

Nature genetics

Avec: Mark K Bakker , Rick A A van der Spek , Wouter van Rheenen , Sandrine Morel , Romain Bourcier , Isabel C Hostettler , Varinder S Alg , Kristel R van Eijk , Masaru Koido , Masato Akiyama , Chikashi Terao , Koichi Matsuda , Robin G Walters , Kuang Lin , Liming Li , Iona Y Millwood , Zhengming Chen , Guy A Rouleau , Sirui Zhou , Kristiina Rannikmäe , Cathie L M Sudlow , Henry Houlden , Leonard H van den Berg , Christian Dina , Olivier Naggara , Jean-Christophe Gentric , Eimad Shotar , François Eugène , Hubert Desal , Bendik S Winsvold , Sigrid Børte , Marianne Bakke Johnsen , Ben M Brumpton , Marie Søfteland Sandvei , Cristen J Willer , Kristian Hveem , John-Anker Zwart , W M Monique Verschuren , Christoph M Friedrich , Sven Hirsch , Sabine Schilling , Jérôme Dauvillier , Olivier Martin , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Gregory T Jones , Matthew J Bown , Nerissa U Ko , Helen Kim , Jonathan R I Coleman , Gerome Breen , Jonathan G Zaroff , Catharina J M Klijn , Rainer Malik , Martin Dichgans , Muralidharan Sargurupremraj , Turgut Tatlisumak , Philippe Amouyel , Stéphanie Debette , Gabriel J E Rinkel , Bradford B Worrall , Joanna Pera , Agnieszka Slowik , Emília I Gaál-Paavola , Mika Niemelä , Juha E Jääskeläinen , Mikael von Und Zu Fraunberg , Antti Lindgren , Joseph P Broderick , David J Werring , Daniel Woo , Richard Redon , Philippe Bijlenga , Yoichiro Kamatani , Jan H Veldink , Ynte M Ruigrok

Shared genetic background between SARS-CoV-2 infection and large artery stroke.

International journal of stroke : official journal of the International Stroke Society

Avec: Livia Parodi , Evangelos Pavlos Myserlis , Jaeyoon Chung , Marios K Georgakis , Ernst Mayerhofer , Jonathan Henry , Bailey E Montgomery , Mandy Moy , Huichun Xu , Rainer Malik , Carl D Langefeld , Martin Dichgans , Auteur inconnu , Daniel Woo , Jonathan Rosand , Christopher D Anderson , Auteur inconnu

Subjective cognitive decline and stage 2 of Alzheimer disease in patients from memory centers.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Avec: Frank Jessen , Steffen Wolfsgruber , Luca Kleineindam , Annika Spottke , Slawek Altenstein , Claudia Bartels , Moritz Berger , Frederic Brosseron , Marcel Daamen , Martin Dichgans , Laura Dobisch , Michael Ewers , Friederike Fenski , Klaus Fliessbach , Silka D Freiesleben , Wenzel Glanz , Doreen Görß , Selim Gürsel , Daniel Janowitz , Ingo Kilimann , Xenia Kobeleva , Andrea Lohse , Franziska Maier , Coraline Metzger , Matthias Munk , Lukas Preis , Carolin Sanzenbacher , Eike Spruth , Boris Rauchmann , Ruth Vukovich , Renat Yakupov , Anne-Sophie Weyrauch , Gabriel Ziegler , Matthias Schmid , Christoph Laske , Robert Perneczky , Anja Schneider , Jens Wiltfang , Stefan Teipel , Katharina Bürger , Josef Priller , Oliver Peters , Alfredo Ramirez , Henning Boecker , Michael T Heneka , Michael Wagner , Emrah Düzel

Genetically predicted on-statin LDL response is associated with higher intracerebral haemorrhage risk.

Brain : a journal of neurology

Avec: Ernst Mayerhofer , Rainer Malik , Livia Parodi , Stephen Burgess , Andreas Harloff , Martin Dichgans , Jonathan Rosand , Christopher D Anderson , Marios K Georgakis

Prevalence and Significance of the Vessel-Cluster Sign on Susceptibility-Weighted Imaging in Patients With Severe Small Vessel Disease.

Neurology

Avec: Salvatore Rudilosso , Ernest Chui , Michael S Stringer , Michael Thrippleton , Francesca Chappell , Gordon Blair , Daniela Jaime GarcÃa , Fergus Doubal , Iona Hamilton , Anna Kopczak , Michael Ingrish , Danielle Kerkhofs , Walter H Backes , Julie Staals , Robert van Oostenbrugge , Marco Duering , Martin Dichgans , Joanna M Wardlaw , Auteur inconnu

Framework for Clinical Trials in Cerebral Small Vessel Disease (FINESSE): A Review.

JAMA neurology

Avec: Hugh S Markus , Wiesje M van Der Flier , Eric E Smith , Philip Bath , Geert Jan Biessels , Emily Briceno , Amy Brodtman , Hugues Chabriat , Christopher Chen , Frank-Erik de Leeuw , Marco Egle , Aravind Ganesh , Marios K Georgakis , Rebecca F Gottesman , Sun Kwon , Lenore Launer , Vincent Mok , John O'Brien , Lois Ottenhoff , Sarah Pendlebury , Edo Richard , Perminder Sachdev , Reinhold Schmidt , Melanie Springer , Stefan Tiedt , Joanna M Wardlaw , Ana Verdelho , Alastair Webb , David Werring , Marco Duering , Deborah Levine , Martin Dichgans

Earlier Alzheimer's disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading.

Nature communications

Avec: Lukas Frontzkowski , Michael Ewers , Matthias Brendel , Davina Biel , Rik Ossenkoppele , Paul Hager , Anna Steward , Anna Dewenter , Sebastian Römer , Anna Rubinski , Katharina Buerger , Daniel Janowitz , Alexa Pichet Binette , Ruben Smith , Olof Strandberg , Niklas Mattsson Carlgren , Martin Dichgans , Oskar Hansson , Nicolai Franzmeier

Stroke genetics informs drug discovery and risk prediction across ancestries.

Nature

Avec: Aniket Mishra , Rainer Malik , Tsuyoshi Hachiya , Tuuli Jürgenson , Shinichi Namba , Daniel C Posner , Frederick K Kamanu , Masaru Koido , Quentin Le Grand , Mingyang Shi , Yunye He , Marios K Georgakis , Ilana Caro , Kristi Krebs , Yi-Ching Liaw , Felix C Vaura , Kuang Lin , Bendik Slagsvold Winsvold , Vinodh Srinivasasainagendra , Livia Parodi , Hee-Joon Bae , Ganesh Chauhan , Michael R Chong , Liisa Tomppo , Rufus Akinyemi , Gennady V Roshchupkin , Naomi Habib , Yon Ho Jee , Jesper Qvist Thomassen , Vida Abedi , Jara Cárcel-Márquez , Marianne Nygaard , Hampton L Leonard , Chaojie Yang , Ekaterina Yonova-Doing , Maria J Knol , Adam J Lewis , Renae L Judy , Tetsuro Ago , Philippe Amouyel , Nicole D Armstrong , Mark K Bakker , Traci M Bartz , David A Bennett , Joshua C Bis , Constance Bordes , Sigrid Børte , Anael Cain , Paul M Ridker , Kelly Cho , Zhengming Chen , Carlos Cruchaga , John W Cole , Phil L de Jager , Rafael de Cid , Matthias Endres , Leslie E Ferreira , Mirjam I Geerlings , Natalie C Gasca , Vilmundur Gudnason , Jun Hata , Jing He , Alicia K Heath , Yuk-Lam Ho , Aki S Havulinna , Jemma C Hopewell , Hyacinth I Hyacinth , Michael Inouye , Mina A Jacob , Christina E Jeon , Christina Jern , Masahiro Kamouchi , Keith L Keene , Takanari Kitazono , Steven J Kittner , Takahiro Konuma , Amit Kumar , Paul Lacaze , Lenore J Launer , Keon-Joo Lee , Kaido Lepik , Jiang Li , Liming Li , Ani Manichaikul , Hugh S Markus , Nicholas A Marston , Thomas Meitinger , Braxton D Mitchell , Felipe A Montellano , Takayuki Morisaki , Thomas H Mosley , Mike A Nalls , Børge G Nordestgaard , Martin J O'Donnell , Yukinori Okada , N Charlotte Onland-Moret , Bruce Ovbiagele , Annette Peters , Bruce M Psaty , Stephen S Rich , Jonathan Rosand , Marc S Sabatine , Ralph L Sacco , Danish Saleheen , Else Charlotte Sandset , Veikko Salomaa , Muralidharan Sargurupremraj , Makoto Sasaki , Claudia L Satizabal , Carsten O Schmidt , Atsushi Shimizu , Nicholas L Smith , Kelly L Sloane , Yoichi Sutoh , Yan V Sun , Kozo Tanno , Steffen Tiedt , Turgut Tatlisumak , Nuria P Torres-Aguila , Hemant K Tiwari , David-Alexandre Trégouët , Stella Trompet , Anil Man Tuladhar , Anne Tybjærg-Hansen , Marion van Vugt , Riina Vibo , Shefali S Verma , Kerri L Wiggins , Patrik Wennberg , Daniel Woo , Peter W F Wilson , Huichun Xu , Qiong Yang , Kyungheon Yoon , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Iona Y Millwood , Christian Gieger , Toshiharu Ninomiya , Hans J Grabe , J Wouter Jukema , Ina L Rissanen , Daniel Strbian , Young Jin Kim , Pei-Hsin Chen , Ernst Mayerhofer , Joanna M M Howson , Marguerite R Irvin , Hieab Adams , Sylvia Wassertheil-Smoller , Kaare Christensen , Mohammad A Ikram , Tatjana Rundek , Bradford B Worrall , G Mark Lathrop , Moeen Riaz , Eleanor M Simonsick , Janika Kõrv , Paulo H C França , Ramin Zand , Kameshwar Prasad , Ruth Frikke-Schmidt , Frank-Erik de Leeuw , Thomas Liman , Karl Georg Haeusler , Ynte M Ruigrok , Peter Ulrich Heuschmann , W T Longstreth , Keum Ji Jung , Lisa Bastarache , Guillaume Paré , Scott M Damrauer , Daniel I Chasman , Jerome I Rotter , Christopher D Anderson , John-Anker Zwart , Teemu J Niiranen , Myriam Fornage , Yung-Po Liaw , Sudha Seshadri , Israel Fernández-Cadenas , Robin G Walters , Christian T Ruff , Mayowa O Owolabi , Jennifer E Huffman , Lili Milani , Yoichiro Kamatani , Martin Dichgans , Stephanie Debette

Tipping points in neurodegeneration.

Neuron

Avec: Mikael Simons , Johannes Levin , Martin Dichgans

Distinct molecular profiles of skull bone marrow in health and neurological disorders.

Cell

Avec: Zeynep Ilgin Kolabas , Louis B Kuemmerle , Robert Perneczky , Benjamin Förstera , Selin Ulukaya , Mayar Ali , Saketh Kapoor , Laura M Bartos , Maren Büttner , Ozum Sehnaz Caliskan , Zhouyi Rong , Hongcheng Mai , Luciano Höher , Denise Jeridi , Muge Molbay , Igor Khalin , Ioannis K Deligiannis , Moritz Negwer , Kenny Roberts , Alba Simats , Olga Carofiglio , Mihail I Todorov , Izabela Horvath , Furkan Ozturk , Selina Hummel , Gloria Biechele , Artem Zatcepin , Marcus Unterrainer , Johannes Gnörich , Jay Roodselaar , Joshua Shrouder , Pardis Khosravani , Benjamin Tast , Lisa Richter , Laura Díaz-Marugán , Doris Kaltenecker , Laurin Lux , Ying Chen , Shan Zhao , Boris-Stephan Rauchmann , Michael Sterr , Ines Kunze , Karen Stanic , Vanessa W Y Kan , Simon Besson-Girard , Sabrina Katzdobler , Carla Palleis , Julia Schädler , Johannes C Paetzold , Sabine Liebscher , Anja E Hauser , Ozgun Gokce , Heiko Lickert , Hanno Steinke , Corinne Benakis , Christian Braun , Celia P Martinez-Jimenez , Katharina Buerger , Nathalie L Albert , Günter Höglinger , Johannes Levin , Christian Haass , Anna Kopczak , Martin Dichgans , Joachim Havla , Tania Kümpfel , Martin Kerschensteiner , Martina Schifferer , Mikael Simons , Arthur Liesz , Natalie Krahmer , Omer A Bayraktar , Nicolai Franzmeier , Nikolaus Plesnila , Suheda Erener , Victor G Puelles , Claire Delbridge , Harsharan Singh Bhatia , Farida Hellal , Markus Elsner , Ingo Bechmann , Benjamin Ondruschka , Matthias Brendel , Fabian J Theis , Ali Erturk

Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex.

Nature communications

Avec: Christina Koupourtidou , Veronika Schwarz , Hananeh Aliee , Simon Frerich , Judith Fischer-Sternjak , Riccardo Bocchi , Tatiana Simon-Ebert , Xianshu Bai , Swetlana Sirko , Frank Kirchhoff , Martin Dichgans , Magdalena Götz , Fabian J Theis , Jovica Ninkovic

Type 1 Myocardial Infarction in Patients With Acute Ischemic Stroke.

JAMA neurology

Avec: Christian H Nolte , Regina von Rennenberg , Simon Litmeier , David M Leistner , Kristina Szabo , Stefan Baumann , Annerose Mengel , Dominik Michalski , Timo Siepmann , Stephan Blankenberg , Gabor C Petzold , Martin Dichgans , Hugo Katus , Burkert Pieske , Vera Regitz-Zagrosek , Tim Bastian Braemswig , Ida Rangus , Amra Pepic , Eik Vettorazzi , Andreas M Zeiher , Jan F Scheitz , Karl Wegscheider , Ulf Landmesser , Matthias Endres

Assessment of Small Vessel Function Using 7T MRI in Patients With Sporadic Cerebral Small Vessel Disease: The ZOOM@SVDs Study.

Neurology

Avec: Hilde Van Den Brink , Stanley Pham , Jeroen C Siero , Tine Arts , Laurien Onkenhout , Hugo Kuijf , Jeroen Hendrikse , Joanna M Wardlaw , Martin Dichgans , Jaco J Zwanenburg , Geert Jan Biessels

Rational correction of pathogenic conformational defects in HTRA1.

Nature communications

Avec: Nathalie Beaufort , Linda Ingendahl , Melisa Merdanovic , Andree Schmidt , David Podlesainski , Tim Richter , Thorben Neumann , Michael Kuszner , Ingrid R Vetter , Patricia Stege , Steven G Burston , Anto Filipovic , Yasser B Ruiz-Blanco , Kenny Bravo-Rodriguez , Joel Mieres-Perez , Christine Beuck , Stephan Uebel , Monika Zobawa , Jasmin Schillinger , Rainer Malik , Katalin Todorov-Völgyi , Juliana Rey , Annabell Roberti , Birte Hagemeier , Benedikt Wefers , Stephan A Müller , Wolfgang Wurst , Elsa Sanchez-Garcia , Alexander Zimmermann , Xiao-Yu Hu , Tim Clausen , Robert Huber , Stefan F Lichtenthaler , Carsten Schmuck , Michael Giese , Markus Kaiser , Michael Ehrmann , Martin Dichgans

Genetically proxied HTRA1 protease activity and circulating levels independently predict risk of ischemic stroke and coronary artery disease.

Nature cardiovascular research

Avec: Rainer Malik , Nathalie Beaufort , Jiang Li , Koki Tanaka , Marios K Georgakis , Yunye He , Masaru Koido , Chikashi Terao , BioBank Japan , Christopher D Anderson , Yoichiro Kamatani , Ramin Zand , Martin Dichgans

Genetically Predicted Blood Pressure Across the Lifespan: Differential Effects of Mean and Pulse Pressure on Stroke Risk.

Hypertension (Dallas, Tex. : 1979)

Avec: Marios K Georgakis , Dipender Gill , Rainer Malik , Athanase D Protogerou , Alastair J S Webb , Martin Dichgans

Genetically Predicted Midlife Blood Pressure and Coronary Artery Disease Risk: Mendelian Randomization Analysis.

Journal of the American Heart Association

Avec: Dipender Gill , Marios K Georgakis , Verena Zuber , Ville Karhunen , Stephen Burgess , Rainer Malik , Martin Dichgans

Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.

EMBO molecular medicine

Avec: Michael Ewers , Gloria Biechele , Marc Suárez-Calvet , Christian Sacher , Tanja Blume , Estrella Morenas-Rodriguez , Yuetiva Deming , Laura Piccio , Carlos Cruchaga , Gernot Kleinberger , Leslie Shaw , John Q Trojanowski , Jochen Herms , Martin Dichgans , Auteur inconnu , Matthias Brendel , Christian Haass , Nicolai Franzmeier

Circulating Metabolites Differentiate Acute Ischemic Stroke from Stroke Mimics.

Annals of neurology

Avec: Steffen Tiedt , Stefan Brandmaier , Hanna Kollmeier , Marco Duering , Anna Artati , Jerzy Adamski , Matthias Klein , Thomas Liebig , Lesca M Holdt , Daniel Teupser , Rui Wang-Sattler , Edzard Schwedhelm , Christian Gieger , Martin Dichgans

Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Avec: Sofia Finsterwalder , Naomi Vlegels , Benno Gesierich , Miguel Á Araque Caballero , Nick A Weaver , Nicolai Franzmeier , Marios K Georgakis , Marek J Konieczny , Huiberdina L Koek , Auteur inconnu , Celeste M Karch , Neill R Graff-Radford , Stephen Salloway , Hwamee Oh , Ricardo F Allegri , Jasmeer P Chhatwal , Auteur inconnu , Frank Jessen , Emrah Düzel , Laura Dobisch , Coraline Metzger , Oliver Peters , Enise I Incesoy , Josef Priller , Eike J Spruth , Anja Schneider , Klaus Fließbach , Katharina Buerger , Daniel Janowitz , Stefan J Teipel , Ingo Kilimann , Christoph Laske , Martina Buchmann , Michael T Heneka , Frederic Brosseron , Annika Spottke , Nina Roy , Birgit Ertl-Wagner , Klaus Scheffler , Auteur inconnu , Auteur inconnu , Sang Won Seo , Yeshin Kim , Duk L Na , Hee Jin Kim , Hyemin Jang , Michael Ewers , Johannes Levin , Reinhold Schmidt , Ofer Pasternak , Martin Dichgans , Geert Jan Biessels , Marco Duering

Genetic determinants of blood lipids and cerebral small vessel disease: role of high-density lipoprotein cholesterol.

Brain : a journal of neurology

Avec: Marios K Georgakis , Rainer Malik , Christopher D Anderson , Klaus G Parhofer , Jemma C Hopewell , Martin Dichgans

Author Correction: Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.

Nature communications

Avec: Gad Abraham , Rainer Malik , Ekaterina Yonova-Doing , Agus Salim , Tingting Wang , John Danesh , Adam S Butterworth , Joanna M M Howson , Michael Inouye , Martin Dichgans

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Nature genetics

Avec: Brian W Kunkle , Benjamin Grenier-Boley , Rebecca Sims , Joshua C Bis , Vincent Damotte , Adam C Naj , Anne Boland , Maria Vronskaya , Sven J van der Lee , Alexandre Amlie-Wolf , Céline Bellenguez , Aura Frizatti , Vincent Chouraki , Eden R Martin , Kristel Sleegers , Nandini Badarinarayan , Johanna Jakobsdottir , Kara L Hamilton-Nelson , Sonia Moreno-Grau , Robert Olaso , Rachel Raybould , Yuning Chen , Amanda B Kuzma , Mikko Hiltunen , Taniesha Morgan , Shahzad Ahmad , Badri N Vardarajan , Jacques Epelbaum , Per Hoffmann , Merce Boada , Gary W Beecham , Jean-Guillaume Garnier , Denise Harold , Annette L Fitzpatrick , Otto Valladares , Marie-Laure Moutet , Amy Gerrish , Albert V Smith , Liming Qu , Delphine Bacq , Nicola Denning , Xueqiu Jian , Yi Zhao , Maria Del Zompo , Nick C Fox , Seung-Hoan Choi , Ignacio Mateo , Joseph T Hughes , Hieab H Adams , John Malamon , Florentino Sanchez-Garcia , Yogen Patel , Jennifer A Brody , Beth A Dombroski , Maria Candida Deniz Naranjo , 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Alvarez , Joseph E Parisi , Andrew B Singleton , Henry L Paulson , John Collinge , William R Perry , Simon Mead , Elaine Peskind , David H Cribbs , Martin Rossor , Aimee Pierce , Natalie S Ryan , Wayne W Poon , Benedetta Nacmias , Huntington Potter , Sandro Sorbi , Joseph F Quinn , Eleonora Sacchinelli , Ashok Raj , Gianfranco Spalletta , Murray Raskind , Carlo Caltagirone , Paola Bossù , Maria Donata Orfei , Barry Reisberg , Robert Clarke , Christiane Reitz , A David Smith , John M Ringman , Donald Warden , Erik D Roberson , Gordon Wilcock , Ekaterina Rogaeva , Amalia Cecilia Bruni , Howard J Rosen , Maura Gallo , Roger N Rosenberg , Yoav Ben-Shlomo , Mark A Sager , Patrizia Mecocci , Andrew J Saykin , Pau Pastor , Michael L Cuccaro , Jeffery M Vance , Julie A Schneider , Lori S Schneider , Susan Slifer , William W Seeley , Amanda G Smith , Joshua A Sonnen , Salvatore Spina , Robert A Stern , Russell H Swerdlow , Mitchell Tang , Rudolph E Tanzi , John Q Trojanowski , Juan C Troncoso , Vivianna M Van Deerlin , Linda J Van Eldik , Harry V Vinters , Jean Paul Vonsattel , Sandra Weintraub , Kathleen A Welsh-Bohmer , Kirk C Wilhelmsen , Jennifer Williamson , Thomas S Wingo , Randall L Woltjer , Clinton B Wright , Chang-En Yu , Lei Yu , Yasaman Saba , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Alberto Pilotto , Maria J Bullido , Oliver Peters , Paul K Crane , David Bennett , Paola Bosco , Eliecer Coto , Virginia Boccardi , Phil L De Jager , Alberto Lleo , Nick Warner , Oscar L Lopez , Martin Ingelsson , Panagiotis Deloukas , Carlos Cruchaga , Caroline Graff , Rhian Gwilliam , Myriam Fornage , Alison M Goate , Pascual Sanchez-Juan , Patrick G Kehoe , Najaf Amin , Nilifur Ertekin-Taner , Claudine Berr , Stéphanie Debette , Seth Love , Lenore J Launer , Steven G Younkin , Jean-Francois Dartigues , Chris Corcoran , M Arfan Ikram , Dennis W Dickson , Gael Nicolas , Dominique Campion , JoAnn Tschanz , Helena Schmidt , Hakon Hakonarson , Jordi Clarimon , Ron Munger , Reinhold Schmidt , Lindsay A Farrer , Christine Van Broeckhoven , Michael C O'Donovan , Anita L DeStefano , Lesley Jones , Jonathan L Haines , Jean-Francois Deleuze , Michael J Owen , Vilmundur Gudnason , Richard Mayeux , Valentina Escott-Price , Bruce M Psaty , Alfredo Ramirez , Li-San Wang , Agustin Ruiz , Cornelia M van Duijn , Peter A Holmans , Sudha Seshadri , Julie Williams , Phillippe Amouyel , Gerard D Schellenberg , Jean-Charles Lambert , Margaret A Pericak-Vance

Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.

PloS one

Avec: Emily Baker , Rebecca Sims , Ganna Leonenko , Aura Frizzati , Janet C Harwood , Detelina Grozeva , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Kevin Morgan , Peter Passmore , Clive Holmes , John Powell , Carol Brayne , Michael Gill , Simon Mead , Paola Bossù , Gianfranco Spalletta , Alison M Goate , Carlos Cruchaga , Wolfgang Maier , Reinhard Heun , Frank Jessen , Oliver Peters , Martin Dichgans , Lutz FröLich , Alfredo Ramirez , Lesley Jones , John Hardy , Dobril Ivanov , Matthew Hill , Peter Holmans , Nicholas D Allen , B Paul Morgan , Sudha Seshadri , Gerard D Schellenberg , Philippe Amouyel , Julie Williams , Valentina Escott-Price

Clinical correlates of longitudinal MRI changes in CADASIL.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Avec: Yifeng Ling , François De Guio , Eric Jouvent , Marco Duering , Dominique Hervé , Jean Pierre Guichard , Ophélia Godin , Martin Dichgans , Hugues Chabriat

Cardiovascular Risk and Atherosclerosis Progression in Hypertensive Persons Treated to Blood Pressure Targets.

Hypertension (Dallas, Tex. : 1979)

Avec: Janine Gronewold , Rene Kropp , Nils Lehmann , Andreas Stang , Amir A Mahabadi , Hagen Kälsch , Christian Weimar , Martin Dichgans , Thomas Budde , Susanne Moebus , Karl-Heinz Jöckel , Raimund Erbel , Dirk M Hermann

Genetic variation in

Neurology

Avec: Matthew Traylor , Daniel J Tozer , Iain D Croall , Danuta M Lisiecka-Ford , Abiodun Olubunmi Olorunda , Giorgio Boncoraglio , Martin Dichgans , Robin Lemmens , Jonathan Rosand , Natalia S Rost , Peter M Rothwell , Cathie L M Sudlow , Vincent Thijs , Loes Rutten-Jacobs , Hugh S Markus , Auteur inconnu

The Atherosclerosis Risk Variant rs2107595 Mediates Allele-Specific Transcriptional Regulation of

Stroke

Avec: Matthias Prestel , Caroline Prell-Schicker , Tom Webb , Rainer Malik , Barbara Lindner , Natalie Ziesch , Monika Rex-Haffner , Simone Röh , Thanatip Viturawong , Manuel Lehm , Michal Mokry , Hester den Ruijter , Saskia Haitjema , Yaw Asare , Flavia Söllner , Maryam Ghaderi Najafabadi , Rédouane Aherrahrou , Mete Civelek , Nilesh J Samani , Matthias Mann , Christof Haffner , Martin Dichgans

Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade.

Immunity

Avec: Stefan Roth , Jiayu Cao , Vikramjeet Singh , Steffen Tiedt , Gabriel Hundeshagen , Ting Li , Julia D Boehme , Dhruv Chauhan , Jie Zhu , Alessio Ricci , Oliver Gorka , Yaw Asare , Jun Yang , Mary S Lopez , Markus Rehberg , Dunja Bruder , Shengxiang Zhang , Olaf Groß , Martin Dichgans , Veit Hornung , Arthur Liesz

Mendelian randomization for studying the effects of perturbing drug targets.

Wellcome open research

Avec: Dipender Gill , Marios K Georgakis , Venexia M Walker , A Floriaan Schmidt , Apostolos Gkatzionis , Daniel F Freitag , Chris Finan , Aroon D Hingorani , Joanna M M Howson , Stephen Burgess , Daniel I Swerdlow , George Davey Smith , Michael V Holmes , Martin Dichgans , Robert A Scott , Jie Zheng , Bruce M Psaty , Neil M Davies

Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease: A Mendelian Randomization Study.

Neurology

Avec: Marios K Georgakis , Eric L Harshfield , Rainer Malik , Nora Franceschini , Claudia Langenberg , Nicholas J Wareham , Hugh S Markus , Martin Dichgans

Modifiable Lifestyle Factors and Risk of Stroke: A Mendelian Randomization Analysis.

Stroke

Avec: Eric L Harshfield , Marios K Georgakis , Rainer Malik , Martin Dichgans , Hugh S Markus

Genetic overlap and causal inferences between kidney function and cerebrovascular disease.

Neurology

Avec: Sandro Marini , Marios K Georgakis , Jaeyoon Chung , Jonathan Q A Henry , Martin Dichgans , Jonathan Rosand , Rainer Malik , Christopher D Anderson

Complicated Carotid Artery Plaques as a Cause of Cryptogenic Stroke.

Journal of the American College of Cardiology

Avec: Anna Kopczak , Andreas Schindler , Anna Bayer-Karpinska , Mia L Koch , Dominik Sepp , Julia Zeller , Christoph Strecker , Johann-Martin Hempel , Chun Yuan , Rainer Malik , Frank A Wollenweber , Tobias Boeckh-Behrens , Clemens C Cyran , Andreas Helck , Andreas Harloff , Ulf Ziemann , Sven Poli , Holger Poppert , Martin Dichgans , Tobias Saam

Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensities.

Brain : a journal of neurology

Avec: Rainer Malik , Nathalie Beaufort , Simon Frerich , Benno Gesierich , Marios K Georgakis , Kristiina Rannikmäe , Amy C Ferguson , Christof Haffner , Matthew Traylor , Michael Ehrmann , Cathie L M Sudlow , Martin Dichgans

Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model.

The Journal of clinical investigation

Avec: Eva Auffenberg , Ulrike Bs Hedrich , Raffaella Barbieri , Daniela Miely , Bernhard Groschup , Thomas V Wuttke , Niklas Vogel , Philipp Lührs , Ilaria Zanardi , Sara Bertelli , Nadine Spielmann , Valerie Gailus-Durner , Helmut Fuchs , Martin Hrabě de Angelis , Michael Pusch , Martin Dichgans , Holger Lerche , Paola Gavazzo , Nikolaus Plesnila , Tobias Freilinger

Tau-PET and in vivo Braak-staging as prognostic markers of future cognitive decline in cognitively normal to demented individuals.

Alzheimer's research & therapy

Avec: Davina Biel , Matthias Brendel , Anna Rubinski , Katharina Buerger , Daniel Janowitz , Martin Dichgans , Nicolai Franzmeier , Auteur inconnu

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores.

Nature communications

Avec: Itziar de Rojas , Sonia Moreno-Grau , Niccolo Tesi , Benjamin Grenier-Boley , Victor Andrade , Iris E Jansen , Nancy L Pedersen , Najada Stringa , Anna Zettergren , Isabel Hernández , Laura Montrreal , Carmen Antúnez , Anna Antonell , Rick M Tankard , Joshua C Bis , Rebecca Sims , Céline Bellenguez , Inés Quintela , Antonio González-Perez , Miguel Calero , Emilio Franco-Macías , Juan Macías , Rafael Blesa , Laura Cervera-Carles , Manuel Menéndez-González , Ana Frank-García , Jose Luís Royo , Fermin Moreno , Raquel Huerto Vilas , Miquel Baquero , Mónica Diez-Fairen , Carmen Lage , Sebastián García-Madrona , Pablo García-González , Emilio Alarcón-Martín , Sergi Valero , Oscar Sotolongo-Grau , Abbe Ullgren , Adam C Naj , Afina W Lemstra , Alba Benaque , Alba Pérez-Cordón , Alberto Benussi , Alberto Rábano , Alessandro Padovani , Alessio Squassina , Alexandre de Mendonça , Alfonso Arias Pastor , Almar A L Kok , Alun Meggy , Ana Belén Pastor , Ana Espinosa , Anaïs Corma-Gómez , Angel Martín Montes , Ángela Sanabria , Anita L DeStefano , Anja Schneider , Annakaisa Haapasalo , Anne Kinhult Ståhlbom , Anne Tybjærg-Hansen , Annette M Hartmann , Annika Spottke , Arturo Corbatón-Anchuelo , Arvid Rongve , Barbara Borroni , Beatrice Arosio , Benedetta Nacmias , Børge G Nordestgaard , Brian W Kunkle , Camille Charbonnier , Carla Abdelnour , Carlo Masullo , Carmen Martínez Rodríguez , Carmen Muñoz-Fernandez , Carole Dufouil , Caroline Graff , Catarina B Ferreira , Caterina Chillotti , Chandra A Reynolds , Chiara Fenoglio , Christine Van Broeckhoven , Christopher Clark , Claudia Pisanu , Claudia L Satizabal , Clive Holmes , Dolores Buiza-Rueda , Dag Aarsland , Dan Rujescu , Daniel Alcolea , Daniela Galimberti , David Wallon , Davide Seripa , Edna Grünblatt , Efthimios Dardiotis , Emrah Düzel , Elio Scarpini , Elisa Conti , Elisa Rubino , Ellen Gelpi , Eloy Rodriguez-Rodriguez , Emmanuelle Duron , Eric Boerwinkle , Evelyn Ferri , Fabrizio Tagliavini , Fahri Küçükali , Florence Pasquier , Florentino Sanchez-Garcia , Francesca Mangialasche , Frank Jessen , Gaël Nicolas , Geir Selbæk , Gemma Ortega , Geneviève Chêne , Georgios Hadjigeorgiou , Giacomina Rossi , Gianfranco Spalletta , Giorgio Giaccone , Giulia Grande , Giuliano Binetti , Goran Papenberg , Harald Hampel , Henri Bailly , Henrik Zetterberg , Hilkka Soininen , Ida K Karlsson , Ignacio Alvarez , Ildebrando Appollonio , Ina Giegling , Ingmar Skoog , Ingvild Saltvedt , Innocenzo Rainero , Irene Rosas Allende , Jakub Hort , Janine Diehl-Schmid , Jasper Van Dongen , Jean-Sebastien Vidal , Jenni Lehtisalo , Jens Wiltfang , Jesper Qvist Thomassen , Johannes Kornhuber , Jonathan L Haines , Jonathan Vogelgsang , Juan A Pineda , Juan Fortea , Julius Popp , Jürgen Deckert , Katharina Buerger , Kevin Morgan , Klaus Fließbach , Kristel Sleegers , Laura Molina-Porcel , Lena Kilander , Leonie Weinhold , Lindsay A Farrer , Li-San Wang , Luca Kleineidam , Lucia Farotti , Lucilla Parnetti , Lucio Tremolizzo , Lucrezia Hausner , Luisa Benussi , Lutz Froelich , M Arfan Ikram , M Candida Deniz-Naranjo , Magda Tsolaki , Maitée Rosende-Roca , Malin Löwenmark , Marc Hulsman , Marco Spallazzi , Margaret A Pericak-Vance , Margaret Esiri , María Bernal Sánchez-Arjona , Maria Carolina Dalmasso , María Teresa Martínez-Larrad , Marina Arcaro , Markus M Nöthen , Marta Fernández-Fuertes , Martin Dichgans , Martin Ingelsson , Martin J Herrmann , Martin Scherer , Martin Vyhnalek , Mary H Kosmidis , Mary Yannakoulia , Matthias Schmid , Michael Ewers , Michael T Heneka , Michael Wagner , Michela Scamosci , Miia Kivipelto , Mikko Hiltunen , Miren Zulaica , Montserrat Alegret , Myriam Fornage , Natalia Roberto , Natasja M van Schoor , Nazib M Seidu , Nerisa Banaj , Nicola J Armstrong , Nikolaos Scarmeas , Norbert Scherbaum , Oliver Goldhardt , Oliver Hanon , Oliver Peters , Olivia Anna Skrobot , Olivier Quenez , Ondrej Lerch , Paola Bossù , Paolo Caffarra , Paolo Dionigi Rossi , Paraskevi Sakka , Patrizia Mecocci , Per Hoffmann , Peter A Holmans , Peter Fischer , Peter Riederer , Qiong Yang , Rachel Marshall , Rajesh N Kalaria , Richard Mayeux , Rik Vandenberghe , Roberta Cecchetti , Roberta Ghidoni , Ruth Frikke-Schmidt , Sandro Sorbi , Sara Hägg , Sebastiaan Engelborghs , Seppo Helisalmi , Sigrid Botne Sando , Silke Kern , Silvana Archetti , Silvia Boschi , Silvia Fostinelli , Silvia Gil , Silvia Mendoza , Simon Mead , Simona Ciccone , Srdjan Djurovic , Stefanie Heilmann-Heimbach , Steffi Riedel-Heller , Teemu Kuulasmaa , Teodoro Del Ser , Thibaud Lebouvier , Thomas Polak , Tiia Ngandu , Timo Grimmer , Valentina Bessi , Valentina Escott-Price , Vilmantas Giedraitis , Vincent Deramecourt , Wolfgang Maier , Xueqiu Jian , Yolande A L Pijnenburg , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Auteur inconnu , Patrick Gavin Kehoe , Guillermo Garcia-Ribas , Pascual Sánchez-Juan , Pau Pastor , Jordi Pérez-Tur , Gerard Piñol-Ripoll , Adolfo Lopez de Munain , Jose María García-Alberca , María J Bullido , Victoria Álvarez , Alberto Lleó , Luis M Real , Pablo Mir , Miguel Medina , Philip Scheltens , Henne Holstege , Marta Marquié , María Eugenia Sáez , Ángel Carracedo , Philippe Amouyel , Gerard D Schellenberg , Julie Williams , Sudha Seshadri , Cornelia M van Duijn , Karen A Mather , Raquel Sánchez-Valle , Manuel Serrano-Ríos , Adelina Orellana , Lluís Tárraga , Kaj Blennow , Martijn Huisman , Ole A Andreassen , Danielle Posthuma , Jordi Clarimón , Mercè Boada , Wiesje M van der Flier , Alfredo Ramirez , Jean-Charles Lambert , Sven J van der Lee , Agustín Ruiz

Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease.

Circulation

Avec: Michael G Levin , Verena Zuber , Venexia M Walker , Derek Klarin , Julie Lynch , Rainer Malik , Aaron W Aday , Leonardo Bottolo , Aruna D Pradhan , Martin Dichgans , Kyong-Mi Chang , Daniel J Rader , Philip S Tsao , Benjamin F Voight , Dipender Gill , Stephen Burgess , Scott M Damrauer

The BS variant of C4 protects against age-related loss of white matter microstructural integrity.

Brain : a journal of neurology

Avec: Matthew Traylor , Rainer Malik , Benno Gesierich , Martin Dichgans

Cardiac Risk Factors for Stroke: A Comprehensive Mendelian Randomization Study.

Stroke

Avec: Simon Frerich , Rainer Malik , Marios K Georgakis , Moritz F Sinner , Steven J Kittner , Braxton D Mitchell , Martin Dichgans

Physician-Confirmed and Administrative Definitions of Stroke in UK Biobank Reflect the Same Underlying Genetic Trait.

Frontiers in neurology

Avec: Kristiina Rannikmäe , Konrad Rawlik , Amy C Ferguson , Nikos Avramidis , Muchen Jiang , Nicola Pirastu , Xia Shen , Emma Davidson , Rebecca Woodfield , Rainer Malik , Martin Dichgans , Albert Tenesa , Cathie Sudlow

Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease.

JAMA neurology

Avec: Yann Le Guen , Michael E Belloy , Benjamin Grenier-Boley , Itziar de Rojas , Atahualpa Castillo-Morales , Iris Jansen , Aude Nicolas , Céline Bellenguez , Carolina Dalmasso , Fahri Küçükali , Sarah J Eger , Katrine Laura Rasmussen , Jesper Qvist Thomassen , Jean-François Deleuze , Zihuai He , Valerio Napolioni , Philippe Amouyel , Frank Jessen , Patrick G Kehoe , Cornelia van Duijn , Magda Tsolaki , Pascual Sánchez-Juan , Kristel Sleegers , Martin Ingelsson , Giacomina Rossi , Mikko Hiltunen , Rebecca Sims , Wiesje M van der Flier , Alfredo Ramirez , Ole A Andreassen , Ruth Frikke-Schmidt , Julie Williams , Agustín Ruiz , Jean-Charles Lambert , Michael D Greicius , Auteur inconnu , Beatrice Arosio , Luisa Benussi , Anne Boland , Barbara Borroni , Paolo Caffarra , Delphine Daian , Antonio Daniele , Stéphanie Debette , Carole Dufouil , Emrah Düzel , Daniela Galimberti , Vilmantas Giedraitis , Timo Grimmer , Caroline Graff , Edna Grünblatt , Olivier Hanon , Lucrezia Hausner , Stefanie Heilmann-Heimbach , Henne Holstege , Jakub Hort , Deckert Jürgen , Teemu Kuulasmaa , Aad van der Lugt , Carlo Masullo , Patrizia Mecocci , Shima Mehrabian , Alexandre de Mendonça , Susanne Moebus , Benedetta Nacmias , Gael Nicolas , Robert Olaso , Goran Papenberg , Lucilla Parnetti , Florence Pasquier , Oliver Peters , Yolande A L Pijnenburg , Julius Popp , Innocenzo Rainero , Inez Ramakers , Steffi Riedel-Heller , Nikolaos Scarmeas , Philip Scheltens , Norbert Scherbaum , Anja Schneider , Davide Seripa , Hilkka Soininen , Vincenzo Solfrizzi , Gianfranco Spalletta , Alessio Squassina , John van Swieten , Thomas J Tegos , Lucio Tremolizzo , Frans Verhey , Martin Vyhnalek , Jens Wiltfang , Mercè Boada , Pablo García-González , Raquel Puerta , Luis M Real , Victoria Álvarez , María J Bullido , Jordi Clarimon , José María García-Alberca , Pablo Mir , Fermin Moreno , Pau Pastor , Gerard Piñol-Ripoll , Laura Molina-Porcel , Jordi Pérez-Tur , Eloy Rodríguez-Rodríguez , Jose Luís Royo , Raquel Sánchez-Valle , Martin Dichgans , Dan Rujescu

Targeting the CCL2-CCR2 axis for atheroprotection.

European heart journal

Avec: Marios K Georgakis , Jürgen Bernhagen , Laura H Heitman , Christian Weber , Martin Dichgans

Determining the OPTIMAL DTI analysis method for application in cerebral small vessel disease.

NeuroImage. Clinical

Avec: Marco Egle , Saima Hilal , Anil M Tuladhar , Lukas Pirpamer , Steven Bell , Edith Hofer , Marco Duering , James Wason , Robin G Morris , Martin Dichgans , Reinhold Schmidt , Daniel J Tozer , Thomas R Barrick , Christopher Chen , Frank-Erik de Leeuw , Hugh S Markus

The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial.

European stroke journal

Avec: Anna Kopczak , Michael S Stringer , Hilde van den Brink , Danielle Kerkhofs , Gordon W Blair , Maud van Dinther , Laurien Onkenhout , Karolina A Wartolowska , Michael J Thrippleton , Marco Duering , Julie Staals , Martin Middeke , Elisabeth André , Bo Norrving , Marie-Germaine Bousser , Ulrich Mansmann , Peter M Rothwell , Fergus N Doubal , Robert van Oostenbrugge , Geert Jan Biessels , Alastair Js Webb , Joanna M Wardlaw , Martin Dichgans

Polygenic Effect on Tau Pathology Progression in Alzheimer's Disease.

Annals of neurology

Avec: Anna Rubinski , Simon Frerich , Rainer Malik , Nicolai Franzmeier , Alfredo Ramirez , Martin Dichgans , Michael Ewers , Auteur inconnu

The interplay between inflammatory cytokines and cardiometabolic disease: bi-directional mendelian randomisation study.

BMJ medicine

Avec: Ville Karhunen , Dipender Gill , Jian Huang , Emmanouil Bouras , Rainer Malik , Mark J Ponsford , Ari Ahola-Olli , Areti Papadopoulou , Saranya Palaniswamy , Sylvain Sebert , Matthias Wielscher , Juha Auvinen , Juha Veijola , Karl-Heinz Herzig , Markku Timonen , Sirkka Keinänen-Kiukaanniemi , Martin Dichgans , Marko Salmi , Sirpa Jalkanen , Terho Lehtimäki , Veikko Salomaa , Olli Raitakari , Simon A Jones , G Kees Hovingh , Konstantinos K Tsilidis , Marjo-Riitta Järvelin , Abbas Dehghan

Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial.

The Lancet. Neurology

Avec: Anna Kopczak , Michael S Stringer , Hilde van den Brink , Danielle Kerkhofs , Gordon W Blair , Maud van Dinther , Carmen Arteaga Reyes , Daniela Jaime Garcia , Laurien Onkenhout , Karolina A Wartolowska , Michael J Thrippleton , Agniete Kampaite , Marco Duering , Julie Staals , Saskia Lesnik-Oberstein , Keith W Muir , Martin Middeke , Bo Norrving , Marie-Germaine Bousser , Ulrich Mansmann , Peter M Rothwell , Fergus N Doubal , Robert van Oostenbrugge , Geert Jan Biessels , Alastair J S Webb , Joanna M Wardlaw , Martin Dichgans , Auteur inconnu

Réseau de co-auteurs

Martin Dichgans 97 collaborations

None None 74 collaborations

Rainer Malik 37 collaborations

Marios K Georgakis 28 collaborations

Marco Duering 20 collaborations

Michael Ewers 14 collaborations

Hugh S Markus 14 collaborations

Nicolai Franzmeier 13 collaborations

Jonathan Rosand 11 collaborations

Christopher D Anderson 11 collaborations

Dipender Gill 10 collaborations

Joanna M Wardlaw 10 collaborations

Geert Jan Biessels 8 collaborations

Philippe Amouyel 8 collaborations

Bradford B Worrall 8 collaborations

Anna Kopczak 8 collaborations

Benno Gesierich 7 collaborations

Carlos Cruchaga 7 collaborations

Matthew Traylor 7 collaborations

Reinhold Schmidt 7 collaborations

Daniel Woo 7 collaborations

Braxton D Mitchell 7 collaborations

Stéphanie Debette 7 collaborations

Steffen Tiedt 7 collaborations

Arthur Liesz 6 collaborations

Joshua C Bis 6 collaborations

Bruce M Psaty 6 collaborations

Tatjana Rundek 6 collaborations

Peter M Rothwell 6 collaborations

Steven J Kittner 6 collaborations

Myriam Fornage 6 collaborations

Sudha Seshadri 6 collaborations

Katharina Buerger 6 collaborations

Matthias Brendel 6 collaborations

Frank-Erik de Leeuw 6 collaborations

Stephen Burgess 6 collaborations

Matthias Endres 6 collaborations

Yaw Asare 6 collaborations

Frank Jessen 6 collaborations

Oliver Peters 6 collaborations

Alfredo Ramirez 6 collaborations

Cathie L M Sudlow 5 collaborations

Stefan Roth 5 collaborations

Christian Haass 5 collaborations

Muralidharan Sargurupremraj 5 collaborations

Thomas H Mosley 5 collaborations

Robin Lemmens 5 collaborations

James F Meschia 5 collaborations

Vincent Thijs 5 collaborations

Christina Jern 5 collaborations

Anna Dewenter 5 collaborations

Anna Rubinski 5 collaborations

Gabor C Petzold 5 collaborations

Johannes Levin 4 collaborations

Hugues Chabriat 4 collaborations

John Q Trojanowski 4 collaborations

Frank A Wollenweber 4 collaborations

Xueqiu Jian 4 collaborations

Gerard D Schellenberg 4 collaborations

Jerome I Rotter 4 collaborations

Christopher Chen 4 collaborations

Jordi Jimenez-Conde 4 collaborations

John W Cole 4 collaborations

Agnieszka Slowik 4 collaborations

Raji P Grewal 4 collaborations

Jin-Moo Lee 4 collaborations

Stephen S Rich 4 collaborations

W T Longstreth 4 collaborations

Israel Fernandez-Cadenas 4 collaborations

Veikko Salomaa 4 collaborations

Sandro Marini 4 collaborations

Ramin Zand 4 collaborations

Huichun Xu 4 collaborations

Yoichiro Kamatani 4 collaborations

Masaru Koido 4 collaborations

Turgut Tatlisumak 4 collaborations

Anil M Tuladhar 4 collaborations

Joanna M M Howson 4 collaborations

Davina Biel 4 collaborations

Laurien Onkenhout 4 collaborations

Michael S Stringer 4 collaborations

Bo Norrving 4 collaborations

Nathalie Beaufort 4 collaborations

Regina von Rennenberg 4 collaborations

Susanne Moebus 4 collaborations

Daniel Janowitz 4 collaborations

Anja Schneider 4 collaborations

Jens Wiltfang 4 collaborations

Emrah Düzel 4 collaborations

Simon Frerich 4 collaborations

Rebecca Sims 4 collaborations

Gianfranco Spalletta 4 collaborations

Julie Williams 4 collaborations

Alastair J S Webb 3 collaborations

Abbas Dehghan 3 collaborations

Julie W Rutten 3 collaborations

Eric Jouvent 3 collaborations

Leonardo Pantoni 3 collaborations

Saskia A J Lesnik Oberstein 3 collaborations

Estrella Morenas-Rodriguez 3 collaborations

Gernot Kleinberger 3 collaborations

Hugo J Kuijf 3 collaborations

Saima Hilal 3 collaborations

Claudia L Satizabal 3 collaborations

Edith Hofer 3 collaborations

Rebecca F Gottesman 3 collaborations

Sven J van der Lee 3 collaborations

Anita L DeStefano 3 collaborations

Jemma C Hopewell 3 collaborations

Ralph L Sacco 3 collaborations

Pankaj Sharma 3 collaborations

Arne Lindgren 3 collaborations

Oscar R Benavente 3 collaborations

Cornelia M van Duijn 3 collaborations

Lenore J Launer 3 collaborations

Liisa Tomppo 3 collaborations

Vida Abedi 3 collaborations

Mark K Bakker 3 collaborations

Steven Bell 3 collaborations

Daniel J Tozer 3 collaborations

Daniel Strbian 3 collaborations

Lukas Frontzkowski 3 collaborations

Zhengming Chen 3 collaborations

Christian Gieger 3 collaborations

Mina A Jacob 3 collaborations

Jiang Li 3 collaborations

Liming Li 3 collaborations

Kuang Lin 3 collaborations

Joanna Pera 3 collaborations

Annette Peters 3 collaborations

Chikashi Terao 3 collaborations

Robin G Walters 3 collaborations

Hilde van den Brink 3 collaborations

Gordon W Blair 3 collaborations

Fergus N Doubal 3 collaborations

Michael J Thrippleton 3 collaborations

Scott M Damrauer 3 collaborations

Mikael Simons 3 collaborations

Silke Wunderlich 3 collaborations

Jiayu Cao 3 collaborations

Olga Carofiglio 3 collaborations

Nikolaus Plesnila 3 collaborations

Ozgun Gokce 3 collaborations

Carl D Langefeld 3 collaborations

Henne Holstege 3 collaborations

Christof Haffner 3 collaborations

Jürgen Bernhagen 3 collaborations

Christian H Nolte 3 collaborations

Philip Scheltens 3 collaborations

Jaeyoon Chung 3 collaborations

Eric Boerwinkle 3 collaborations

Karl-Heinz Jöckel 3 collaborations

Kristiina Rannikmäe 3 collaborations

Livia Parodi 3 collaborations

Ernst Mayerhofer 3 collaborations

Annika Spottke 3 collaborations

Michael T Heneka 3 collaborations

Danielle Kerkhofs 3 collaborations

Julie Staals 3 collaborations

Robert van Oostenbrugge 3 collaborations

Jesper Qvist Thomassen 3 collaborations

Qiong Yang 3 collaborations

Ruth Frikke-Schmidt 3 collaborations

Benjamin Grenier-Boley 3 collaborations

Céline Bellenguez 3 collaborations

Kristel Sleegers 3 collaborations

Mikko Hiltunen 3 collaborations

Daniela Galimberti 3 collaborations

Alessio Squassina 3 collaborations

Clive Holmes 3 collaborations

Wolfgang Maier 3 collaborations

Vilmantas Giedraitis 3 collaborations

Carole Dufouil 3 collaborations

Itziar de Rojas 3 collaborations

Magda Tsolaki 3 collaborations

Hilkka Soininen 3 collaborations

Paolo Caffarra 3 collaborations

Florence Pasquier 3 collaborations

Carlo Masullo 3 collaborations

Luis M Real 3 collaborations

Kevin Morgan 3 collaborations

Steffi Riedel-Heller 3 collaborations

Simon Mead 3 collaborations

Benedetta Nacmias 3 collaborations

Paola Bossù 3 collaborations

Patrizia Mecocci 3 collaborations

Pau Pastor 3 collaborations

Martin Ingelsson 3 collaborations

Caroline Graff 3 collaborations

Valentina Escott-Price 3 collaborations

Jean-Charles Lambert 3 collaborations

Evangelos Evangelou 2 collaborations

Paul Elliott 2 collaborations

Ioanna Tzoulaki 2 collaborations

Celeste M Karch 2 collaborations

Martin Rossor 2 collaborations

Nick C Fox 2 collaborations

Stephen Salloway 2 collaborations

Peter R Schofield 2 collaborations

John C Morris 2 collaborations

Bastian J Van Eijsden 2 collaborations

Christian Opherk 2 collaborations

Antonio Federico 2 collaborations

Marc Suárez-Calvet 2 collaborations

Laura Piccio 2 collaborations

Yuetiva Deming 2 collaborations

Nick A Weaver 2 collaborations

Hee-Joon Bae 2 collaborations

Vincent C T Mok 2 collaborations

Adrian Wong 2 collaborations

Ganesh Chauhan 2 collaborations

Stella Trompet 2 collaborations

Sabrina Schilling 2 collaborations

Gary W Beecham 2 collaborations

Thomas J Montine 2 collaborations

Yasaman Saba 2 collaborations

Helena Schmidt 2 collaborations

Denis A Evans 2 collaborations

Oscar L Lopez 2 collaborations

Najaf Amin 2 collaborations

Vincent Chouraki 2 collaborations

Charles DeCarli 2 collaborations

Giorgio B Boncoraglio 2 collaborations

Clinton B Wright 2 collaborations

Nicola J Armstrong 2 collaborations

J Wouter Jukema 2 collaborations

Aad van der Lugt 2 collaborations

Hans J Grabe 2 collaborations

Olle Melander 2 collaborations

Donna K Arnett 2 collaborations

Julie A Johnson 2 collaborations

Patrick F McArdle 2 collaborations

Mirjam I Geerlings 2 collaborations

Velandai Srikanth 2 collaborations

Karen A Mather 2 collaborations

Mohammad A Ikram 2 collaborations

S Sacco 2 collaborations

Arne G Lindgren 2 collaborations

Jane Maguire 2 collaborations

Laura Heitsch 2 collaborations

Kameshwar Prasad 2 collaborations

Natalia S Rost 2 collaborations

Linxin Li 2 collaborations

Loes Rutten-Jacobs 2 collaborations

Joanna Wardlaw 2 collaborations

Cathryn M Lewis 2 collaborations

Julia Neitzel 2 collaborations

Ruben Smith 2 collaborations

Olof Strandberg 2 collaborations

Rik Ossenkoppele 2 collaborations

Oskar Hansson 2 collaborations

Nicole D Armstrong 2 collaborations

Michael Chong 2 collaborations

John Danesh 2 collaborations

Stephanie Debette 2 collaborations

Aki S Havulinna 2 collaborations

Marguerite R Irvin 2 collaborations

Martin O'Donnell 2 collaborations

Nicholas L Smith 2 collaborations

Sylvia Wassertheil-Smoller 2 collaborations

Nuria P Torres-Aguila 2 collaborations

Jan H Veldink 2 collaborations

Guillaume Pare 2 collaborations

G Kees Hovingh 2 collaborations

Paul Hager 2 collaborations

Tine Arts 2 collaborations

Jeroen Hendrikse 2 collaborations

Francesca Romana Pezzella 2 collaborations

Cristina Tiu 2 collaborations

Alastair Webb 2 collaborations

Jens Fiehler 2 collaborations

Charles Kooperberg 2 collaborations

Anna Steward 2 collaborations

Quentin Le Grand 2 collaborations

Katalin Todorov-Völgyi 2 collaborations

Stephan A Müller 2 collaborations

Martina Schifferer 2 collaborations

Dennis Crusius 2 collaborations

Andree Schmidt 2 collaborations

Dominik Paquet 2 collaborations

Stefan F Lichtenthaler 2 collaborations

Friederike A Arlt 2 collaborations

Bianca Teegen 2 collaborations

Rong Fang 2 collaborations

Michael Görtler 2 collaborations

Inga Zerr 2 collaborations

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Alba Simats 2 collaborations

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Denise Messerer 2 collaborations

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Alessio Ricci 2 collaborations

Christian Braun 2 collaborations

Christian Schulz 2 collaborations

Jie Zhu 2 collaborations

Veit Hornung 2 collaborations

Bailey E Montgomery 2 collaborations

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Mike A Nalls 2 collaborations

Matthias Prestel 2 collaborations

Omar El Bounkari 2 collaborations

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Guangyao Yan 2 collaborations

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Oliver Soehnlein 2 collaborations

Simon Litmeier 2 collaborations

Jan F Scheitz 2 collaborations

David M Leistner 2 collaborations

Stephan Blankenberg 2 collaborations

Hugo Katus 2 collaborations

Burkert Pieske 2 collaborations

Vera Regitz-Zagrosek 2 collaborations

Karl Wegscheider 2 collaborations

Andreas M Zeiher 2 collaborations

Ulf Landmesser 2 collaborations

Sarah Pendlebury 2 collaborations

Charlotte Cordonnier 2 collaborations

Steven M Greenberg 2 collaborations

Miia Kivipelto 2 collaborations

John O'Brien 2 collaborations

Perminder Sachdev 2 collaborations

Ingmar Skoog 2 collaborations

Eric E Smith 2 collaborations

Tobias Boeckh-Behrens 2 collaborations

Catharina J M Klijn 2 collaborations

Anna Bayer-Karpinska 2 collaborations

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Leslie Shaw 2 collaborations

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Andreas Stang 2 collaborations

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Robert Perneczky 2 collaborations

Josef Priller 2 collaborations

Michael Wagner 2 collaborations

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Michael Inouye 2 collaborations

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Neill R Graff-Radford 2 collaborations

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Anne Boland 2 collaborations

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Per Hoffmann 2 collaborations

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David Wallon 2 collaborations

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Eloy Rodriguez-Rodriguez 2 collaborations

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Lesley Jones 2 collaborations

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Richard Mayeux 2 collaborations

Li-San Wang 2 collaborations

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Venexia M Walker 2 collaborations

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Amy C Ferguson 2 collaborations

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Fermin Moreno 2 collaborations

Pablo García-González 2 collaborations

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Dan Rujescu 2 collaborations

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Timo Grimmer 2 collaborations

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Gerard Piñol-Ripoll 2 collaborations

María J Bullido 2 collaborations

Victoria Álvarez 2 collaborations

Pablo Mir 2 collaborations

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Maud van Dinther 2 collaborations

Karolina A Wartolowska 2 collaborations

Martin Middeke 2 collaborations

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Nikolaos Koutsouleris 1 collaboration

Tammie Benzinger 1 collaboration

Alison Goate 1 collaboration

Anne M Fagan 1 collaboration

Eric McDade 1 collaboration

Brian A Gordon 1 collaboration

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Jason Hassenstab 1 collaboration

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Michael W Weiner 1 collaboration

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Lan Jiang 1 collaboration

Qiping Feng 1 collaboration

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Francesca M Chappell 1 collaboration

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Lin Shi 1 collaboration

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Xu Xin 1 collaboration

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Alexander Teumer 1 collaboration

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Kenneth Rice 1 collaboration

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Ching-Yu Cheng 1 collaboration

Tien Y Wong 1 collaboration

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Chris Moran 1 collaboration

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Thanh Phan 1 collaboration

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Perminder S Sachdev 1 collaboration

T Steiner 1 collaboration

B Norrving 1 collaboration

A H Aamodt 1 collaboration

E Berge 1 collaboration

H Christensen 1 collaboration

B Fuentes 1 collaboration

P Khatri 1 collaboration

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T Quinn 1 collaboration

D Toni 1 collaboration

M Zedde 1 collaboration

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